Testosterone

Pharmacogenetics of testosterone replacement therapy

Mar 03

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Understanding How Androgens (Male Hormones) Work in the Body Androgens, such as testosterone, play a key role in male development and overall health. However, their effects vary from person to person due to differences in how the body responds to...

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Men's Response to Testosterone Depends on their CAG Repeats in Their AR Gene.

Mar 01

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Androgen Sensitivity: Beyond the Well-Known © Irina A. Khripun*, Sergey V. Vorobyev Rostov State Medical University, Rostov-on-Don, Russia The gonadal and extragonadal effects of testosterone in men have been actively studied in recent...

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FDA issues class-wide labeling changes for testosterone products

Feb 28

https://www.fda.gov/drugs/drug-safety-and-availability/fda-issues-class-wide-labeling-changes-testosterone-products [2/28/2025] Today, FDA informed sponsors of testosterone products about new labeling changes following the agency’s review of...

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Potential Causes of Low Testosterone

Jan 31

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Testosterone is more than just a sex hormone. It plays a crucial role in a range of physiological processes, including the development of muscle mass, bone density, and even the modulation of blood sugar levels. While high levels of testosterone...

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Management of Erythrocytosis in Men Receiving TRT

Jan 23

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Management of Erythrocytosis in Men Receiving Testosterone Therapy: Clinical Consultation Guide (2022) Pranjal Agrawal, Sajya M. Singh, Taylor Kohn 1. Introduction Testosterone deficiency, previously known as male hypogonadism, affects...

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Testosterone Cypionate and Nandrolone Decanoate

Jan 19

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Hello, I'm writing this post to gather opinion and insight from others on a similar path. I've been prescribed Testosterone for two years. Due to various reasons, adding Nandrolone Decanoate as an adjunct has been suggested by my provider...

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Compounded Hormone Products for Men: A Review by Shaun Noorian

Jan 07

In this conversation, Nelson Vergel and Shaun Noorian discuss the various options available for men's hormonal treatments, focusing on hormone replacement therapy, the role of compounding pharmacies, and the importance of personalized medicine...

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TRT Before and After: Real Transformations

Dec 27

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TRT Before and After: See Real Transformations Key Highlights Explore the amazing changes people go through before and after starting Testosterone Replacement Therapy (TRT). Understand how TRT can greatly improve life quality by fixing low...

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Updates on Testosterone Deficiency in Men Living With HIV and the Cardiovascular Implications

Dec 27

Fig. 1 Proposed mechanism of testosterone and HIV on the systemic vasculature. This figure exemplifies the similarities of both TD and HIV on the vascular system and therefore the potential to enhance CVD risk. Both conditions lead to vessel...

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Estradiol Testing in Men

Dec 25

https://myadlm.org/advocacy-and-outreach/optimal-testing-guide-to-lab-test-utilization/a-f/estradiol-testing-in-men Estradiol in Men: Optimal Testing Recommendations Measurement of estradiol in men (and children) should be performed by a...

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Can Testosterone Induce Blood Clots and Thrombosis? Interview with Dr Charles Glueck

Dec 18

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In my work collecting information for ExcelMale.com, I review abstracts daily on latest studies related to testosterone, men's health, nutrition, and more. I am always looking for studies that stand out and are no just repetitions of what we...

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COMBINED CLOMIPHENE AND LOW-DOSE KYZATREX (ORAL TESTOSTERONE) THERAPY IN HYPOGONADAL MEN: A CASE SERIE

Dec 18

Abstract Introduction Clomiphene is often used in the treatment of hypogonadal men who wish to preserve endogenous testosterone production, however symptomatic responses are often suboptimal. Exogenous testosterone replacement, while effective...

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TRT Hormone Predictor Widget

Understanding Your Hormones

Estradiol (E2)

A form of estrogen produced from testosterone. Important for bone health, mood, and libido. Too high can cause side effects; too low can affect well-being.

DHT

Dihydrotestosterone is a potent androgen derived from testosterone. Affects hair growth, prostate health, and masculinization effects.

Free Testosterone

The biologically active form of testosterone not bound to proteins. Directly available for cellular uptake and biological effects.

Scientific Reference

Lakshman KM, Kaplan B, Travison TG, Basaria S, Knapp PE, Singh AB, LaValley MP, Mazer NA, Bhasin S. The effects of injected testosterone dose and age on the conversion of testosterone to estradiol and dihydrotestosterone in young and older men. J Clin Endocrinol Metab. 2010 Aug;95(8):3955-64.

DOI: 10.1210/jc.2010-0102 | PMID: 20534765 | PMCID: PMC2913038