GONADOERALIN VS HCG

So far no evidence has been presented to show that gonadorelin can be used as a direct replacement for hCG. There are theoretical reasons to be skeptical, including the rapid and pulsatile nature of endogenous GnRH production, and the suppressive effects of TRT on the pituitary. I've shown that with a rigorous protocol gonadorelin can restore gonadotropins under TRT. But while these results are interesting and show some promise for improving TRT, the method is likely to be impractical for most.
 
So why cant i get HCG anymore? ...

Some details here:

... Would it be better to not use gonadorelin while on TRT?
This use should be considered experimental. My hunch is that at physiological doses there may be some benefits to it even if gonadotropins are not produced. But if you don't get gonadotropins then you don't have the benefits you'd get with hCG. Furthermore, the protocols being put forth by clinics offering gonadorelin are not remotely physiological.
 

hCG Mixing Calculator

HCG Mixing Protocol Calculator

TRT Hormone Predictor Widget

TRT Hormone Predictor

Predict estradiol, DHT, and free testosterone levels based on total testosterone

⚠️ Medical Disclaimer

This tool provides predictions based on statistical models and should NOT replace professional medical advice. Always consult with your healthcare provider before making any changes to your TRT protocol.

ℹ️ Input Parameters

Normal range: 300-1000 ng/dL

Predicted Hormone Levels

Enter your total testosterone value to see predictions

Results will appear here after calculation

Understanding Your Hormones

Estradiol (E2)

A form of estrogen produced from testosterone. Important for bone health, mood, and libido. Too high can cause side effects; too low can affect well-being.

DHT

Dihydrotestosterone is a potent androgen derived from testosterone. Affects hair growth, prostate health, and masculinization effects.

Free Testosterone

The biologically active form of testosterone not bound to proteins. Directly available for cellular uptake and biological effects.

Scientific Reference

Lakshman KM, Kaplan B, Travison TG, Basaria S, Knapp PE, Singh AB, LaValley MP, Mazer NA, Bhasin S. The effects of injected testosterone dose and age on the conversion of testosterone to estradiol and dihydrotestosterone in young and older men. J Clin Endocrinol Metab. 2010 Aug;95(8):3955-64.

DOI: 10.1210/jc.2010-0102 | PMID: 20534765 | PMCID: PMC2913038

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