Anyone ever experience....

CanadaJim

Member
Been on low to average dose test-e since June of this year. Weekly injections 90-100mg. Felt great for the first few months. Libido increased, energy, clarity, over all sense of well-being. The last couple of months have not been as great. Feeling worse than before trt. I'm getting this strange weakness in my arms and legs and my libido has decreased immensely. My sense of well-being has also diminished. I've always been very active with regards to the gym and fitness but lately I really have to coach myself to train. I'm in a rut so to say. I know blood work will tell more of the story and I'm planning on seeing my Doc soon. I was just wondering if anyone else may have had this type of experience and what may have alleviated it. Thanks in advance
 
Been on low to average dose test-e since June of this year. Weekly injections 90-100mg. Felt great for the first few months. Libido increased, energy, clarity, over all sense of well-being. The last couple of months have not been as great. Feeling worse than before trt. I'm getting this strange weakness in my arms and legs and my libido has decreased immensely. My sense of well-being has also diminished. I've always been very active with regards to the gym and fitness but lately I really have to coach myself to train. I'm in a rut so to say. I know blood work will tell more of the story and I'm planning on seeing my Doc soon. I was just wondering if anyone else may have had this type of experience and what may have alleviated it. Thanks in advance

Hard to say without blood work as we have absolutely no idea where your TT/FT/e2 sits at the true trough on once-weekly injections.

The main downfall of injecting larger doses of T once weekly is there can be a large difference in peak--->trough levels let alone blood levels will not be as stable throughout the week which can easily have a negative impact on energy/mood/libido/erectile function/recovery.

The body does not like big swings in T levels.

Even then we have no idea where your SHBG levels sit which is critical as it will have a big impact on the overall effectiveness of a protocol.

You need to know where your SHBG levels sit.

Was it low/normal/high pre-trt and where does it sit as of now as the use of exogenous T especially when injecting larger doses less frequently can have a big impact on lowering SHBG further.
 
Been on low to average dose test-e since June of this year. Weekly injections 90-100mg. Felt great for the first few months. Libido increased, energy, clarity, over all sense of well-being. The last couple of months have not been as great. Feeling worse than before trt. I'm getting this strange weakness in my arms and legs and my libido has decreased immensely. My sense of well-being has also diminished. I've always been very active with regards to the gym and fitness but lately I really have to coach myself to train. I'm in a rut so to say. I know blood work will tell more of the story and I'm planning on seeing my Doc soon. I was just wondering if anyone else may have had this type of experience and what may have alleviated it. Thanks in advance


Keep in mind that the first 6-8 weeks of starting trt let alone when on trt and tweaking dose (increasing/decreasing) can be misleading as levels are in flux during the weeks leading up until blood levels stabilize and even then it can take 2-3 months for the body to adapt to those new levels.

Again blood work is critical when using exogenous T and without such your protocol is sure to fail!

 

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⚠️ Medical Disclaimer

This tool provides predictions based on statistical models and should NOT replace professional medical advice. Always consult with your healthcare provider before making any changes to your TRT protocol.

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Understanding Your Hormones

Estradiol (E2)

A form of estrogen produced from testosterone. Important for bone health, mood, and libido. Too high can cause side effects; too low can affect well-being.

DHT

Dihydrotestosterone is a potent androgen derived from testosterone. Affects hair growth, prostate health, and masculinization effects.

Free Testosterone

The biologically active form of testosterone not bound to proteins. Directly available for cellular uptake and biological effects.

Scientific Reference

Lakshman KM, Kaplan B, Travison TG, Basaria S, Knapp PE, Singh AB, LaValley MP, Mazer NA, Bhasin S. The effects of injected testosterone dose and age on the conversion of testosterone to estradiol and dihydrotestosterone in young and older men. J Clin Endocrinol Metab. 2010 Aug;95(8):3955-64.

DOI: 10.1210/jc.2010-0102 | PMID: 20534765 | PMCID: PMC2913038

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