Appropriate Starting Dose for Propionate?

I have tried daily doses of 6 to 12mg and have settled for the time being on 8.5mg (roughly equivalent to 10mg of Cypionate), which is quite a bit lower than what you are thinking, but more in line with normal physiological levels (at least I think so). Of course, I won't know for sure until I get off my ass and get tested again.

The tricky part with Prop is that the peaks are higher and troughs lower. If I try to bump up to even 12mg for example, I feel like I drank couple of Red Bulls. Everyone is different though so give it a shot.

This is where @Cataceous blended approach is more ideal.

Quite true that I can't anticipate my response to propionate and perhaps better off starting ultra low. However, with untreatable bipolar, my mood is constantly in flux, even when I sleep. And most days, I'm irritable and hypersexual. Trying lithium for the fifth time. So, I'm prepared for whatever negatives I might experience from propionate.
 

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TRT Hormone Predictor Widget

TRT Hormone Predictor

Predict estradiol, DHT, and free testosterone levels based on total testosterone

⚠️ Medical Disclaimer

This tool provides predictions based on statistical models and should NOT replace professional medical advice. Always consult with your healthcare provider before making any changes to your TRT protocol.

ℹ️ Input Parameters

Normal range: 300-1000 ng/dL

Predicted Hormone Levels

Enter your total testosterone value to see predictions

Results will appear here after calculation

Understanding Your Hormones

Estradiol (E2)

A form of estrogen produced from testosterone. Important for bone health, mood, and libido. Too high can cause side effects; too low can affect well-being.

DHT

Dihydrotestosterone is a potent androgen derived from testosterone. Affects hair growth, prostate health, and masculinization effects.

Free Testosterone

The biologically active form of testosterone not bound to proteins. Directly available for cellular uptake and biological effects.

Scientific Reference

Lakshman KM, Kaplan B, Travison TG, Basaria S, Knapp PE, Singh AB, LaValley MP, Mazer NA, Bhasin S. The effects of injected testosterone dose and age on the conversion of testosterone to estradiol and dihydrotestosterone in young and older men. J Clin Endocrinol Metab. 2010 Aug;95(8):3955-64.

DOI: 10.1210/jc.2010-0102 | PMID: 20534765 | PMCID: PMC2913038

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