Gene's Nitric Oxide Stack

Many have used this stack for massive hard pumps in the gym, significant vascularity and excellent erectile function not discounting the health benefits. If you're looking for any of these benefits and more...give it a try!

Nitric Oxide Stack
Bed Time
5 mg of Tadalafil (Cialis)
3000 mg of L-Arginine
1500 mg of L-Citrulline
50 mg of Pycnogenol
150 mg of Icariin (Horny Goat Weed)
1 mg of Doxazosin (Alpha Blocker)


Morning
3000 mg of L-Arginine
1500 mg of L-Citrulline
50 mg of Pycnogenol
150 mg of Icariin (Horny Goat Weed)


nitric oxide excelmale.webp

Afternoon
5 mg of Tadalafil (Cialis)
3000 mg of L-Arginine
1500 mg of L-Citrulline
50 mg of Pycnogenol
150 mg of Icariin (Horny Goat Weed)
1 mg of Doxazosin (Alpha Blocker)



More Than a Muscle Pump: The Surprising Science of the Nitric Oxide Stack

In the biohacking world, we often chase complex peptides or experimental compounds, but we frequently overlook the most fundamental currency of life: blood flow. In the quest for longevity, systemic vascular efficiency is the baseline upon which all other health markers are built. As we age, our ability to maintain vasodilatory capacity diminishes, impacting everything from cognitive sharpness to metabolic health. "Gene’s Nitric Oxide Stack," a protocol born and refined within the ExcelMale community, has emerged as a definitive solution for men seeking to optimize this system. This isn't just a gym supplement routine; it is a sophisticated approach to anti-aging that leverages amino acids and targeted pharmaceutical interventions to restore the body’s most vital delivery mechanism.

Beyond the Mirror: The Science of the Sustained Pump​

For the average gym-goer, the "pump" is a transient aesthetic goal—a fleeting moment of muscle fullness. However, for a longevity specialist, a "harder pump" and increased vascularity are indicators of high-functioning endothelial health. The Nitric Oxide Stack is engineered to produce a state of vasodilation that doesn't simply vanish when you rack the weights.

By optimizing the nitric oxide signaling pathway, this protocol facilitates a sustained pump that carries through your daily life. This is a critical distinction: the visual vascularity is a proxy for your body’s ability to keep its "pipes" open. When you maintain that fullness hours after a workout, you are essentially providing proof of concept that your circulatory system is operating at peak efficiency, ensuring constant nutrient delivery to peripheral tissues.

The Foundation of Performance: Hard Science for Sexual Vitality​

One of the most immediate benefits of systemic vasodilation is the restoration of sexual function. From a clinical perspective, erection quality is often the "canary in the coal mine" for cardiovascular health. Because the Nitric Oxide Stack focuses on the root physiological requirements of performance—blood flow and retention—it provides a robust alternative to temporary fixes.

A Serious Solution for Erection Quality and Duration

This stack addresses both the quality and the duration of erections with clinical precision. For men navigating the aging process, this is not a matter of vanity, but of maintaining vital physiological function. By ensuring the vascular system can respond effectively to neurological signals, the protocol allows for a level of performance that many mistakenly believe is lost to time.

The Ultimate Nootropic: Future-Proofing the Neocortex​

Perhaps the most compelling argument for nitric oxide optimization is the "bodybuilder to brain health" pipeline. While most men start this stack for its physical benefits, they are unknowingly deploying a powerful shield against age-related cognitive decline. As we age, the micro-vasculature within the brain tends to narrow and tighten, a process that starves the brain of oxygen and is a primary driver of age-related dementia.

The stack acts as a nootropic by ensuring that the brain's smallest vessels remain dilated and resilient. This ensures that the neocortex and other critical regions receive a constant supply of the nutrients required for cognitive longevity. As the source material highlights:

"by increasing nitric oxide and getting that vascular dilation we're getting oxygen blood and nutrients in the areas of the brain that can provide us with a great anti-aging benefit in terms of neurological health."

The irony is profound: a protocol often associated with the bicep curl may actually be one of your most effective tools for protecting your mind.

Systemic Management: Blood Pressure and Prostate Function​

The benefits of the stack extend into the deeper mechanics of men’s health, specifically regarding the relaxation of smooth muscle tissue. This is particularly relevant for Benign Prostate Hyperplasia (BPH) and blood pressure management. Nitric oxide serves as a signal for these tissues to relax, directly easing the "inability to ease the problems" that typically characterize age-related prostate issues.

The secondary physiological advantages of this systemic relaxation include:

  • Vascular Tension Reduction: Significant support for maintaining healthy blood pressure levels by reducing resistance within the arterial walls.
  • Prostate Relief: Improvement in quality of life by relaxing the prostatic smooth muscle, easing the mechanical symptoms of BPH.
  • Reduced Cardiac Load: By improving systemic flow, the heart is not required to pump against the same level of resistance, preserving cardiovascular longevity.

The Future of Your Vascular Health​

"Gene’s Nitric Oxide Stack" is far from a theoretical exercise; it is a "living protocol" backed by years of community peer-review within the ExcelMale community. The "enormously long" and widely viewed thread on ExcelMale.com serves as a testament to the real-world efficacy of this stack, offering a repository of shared experiences and optimization strategies.

This multi-front approach to anti-aging represents the best of biohacking: using fundamental biological pathways to solve complex aging problems. By focusing on the delivery system itself, we can protect our brains, our hearts, and our vitality simultaneously.

If blood flow is the delivery system for every nutrient your body needs, what happens to your longevity when you finally optimize that system?


More on Nitric Oxide in Men:

Nitric Oxide Pages
 
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OH we are not back peddling a bit are we Gene? haha

Do you need to edit your first post to ad you probably should start with Sub 10% bf ?

Don't go popping one of those big vessels I'm just messing with you my friend.

We'll I am pretty lean yes but the stack is much more beneficial for health then just seeing vascularity...much more;-)
 
Here are some of my results on the stack.. My body fat is not super low and I don't have pumps yet in any of these pics... The 2 pics that are not gym pics were actually taken right before bed... GeneStack3.webp Genestack1.webp Genestack2.webp
 
Having low body fat levels will always enhance ones vascularity as when body fat levels are higher vascularity will be masked to a certain degree. You will notice in a previous thread Vince is very lean as pics he posted show his clearly defined abs. Combining a diet that will enhance fat loss with Genes protocol will give the best results. Sub 10% bf is when you will really start to notice vascularity.

For some reason I have a lot of vascularity but there is no way I am close to 10%... Not sure what drives this with me but I have to attribute most of it to the stack...
 
For some reason I have a lot of vascularity but there is no way I am close to 10%... Not sure what drives this with me but I have to attribute most of it to the stack...

Are you sure it is adipose and you are not just retaining water as you look fairly lean to me in your pic? What method of testing did you use to determine your body fat %, hopefully not BIA(bioelectrical impedance) as that method is not as accurate as skin fold calipers or the gold standard DEXA. I think the main benefits of Genes stack is the positive impact it will have on ones endothelial/vascular function/health and of course it will increase ones vascularity without dieting (for those with higher body fat levels) but vascularity will be enhanced greatly in those whom attain the single digit body fat % and if one is seeking to use Genes stack for the sole purpose of enhancing vascularity it would seem to me that achieving lower body fat levels combined with Genes stack would give the most bang for the buck and hitting sub 10% body fat visually the veins will POP!
 
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Are you sure it is adipose and you are not just retaining water as you look fairly lean to me in your pic? What method of testing did you use to determine your body fat %, hopefully not BIA(bioelectrical impedance) as that method is not as accurate as skin fold calipers or the gold standard DEXA.

Yeah I use the handheld deal... You key in your age, height ,weight and hold on with each hand. It pretty consistently says I am14-16% body fat.... For whatever reason I am always vascular right now to the point my wife thinks it gross (but I like it). I am religious with the stack but it is slightly altered for me... I wonder if heavy lifting also contributes to vascularity and if genetics play a role too?
 
Here are some of my results on the stack.. My body fat is not super low and I don't have pumps yet in any of these pics... The 2 pics that are not gym pics were actually taken right before bed... View attachment 4207View attachment 4208View attachment 4209


Some stats on me to put it in perspective... Height 5'11'', weight 230, bicep 19 inches cold, waist 33 inches. The way I train is heavy weight with a lot of reps... For example when I do triceps I do 225 for reps of 25-30. On chest day I will do 20-25 sets and here is a sampe of what I do on flat bench-

Set 1. 135 30 reps
Set 2. 225 20 reps
Set 3. 275 15 reps
Set 4. 315 12 reps
Set 5. 365 8 reps
Set 6. 405 6 reps
Set 7. 315 15 reps
Set 8. 225 30 reps

Move to incline...
 
Some stats on me to put it in perspective... Height 5'11'', weight 230, bicep 19 inches cold, waist 33 inches. The way I train is heavy weight with a lot of reps... For example when I do triceps I do 225 for reps of 25-30. On chest day I will do 20-25 sets and here is a sampe of what I do on flat bench-

Set 1. 135 30 reps
Set 2. 225 20 reps
Set 3. 275 15 reps
Set 4. 315 12 reps
Set 5. 365 8 reps
Set 6. 405 6 reps
Set 7. 315 15 reps
Set 8. 225 30 reps

Move to incline...

That is a high volume good poundage............think I would over train using that volume as I tend to do my warm up sets and than use 6x6 heavy weight every set. Genetics definitely plays a role in vascularity and as far as training lower rep/heavy weight may enhance vascularity but I would say higher reps/lighter weight shorter rest periods is more prone to creating new blood vessels/capillaries.
 
That is a high volume good poundage............think I would over train using that volume as I tend to do my warm up sets and than use 6x6 heavy weight every set. Genetics definitely plays a role in vascularity and as far as training lower rep/heavy weight may enhance vascularity but I would say higher reps/lighter weight shorter rest periods is more prone to creating new blood vessels/capillaries.

I do those weights and reps with little rest time maybe 1 minute max... It's just the way I have trained forever. CT fletcher posted a youtube video doing 225 for 400 reps in a little less than 2 hours, I did it in an hour and 15 minutes :).... I also just work each body part once per week...
 
For some reason I have a lot of vascularity but there is no way I am close to 10%... Not sure what drives this with me but I have to attribute most of it to the stack...
Hi Loki, Do you use Gene's stack? Have you changed any of the ingredient or frequency you take them?
 
With 29 pages in this thread I'll have to ask instead of reading it all...
Loki, are you on trt, or more?
What is your protocol like?
Do you do any cardio at all?
 
Hi Loki, Do you use Gene's stack? Have you changed any of the ingredient or frequency you take them?

I take the arginine, pycnogenol, citrulline 3 times a day at the recommended amounts. I take 5MG of daily cialis. That's my modified version. I don't take preworkout for every work out but when I take pre most of the ingredients are in the pre so I skip 1 of the 3 doses that day. I love the stack !!!
 
With 29 pages in this thread I'll have to ask instead of reading it all...
Loki, are you on trt, or more?
What is your protocol like?
Do you do any cardio at all?

I am just on TRT. Here is my protocol -

70MG Test Cyp twice per week
400 units HCG 3 times per week
50MG of test cream daily
Daily stack

No cardio :)

I eat clean and train on weights (not much rest so heart rate is very elevated) 6 times per week.
 
I am just on TRT. Here is my protocol -

70MG Test Cyp twice per week
400 units HCG 3 times per week
50MG of test cream daily
Daily stack

No cardio :)

I eat clean and train on weights (not much rest so heart rate is very elevated) 6 times per week.

Thx for the follow up.
Nice job job man, keep up the hard work.
 
Unfortunately I can not take Arginine because it gives me bad diarrhea so I just use Citrulline at 4 grams a day total. I tried Black Maca for a bit but that killed my stomach and after more research did not like what I read....

My stack is similar to this but doses are a little different and I use bulk supplements Pine Bark instead of Pycnogenol to save a little money. I have added a couple other things like garlic, zinc, Vit C and D which seem to help, overall I have seen a big improvement (I have taken Zinc and D my whole adult life I just upped my D intake). Recently added Tongkat Ali extract at 80mg and 6mg of Boron and that has been great, I am now wondering if my Test levels were down and maybe this brought me back up. I did use steroids in my 20s and I am now 36 and wondering if that effected me negatively. I don't use steroids anymore, I haven't in years and wont again. I still weight train but not heavy because of injuries to my shoulder and neck plus my lower back acts up sometimes, fun fun.....

Any benefit to taking the Citrulline and HGW 3 times a day instead of 2 which is what I am currently doing? Would adding another 2 grams of Citrulline mid day be beneficial or stick with what I am doing? I also just started doing the Pine Bark once a day instead of twice at half the dose because I feel like that is messing with my stomach for some reason. Lastly it is very hard to find the answer to my question regarding HGW, is it fine to stay on this long term without breaks? (I use the bulk supps 10%)
 
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Unfortunately I can not take Arginine because it gives me bad diarrhea so I just use Citrulline at 4 grams a day total. I tried Black Maca for a bit but that killed my stomach and after more research did not like what I read....

My stack is similar to this but doses are a little different and I use bulk supplements Pine Bark instead of Pycnogenol to save a little money. I have added a couple other things like garlic, zinc, Vit C and D which seem to help, overall I have seen a big improvement (I have taken Zinc and D my whole adult life I just upped my D intake). Recently added Tongkat Ali extract at 80mg and 6mg of Boron and that has been great, I am now wondering if my Test levels were down and maybe this brought me back up. I did use steroids in my 20s and I am now 36 and wondering if that effected me negatively. I don't use steroids anymore, I haven't in years and wont again. I still weight train but not heavy because of injuries to my shoulder and neck plus my lower back acts up sometimes, fun fun.....

Any benefit to taking the Citrulline and HGW 3 times a day instead of 2 which is what I am currently doing? Would adding another 2 grams of Citrulline mid day be beneficial or stick with what I am doing? I also just started doing the Pine Bark once a day instead of twice at half the dose because I feel like that is messing with my stomach for some reason. Lastly it is very hard to find the answer to my question regarding HGW, is it fine to stay on this long term without breaks? (I use the bulk supps 10%)

Hi Chris you did not mention how much Tadalafil and Doxazsin you are taking with this stack.

But remember, the foundation of my stack is the PDE5i Tadalafil and alpha blocker Doxazsin; these are two powerhouses.

Everything else is just supplemental and supporting. -Gene
 
Some stats on me to put it in perspective... Height 5'11'', weight 230, bicep 19 inches cold, waist 33 inches. The way I train is heavy weight with a lot of reps... For example when I do triceps I do 225 for reps of 25-30. On chest day I will do 20-25 sets and here is a sampe of what I do on flat bench-

Set 1. 135 30 reps
Set 2. 225 20 reps
Set 3. 275 15 reps
Set 4. 315 12 reps
Set 5. 365 8 reps
Set 6. 405 6 reps
Set 7. 315 15 reps
Set 8. 225 30 reps

Move to incline...
Great pictures, you should think about posting some under the Before and After Pictures - Testimonials thread
 

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