30 yo, Low Free T?

[kwantiko]

Hello Everyone,

I recently had a my blood drawn. I have some symptoms of low T; decreased libido, poor quality sleep, increased recovery time from sports.

I've had my thyroid and cholesterol checked in other tests, all of which have been normal.

Sex Horm Binding Glob, Serum Sex Horm Binding Glob, Serum: 49.5 nmol/L


What concerns me is the low free T.

Looking for help analyzing these results and for advice on the next course of action.

Thanks,

Alex

 

[Vince Carter]

Well that's a factor of SHBG which can't be manipulated, typically in TRT once you start it can come down a little (who knows, if at all). Low Free T such as you have is really the part of Low T though you get in a difficult spot for treatment whereas most/all will look at the TT and say its good, when its the Free T that is your problem. Some of the better Drs will treat you based on Free T, try Defy Medical and Dr Saya

 

[Systemlord]

Normal thyroid, you going to have to elaborate. Thyroid hormone can be normal and you can still have low thyroid hormones, if Free T3 is lower than midrange but not below the reference ranges, you have low thyroid hormones and symptoms are expected.

There is a variability in the stickiness of SHBG from person to person, your SHBG is very sticky and is getting greedy by holding onto a lot of your testosterone. The estrogen testing (Roche ECLIA methodology) is for females and can overstate a man's estrogen level. The LC/MS/MS method is for males and is more accurate and is designed for men.

You will need TRT as manipulating SHBG is next to impossible, now the only thing you need is a capable doctor that knows what tests are for males and females and how to design a proper TRT protocol designed around your SHBG level.

Estrogen management is critical and any doctor who ignores estrogen should be replaced immediately. There are very few doctors who know how to do TRT well so you must educated yourself because the majority of doctors are not educated in sex hormones.

You would do very well on (60-70mg) twice weekly injections.

 

[kwantiko]

Normal thyroid, you going to have to elaborate. Thyroid hormone can be normal and you can still have low thyroid hormones, if Free T3 is lower than midrange but not below the reference ranges, you have low thyroid hormones and symptoms are expected.

There is a variability in the stickiness of SHBG from person to person, your SHBG is very sticky and is getting greedy by holding onto a lot of your testosterone. The estrogen testing (Roche ECLIA methodology) is for females and can overstate a man's estrogen level. The LC/MS/MS method is for males and is more accurate and is designed for men.

You will need TRT as manipulating SHBG is next to impossible, now the only thing you need is a capable doctor that knows what tests are for males and females and how to design a proper TRT protocol designed around your SHBG level.

Estrogen management is critical and any doctor who ignores estrogen should be replaced immediately. There are very few doctors who know how to do TRT well so you must educated yourself because the majority of doctors are not educated in sex hormones.

You would do very well on (60-70mg) twice weekly injections.

 

[kwantiko]

So you guys think the free T is low enough to consider starting trt?

 

[Systemlord]

No Reverse T3 or antibodies was tested and can explain high TSH since high Reverse T3 blocks Free T3 at the receptors preventing some of that Free T3 from entering your cells. Basically your body only sees a small portion of that Free T3.

TSH over 2.5> is an indication something is wrong.

TRT or BUST, you are below the threshold of where men start experiencing symptoms.