phalloguy100
Active Member
Hi everyone. I am looking for your collective wisdom here on E2, low libido, and possibly switching to Jatenzo. My urologist appointment is coming up in a few days so I want to figure out what to ask the doctor!
I have secondary hypogonadism. I am currently on Testosterone Enanthate (allergic to something in cypionate), doing 0.3mL/60mg subq 3x per week. I am also on hcg 500 iu 4x per week, and anastrazole up to 1mg every 3 days (though I usually only do half or 0.5mg). Although libido is hit or miss from week to week, and maintaining erections is still difficult (I take cialis daily and sometimes trimix shots), overall, I think it's working well.
Lab numbers are mostly good, except estrogen that sometimes goes 15-20 (kind of low) while free E stays high. TT 750s, hematocrit 48-49. SHBG is low normal. Prolactin, TSH and T4 all normal. Free T si slightly high. I have monogenic diabetes (with high insulin sensitivity), and I now use an insulin pump which is keeping me at an amazing a1c of 5.3 while preventing low blood sugars.
To start with, the anastrazole dose seems too high, right? Even at 0.5mg? The urologist started me on it when my E2 shot up to 80, so maybe that's why he prescribed something so high but I told him from the start I would probably take only half of that and he said it was fine. SHBG is low normal. I'm pretty sure the low E2 is what's affecting libido since the diabetes is well controlled.
Besides lowering E2, the other thing that's getting to me is the shots. It's just way too many. At least I am no longer doing insulin shots several times a day, but all these T shots are getting old. So, I am thinking, should I try less frequent shots at a higher dose each? Or should I try switching to Jatenzo? I don't think I mind taking pills twice a day, plus I read that even though T has huge daily peaks and valleys, libido actually improves and DHT goes up with oral TU. The majority of posts here about switching to Jatenzo sound like they were a good move with only one user switching back to shots.
I have tried Androgel and Natesto in the past and they were awful. Absorption was very inconsistent, while the gel irritates my skin every time. Natesto just didn't work - peak TT was 450s - and it would often end up in the back of my throat tasting bitter.
I'd appreciate your thoughts!
I have secondary hypogonadism. I am currently on Testosterone Enanthate (allergic to something in cypionate), doing 0.3mL/60mg subq 3x per week. I am also on hcg 500 iu 4x per week, and anastrazole up to 1mg every 3 days (though I usually only do half or 0.5mg). Although libido is hit or miss from week to week, and maintaining erections is still difficult (I take cialis daily and sometimes trimix shots), overall, I think it's working well.
Lab numbers are mostly good, except estrogen that sometimes goes 15-20 (kind of low) while free E stays high. TT 750s, hematocrit 48-49. SHBG is low normal. Prolactin, TSH and T4 all normal. Free T si slightly high. I have monogenic diabetes (with high insulin sensitivity), and I now use an insulin pump which is keeping me at an amazing a1c of 5.3 while preventing low blood sugars.
To start with, the anastrazole dose seems too high, right? Even at 0.5mg? The urologist started me on it when my E2 shot up to 80, so maybe that's why he prescribed something so high but I told him from the start I would probably take only half of that and he said it was fine. SHBG is low normal. I'm pretty sure the low E2 is what's affecting libido since the diabetes is well controlled.
Besides lowering E2, the other thing that's getting to me is the shots. It's just way too many. At least I am no longer doing insulin shots several times a day, but all these T shots are getting old. So, I am thinking, should I try less frequent shots at a higher dose each? Or should I try switching to Jatenzo? I don't think I mind taking pills twice a day, plus I read that even though T has huge daily peaks and valleys, libido actually improves and DHT goes up with oral TU. The majority of posts here about switching to Jatenzo sound like they were a good move with only one user switching back to shots.
I have tried Androgel and Natesto in the past and they were awful. Absorption was very inconsistent, while the gel irritates my skin every time. Natesto just didn't work - peak TT was 450s - and it would often end up in the back of my throat tasting bitter.
I'd appreciate your thoughts!
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