Thoughts on supplementing Pregnenolone and DHEA?

pills. switched to pure-encap brand for both dhea/pregn now.
this is the one supplement you need to buy a trusted brand.
i am also reading that you need to taper it down slowly when down-dosing.
 
I was low on Pregnenolone so doctor had me on 50mg ED. Didn't bring anything up but my e2 and my wife noticed I had a strange odor for those 6 weeks. Stopped taking it and the odor went away, really weird.

How did you feel on Pregnenolone ?
 
DHEA for sure makes me sleep a lot harder than normal. I think it also depresses my mood a bit. I take it on occasion if I feel like I need a solid sleep.

Have not tried pregnenolone, but am interested in it. Would love to hear more about others’ experience with it.
 

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TRT Hormone Predictor Widget

TRT Hormone Predictor

Predict estradiol, DHT, and free testosterone levels based on total testosterone

⚠️ Medical Disclaimer

This tool provides predictions based on statistical models and should NOT replace professional medical advice. Always consult with your healthcare provider before making any changes to your TRT protocol.

ℹ️ Input Parameters

Normal range: 300-1000 ng/dL

Predicted Hormone Levels

Enter your total testosterone value to see predictions

Results will appear here after calculation

Understanding Your Hormones

Estradiol (E2)

A form of estrogen produced from testosterone. Important for bone health, mood, and libido. Too high can cause side effects; too low can affect well-being.

DHT

Dihydrotestosterone is a potent androgen derived from testosterone. Affects hair growth, prostate health, and masculinization effects.

Free Testosterone

The biologically active form of testosterone not bound to proteins. Directly available for cellular uptake and biological effects.

Scientific Reference

Lakshman KM, Kaplan B, Travison TG, Basaria S, Knapp PE, Singh AB, LaValley MP, Mazer NA, Bhasin S. The effects of injected testosterone dose and age on the conversion of testosterone to estradiol and dihydrotestosterone in young and older men. J Clin Endocrinol Metab. 2010 Aug;95(8):3955-64.

DOI: 10.1210/jc.2010-0102 | PMID: 20534765 | PMCID: PMC2913038

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