Gene's Nitric Oxide Stack

Many have used this stack for massive hard pumps in the gym, significant vascularity and excellent erectile function not discounting the health benefits. If you're looking for any of these benefits and more...give it a try!

Nitric Oxide Stack
Bed Time
5 mg of Tadalafil (Cialis)
3000 mg of L-Arginine
1500 mg of L-Citrulline
50 mg of Pycnogenol
150 mg of Icariin (Horny Goat Weed)
1 mg of Doxazosin (Alpha Blocker)


Morning
3000 mg of L-Arginine
1500 mg of L-Citrulline
50 mg of Pycnogenol
150 mg of Icariin (Horny Goat Weed)

Afternoon
5 mg of Tadalafil (Cialis)
3000 mg of L-Arginine
1500 mg of L-Citrulline
50 mg of Pycnogenol
150 mg of Icariin (Horny Goat Weed)
1 mg of Doxazosin (Alpha Blocker)

More Than a Muscle Pump: The Surprising Science of the Nitric Oxide Stack​

In the biohacking world, we often chase complex peptides or experimental compounds, but we frequently overlook the most fundamental currency of life: blood flow. In the quest for longevity, systemic vascular efficiency is the baseline upon which all other health markers are built. As we age, our ability to maintain vasodilatory capacity diminishes, impacting everything from cognitive sharpness to metabolic health. "Gene’s Nitric Oxide Stack," a protocol born and refined within the ExcelMale community, has emerged as a definitive solution for men seeking to optimize this system. This isn't just a gym supplement routine; it is a sophisticated approach to anti-aging that leverages amino acids and targeted pharmaceutical interventions to restore the body’s most vital delivery mechanism.

Beyond the Mirror: The Science of the Sustained Pump​

For the average gym-goer, the "pump" is a transient aesthetic goal—a fleeting moment of muscle fullness. However, for a longevity specialist, a "harder pump" and increased vascularity are indicators of high-functioning endothelial health. The Nitric Oxide Stack is engineered to produce a state of vasodilation that doesn't simply vanish when you rack the weights.

By optimizing the nitric oxide signaling pathway, this protocol facilitates a sustained pump that carries through your daily life. This is a critical distinction: the visual vascularity is a proxy for your body’s ability to keep its "pipes" open. When you maintain that fullness hours after a workout, you are essentially providing proof of concept that your circulatory system is operating at peak efficiency, ensuring constant nutrient delivery to peripheral tissues.

The Foundation of Performance: Hard Science for Sexual Vitality​

One of the most immediate benefits of systemic vasodilation is the restoration of sexual function. From a clinical perspective, erection quality is often the "canary in the coal mine" for cardiovascular health. Because the Nitric Oxide Stack focuses on the root physiological requirements of performance—blood flow and retention—it provides a robust alternative to temporary fixes.

A Serious Solution for Erection Quality and Duration

This stack addresses both the quality and the duration of erections with clinical precision. For men navigating the aging process, this is not a matter of vanity, but of maintaining vital physiological function. By ensuring the vascular system can respond effectively to neurological signals, the protocol allows for a level of performance that many mistakenly believe is lost to time.

The Ultimate Nootropic: Future-Proofing the Neocortex​

Perhaps the most compelling argument for nitric oxide optimization is the "bodybuilder to brain health" pipeline. While most men start this stack for its physical benefits, they are unknowingly deploying a powerful shield against age-related cognitive decline. As we age, the micro-vasculature within the brain tends to narrow and tighten, a process that starves the brain of oxygen and is a primary driver of age-related dementia.

The stack acts as a nootropic by ensuring that the brain's smallest vessels remain dilated and resilient. This ensures that the neocortex and other critical regions receive a constant supply of the nutrients required for cognitive longevity. As the source material highlights:

"by increasing nitric oxide and getting that vascular dilation we're getting oxygen blood and nutrients in the areas of the brain that can provide us with a great anti-aging benefit in terms of neurological health."

The irony is profound: a protocol often associated with the bicep curl may actually be one of your most effective tools for protecting your mind.

Systemic Management: Blood Pressure and Prostate Function​

The benefits of the stack extend into the deeper mechanics of men’s health, specifically regarding the relaxation of smooth muscle tissue. This is particularly relevant for Benign Prostate Hyperplasia (BPH) and blood pressure management. Nitric oxide serves as a signal for these tissues to relax, directly easing the "inability to ease the problems" that typically characterize age-related prostate issues.

The secondary physiological advantages of this systemic relaxation include:

• Vascular Tension Reduction: Significant support for maintaining healthy blood pressure levels by reducing resistance within the arterial walls.
• Prostate Relief: Improvement in quality of life by relaxing the prostatic smooth muscle, easing the mechanical symptoms of BPH.
• Reduced Cardiac Load: By improving systemic flow, the heart is not required to pump against the same level of resistance, preserving cardiovascular longevity.

The Future of Your Vascular Health​

"Gene’s Nitric Oxide Stack" is far from a theoretical exercise; it is a "living protocol" backed by years of community peer-review within the ExcelMale community. The "enormously long" and widely viewed thread on ExcelMale.com serves as a testament to the real-world efficacy of this stack, offering a repository of shared experiences and optimization strategies.

This multi-front approach to anti-aging represents the best of biohacking: using fundamental biological pathways to solve complex aging problems. By focusing on the delivery system itself, we can protect our brains, our hearts, and our vitality simultaneously.

If blood flow is the delivery system for every nutrient your body needs, what happens to your longevity when you finally optimize that system?


More on Nitric Oxide in Men:

Nitric Oxide Pages

 

Many have used this stack for massive hard pumps in the gym, significant vascularity and excellent erectile function not discounting the health benefits. If you're looking for any of these benefits and more...give it a try!

Nitric Oxide Stack
Bed Time
5 mg of Tadalafil (Cialis)
3000 mg of L-Arginine
1500 mg of L-Citrulline
50 mg of Pycnogenol
150 mg of Icariin (Horny Goat Weed)
1 mg of Doxazosin (Alpha Blocker)


Morning
3000 mg of L-Arginine
1500 mg of L-Citrulline
50 mg of Pycnogenol
150 mg of Icariin (Horny Goat Weed)



Afternoon
5 mg of Tadalafil (Cialis)
3000 mg of L-Arginine
1500 mg of L-Citrulline
50 mg of Pycnogenol
150 mg of Icariin (Horny Goat Weed)
1 mg of Doxazosin (Alpha Blocker)

Most Important Testosterone, HCG, Anastrozole, Trimix, etc Fact Sheets on ExcelMale

Hello Gene, I wanted to try your Nitric Oxide Stack however I am a little worried at my age of 64 and I am not a body builder.
I do go to a gym 4 days a week however my workouts are general fitness/core based.
Do you have a Gene's Nitric Oxide Stack LITE? For those of use who would like to get a little more vascular.

 

Along with? I'm sure that some one does but this stack itself with a little added caffeine and Beta Alanine would be a superior pre-workout.

^^^^Exactly!

 

Hello Gene, I wanted to try your Nitric Oxide Stack however I am a little worried at my age of 64 and I am not a body builder.
I do go to a gym 4 days a week however my workouts are general fitness/core based.
Do you have a Gene's Nitric Oxide Stack LITE? For those of use who would like to get a little more vascular.

I'm not sure what your concerns are? In fact, this stack for the aging male is an important anti-aging protocol.

As we age the small blood vessels and capillaries get smaller and tighter and one reason is a major contributor to age related dementia. By increasing NO we are essentially opening up all these blood vessels to allow more oxygen and nutrients into places in the body that otherwise would be starved. This health benefit alone is worth using the stack besides the health benefits to heart disease, hypertension, erectile quality and harder longer pumps in the gym.

There is much written on this a simple Google search will reveal much more then I can put into a post here.

Follow this link: https://www.google.com/search?q=nit...0....0...1..64.psy-ab..0.0.0....0.kqGXBii8RZA

 

I'm not sure what your concerns are? In fact, this stack for the aging male is an important anti-aging protocol.

As we age the small blood vessels and capillaries get smaller and tighter and one reason is a major contributor to age related dementia. By increasing NO we are essentially opening up all these blood vessels to allow more oxygen and nutrients into places in the body that otherwise would be starved. This health benefit alone is worth using the stack besides the health benefits to heart disease, hypertension, erectile quality and harder longer pumps in the gym.

There is much written on this a simple Google search will reveal much more then I can put into a post here.

Being new to this N O I just though I should ask before just jumping in.
In researching Tadalafil, 10mg/24 hrs seems like a lot. If I read it right it stays in your system for 3 day so in 72 hours you are now running 30mg.
Now my PCP says take 40mg when its fun night with the wife.
I don't want to take this NO stack and end up walk around all day doing my interpertation of a hand towel rack, haha.

 

Being new to this N O I just though I should ask before just jumping in.
In researching Tadalafil, 10mg/24 hrs seems like a lot. If I read it right it stays in your system for 3 day so in 72 hours you are now running 30mg.
Now my PCP says take 40mg when its fun night with the wife.
I don't want to take this NO stack and end up walk around all day doing my interpertation of a hand towel rack, haha.

When have you ever taken a drug over three days time and it added up like that? Who told you this happens like that?

 

Being new to this N O I just though I should ask before just jumping in.
In researching Tadalafil, 10mg/24 hrs seems like a lot. If I read it right it stays in your system for 3 day so in 72 hours you are now running 30mg.
Now my PCP says take 40mg when its fun night with the wife.
I don't want to take this NO stack and end up walk around all day doing my interpertation of a hand towel rack, haha.

After roughly nine hours the Tadalafil starts to eliminate and around hour 17-18 the first dose is at it's half life. So if you let your 3rd dose hit it's peak you are looking at 21MG in the system and falling each hour after this...

 

After roughly nine hours the Tadalafil starts to eliminate and around hour 17-18 the first dose is at it's half life. So if you let your 3rd dose hit it's peak you are looking at 21MG in the system and falling each hour after this...

Thanks Loki. Is 21 a lot for someone who does not take Tadalafil daily?

Let me try and ask the question a different way. I am looking for this lvl of vasculation.

not this lvl.

So can I cut this stack in half and see any results? I know nothing in medicine is linear.

 

That is what I would do, cut it in half and see how you feel. Then adjust upward or downward based on your research and your body's feedback.

 

The main ingredient there is Citrulline, use that 3x a day. The rest of it is all synergistic but if you're looking for a simplistic and/or low cost start point, go with Citrulline. This is about Nitric Oxide and Citrulline is the most potent ingredient you can use.

 

From a pure research perspective, there's hasn't been much research on it, Paco. Of course there are a lot of good supporting articles on these amino acids that point to their benefits.

But remember, the foundation of my stack is the PDE5i Tadalafil and alpha blocker Doxazsin; these are two powerhouses.

Everything else is just supplemental and supporting.

snip...

The main ingredient there is Citrulline, use that 3x a day. The rest of it is all synergistic but if you're looking for a simplistic and/or low cost start point, go with Citrulline. This is about Nitric Oxide and Citrulline is the most potent ingredient you can use.

Hrmmm you are confusing me Vince. According to Gene Citrulline is not the main ingredient in this NO stack.

 

I clearly said simplistic and/or low cost route...Citrulline is the basis and is unequivocally the NO donor of choice. Gene cites pharmaceutical drugs. Opinions vary. But if you're confused, buy all that stuff, go see your Dr and get the scripts and take the drugs.

 

That is what I would do, cut it in half and see how you feel. Then adjust upward or downward based on your research and your body's feedback.

Thanks Saul,
This is exactly or close to what I will try based on the suppliment mg values I can find.
All the suppliments and prescrips have been ordered. Here's what I ended up with.

Gene's.................................................My reduced NO Stack
===================================================
5 mg of Tadalafil (Cialis).........................2.5 mg of Tadalafil (Cialis)
3000 mg of L-Arginine............................750mg L-Arginine
1500 mg of L-Citrulline..........................250mg L-Citrulline
50 mg of Pycnogenol..............................30mg Pycnogenol
150 mg of Icariin (Horny Goat Weed)..... 100mg Icariins
1 mg of Doxazosin (Alpha Blocker).............0.5 mg Doxazosin

I also only plan to take these 2x in 24 hours no mid day pills.

EDIT: I am not very good at this whole selfie thing but here is what I have to start with. Gene if you have no issues I will report back with a progress picture in 30/60 days post getting the supplies.

If you think this will dilute your thread I can start another if anyone is interested in following this experiment.

Taken October 10th 2017 pre N O Lite Stack.

 

"I can start another if anyone is interested in following this experiment."

Yes, I think that would be nice to start a new thread. I would be very interested in following along.

 

Thanks Saul,
This is exactly or close to what I will try based on the suppliment mg values I can find.
All the suppliments and prescrips have been ordered. Here's what I ended up with.

Gene's.................................................My reduced NO Stack
===================================================
5 mg of Tadalafil (Cialis).........................2.5 mg of Tadalafil (Cialis)
3000 mg of L-Arginine............................750mg L-Arginine
1500 mg of L-Citrulline..........................250mg L-Citrulline
50 mg of Pycnogenol..............................30mg Pycnogenol
150 mg of Icariin (Horny Goat Weed)..... 100mg Icariins
1 mg of Doxazosin (Alpha Blocker).............0.5 mg Doxazosin

I also only plan to take these 2x in 24 hours no mid day pills.

EDIT: I am not very good at this whole selfie thing but here is what I have to start with. Gene if you have no issues I will report back with a progress picture in 30/60 days post getting the supplies.

If you think this will dilute your thread I can start another if anyone is interested in following this experiment.

Taken October 10th 2017 pre N O Lite Stack.

Looking forward to it!

 

Looking forward to it!

OK today is day one. All meds and supplements are in. I will take my first stack tonight at bed time it will be:
2.5 mg of Tadalafil
750mg L-Arginine
250mg L-Citrulline
30mg Pycnogenol
100mg Icariins
0.5 mg Doxazosin

I'll take the same dose right after breakfast. NO mid day supplements.

A couple base line numbers to note.
Morning and evening blood pressure.

Comments suggestions welcome.
I did just do blood work on 8/31 and will be doing blood again late Nov. I can post the 8/31 if its relevant.

If you guys can't tell I am a retired Aerospace Engineer BS ME with an MBA 28 years with Lockheed.
I love datalogging and documenting, it's in my blood.

 

Thanks Loki. Is 21 a lot for someone who does not take Tadalafil daily?

Let me try and ask the question a different way. I am looking for this lvl of vasculation.

not this lvl.

So can I cut this stack in half and see any results? I know nothing in medicine is linear.

Having low body fat levels will always enhance ones vascularity as when body fat levels are higher vascularity will be masked to a certain degree. You will notice in a previous thread Vince is very lean as pics he posted show his clearly defined abs. Combining a diet that will enhance fat loss with Genes protocol will give the best results. Sub 10% bf is when you will really start to notice vascularity.

 

Having low body fat levels will always enhance ones vascularity as when body fat levels are higher vascularity will be masked to a certain degree. You will notice in a previous thread Vince is very lean as pics he posted show his clearly defined abs. Combining a diet that will enhance fat loss with Genes protocol will give the best results. Sub 10% bf is when you will really start to notice vascularity.

Very very well said...thank you.

 

Having low body fat levels will always enhance ones vascularity as when body fat levels are higher vascularity will be masked to a certain degree. You will notice in a previous thread Vince is very lean as pics he posted show his clearly defined abs. Combining a diet that will enhance fat loss with Genes protocol will give the best results. Sub 10% bf is when you will really start to notice vascularity.

Thanks Madman, I am working on my weight. I have cleaned up my diet a lot starting back in January 2016
Here's a typical meal plan for 24 hours.
Note: the large lunch is because i was Mtn Biking ~20 miles over 3 hours.
Peanutbutter/beef jerky/Pistachios are my staples while riding. I don't eat them on gym days.

I ride 14-20miles 3 days a week year round and spend 3 hours in the Gym on the opposite days. No real body building just general fitness/core exersize/swimming. My HR monitor reports 500-600 calories burned per day. My base caloric diet is 1650 but if I burn 600 cal on my bike I EAT THEM. haha

Please keep the tips coming and thanks again. I always look forward to reading your posts here on the forum.

 

Very very well said...thank you.

OH we are not back peddling a bit are we Gene? haha

Do you need to edit your first post to ad you probably should start with Sub 10% bf ?

Don't go popping one of those big vessels I'm just messing with you my friend.

 

That diet still needs some work