Hi everyone,
I’m looking for advice on the best way to structure my PCT after being on TRT for about 3 years, specifically whether enclomiphene should overlap with HCG or start only after HCG is discontinued.
Here’s my full background and current plan:
I understand HCG acts directly on the testes while enclomiphene works centrally via LH/FSH signaling, so I’m unsure whether overlapping them is synergistic or counterproductive.
Any insight, experience, or lab-based reasoning would be greatly appreciated.
Thanks in advance for the help.
I’m looking for advice on the best way to structure my PCT after being on TRT for about 3 years, specifically whether enclomiphene should overlap with HCG or start only after HCG is discontinued.
Here’s my full background and current plan:
TRT History
- On TRT for ~3 years total
- Started with a 20-week blast, during which I used HCG
- After that, I discontinued HCG and stayed on a cruise dose of 150 mg/week testosterone cypionate
- Used HCG inconsistently during the long-term cruise phase (sometimes, but not regularly or continuously)
Coming Off TRT
- Last testosterone cypionate injection: December 23
- I began HCG on December 11 before my last test injection to help reawaken the testes
Current / Planned PCT Protocol
- HCG
- Started: December 11
- Dose: 1300 IU EOD
- Planned duration: 8 weeks
- Last HCG injection: February 6
- Enclomiphene
- Planned start: January 15
- Dose: 25 mg ED
- Duration: 50 days (have 100 tablets of 12.5mg)
- Last dose: March 6
Main Question
My main uncertainty is about timing and overlap:- Is it better to:
- Run enclomiphene concurrently with HCG (overlapping from Jan 15 to Feb 6),
or - Wait until after the final HCG injection and then start enclomiphene alone?
- Run enclomiphene concurrently with HCG (overlapping from Jan 15 to Feb 6),
I understand HCG acts directly on the testes while enclomiphene works centrally via LH/FSH signaling, so I’m unsure whether overlapping them is synergistic or counterproductive.
Additional Considerations
- I’m also concerned that waiting too long after stopping testosterone cypionate before starting enclomiphene could leave me feeling significantly hypogonadal once test clears completely, and that overlapping HCG and enclomiphene might provide a smoother transition rather than an abrupt drop.
- I’ve also read that using HCG and enclomiphene may be more effective for sperm production and testicular size recovery compared to strictly sequential use, which is another reason I’m considering overlap.
Goal
- Restore endogenous testosterone production as effectively as possible
- Support testicular function, fertility parameters, and size
- Avoid unnecessary suppression or a prolonged “crash” during recovery
Any insight, experience, or lab-based reasoning would be greatly appreciated.
Thanks in advance for the help.
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