Advice on PCT Protocol After 3 Years on TRT?

[Member456]

Hi everyone,

I’m looking for advice on the best way to structure my PCT after being on TRT for about 3 years, specifically whether enclomiphene should overlap with HCG or only after HCG is discontinued.

Here’s my full background and current plan:

TRT History​

• On TRT for ~3 years total
• Started with a 20-week blast, during which I used HCG
• After that, I cruised at 150 mg/week test-cyp for 3 years
• Used HCG inconsistently during this cruise phase (not continuously)

Wanting To Go Off TRT Now​

• I reintroduced HCG at 1300IU EOD on: 11 December 2025
• My last testosterone cypionate injection was on: 23 December 2025
• I began HCG on 11 December before my last test injection to help reawaken the testes

Current Plan PCT Protocol​

• HCG
  • Dose: 1300 IU EOD
  • Started: December 11
  • Planned duration: 8 weeks
  • Last HCG injection: February 6
• Enclomiphene
  • Dose: 25 mg ED
  • Duration: 50 days
  • Planned start: January 15 (uncertain)

Main Question​

My question is about timing and overlap:

• Should I:
  • Wait until the last HCG injection and then start enclomiphene?
  • or
  • Run enclomiphene together with HCG (overlapping from Jan 15 to Feb 6)?

HCG acts directly on the testes while enclomiphene works centrally via LH/FSH signaling, so I’m unsure whether overlapping them would be synergistic or counterproductive for the best possible outcome of natural testosterone recovery. While some say the synergy is better for testicle size and fertility recovery, others say using them seperately is better for overall HPTA recovery and higher test levels post recovery.

Considerations​

• Waiting too long after the last testosterone cypionate injection before starting enclomiphene could leave me feeling significantly hypogonadal once test clears completely out of my system, and that overlapping HCG and enclomiphene might provide a smoother transition rather than an abrupt drop.
• Using HCG and enclomiphene together may be more effective for sperm production and testicular size recovery compared to strictly sequential use, which might be a valid reason for overlapping them instead.

My Main Goal​

• Restoring fertility parameters as effectively as possible
• Restoring testicular function and size as effectively as possible
• Restoring natural testosterone production as effectively as possible
• Avoid unnecessary suppression or a prolonged “crash” during recovery

Any insight, experience, or reasoning would be greatly appreciated.

In order to help others I will update this thread regularly.

Thanks in advance for the help.

 

[Member456]

Today is 15 January and I’m debating whether I should start enclomiphene now or wait until testosterone is fully out of my system (and HCG as well).

I was running testosterone cypionate, with my last injection on 23 December. Given an ~8-day half-life, that puts me at roughly 17% remaining as of today (~3 weeks later).

I also started HCG on 11 December, so I’ve been on it for about 5 weeks now, with ~3 weeks left to go.

Looking for input on timing enclomiphene — start now vs waiting until exogenous test is fully cleared.

@Nelson Vergel

 

[Member456]

@Nelson Vergel !!