Testosterone side effects

Optimizing Gynecomastia Correction Surgery
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Abstract Background Tumescent local anesthesia (TLA) involves infusing a saline solution containing lidocaine and epinephrine into tissues to achieve localized anesthesia and vasoconstriction. While liposuction under general anesthesia remains...
Heavier Men May Require Higher TRT Doses
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We finally have a study that looked at this common question. Effect of Weight on Serum Testosterone Levels with Subcutaneous Testosterone Enanthate in Men with Testosterone Deficiency Introduction Obesity is a common issue among men and is...
Responses of different doses of testosterone injections on body composition, strength, etc.
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Comment: 125 mg per week was the lowest dose that provided statistically significant changes in lean body mass and fat mass. PAPER ATTACHED Testosterone dose-response relationships in healthy young men. Bhasin S, et al. Am J Physiol...

Why is 200 mg/wk the "upper limit" for TRT?

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I keep seeing people post that 200 mg/wk of test propionate is the upper range for TRT and that anything more than that constitutes AAS levels, with the implication that if you go higher you are abusing the protocol. Why is that, exactly? I'm a...
Newer formulations of oral testosterone: development and liver side effects
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Abstract Introduction Testosterone deficiency is a clinical disorder due to either failure of the testes to produce testosterone or failure of the hypothalamus or pituitary to produce sufficient gonadotropins. Previous formulations of oral...
Testosterone Therapy Today: Clinical Advances & Safety with Dr. Abraham Morgentaler
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Dr. Morgentaler back in action! Listen closely, loved this one! Pros/Cons oral TU (51:24-57:12) *one of the things that the orals have transformed is the concept that you have to have a continually high level of testosterone to get...
Fertility after exogenous T replacement
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https://www.urologytimes.com/view/expert-forum-fertility-after-exogenous-testosterone-replacement In this expert panel video, Kelli Gross, MD; Kevin J. Campbell, MD, MS; Darshan P. Patel, MD; Mary K. Samplaski, MD; and James M. Hotaling, MD...
Testosterone Therapy and Erythrocytosis - the most common dose-limiting effect of testosterone therapy
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https://www.thebloodproject.com/cases-archive/testosterone-therapy-and-erythrocytosis-2/ Introduction Androgens play a crucial role in the development and maintenance of: Male reproductive and sexual functions Body composition...

TRT IN MEN WITH HYPOGONADISM AND T2DM - ABCD WORLDWIDE AUDIT

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Background Male Hypogonadism is common in Type 2 Diabetes with a prevalence of 40% having symptoms of testosterone deficiency [1]. Testosterone deficiency is associated with reduced Quality of Life (QOL), sexual, physical and psychological...
HCG Use in Men on TRT or as Monotherapy: Over 200 Questions and Answers
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I collected questions and answers posted on ExcelMale.com in the last 10 years about the use of human chorionic gonadotropin in men who want to prevent loss of testicular size and fertility while on testosterone replacement therapy or that want...

Acne on TRT, accutane cause erectile dysfunction

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How to reverse ED from accutane? I've been on a low dose of 20mg but still get ED, higher test didn't help, propionate, enanthate didn't make a difference, HCG helped very minimally. What else can I try?
IM versus Sub-q T Injections: Effect on TT, hematocrit, E2, and PSA
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Comparison of Outcomes for Hypogonadal Men Treated with Intramuscular Testosterone Cypionate Versus Subcutaneous Testosterone Enanthate (2020) Introduction Intramuscular testosterone cypionate (IM-TC) is the conventional treatment option for...
TRT Hormone Predictor Widget

TRT Hormone Predictor

Predict estradiol, DHT, and free testosterone levels based on total testosterone

⚠️ Medical Disclaimer

This tool provides predictions based on statistical models and should NOT replace professional medical advice. Always consult with your healthcare provider before making any changes to your TRT protocol.

ℹ️ Input Parameters

Normal range: 300-1000 ng/dL

Predicted Hormone Levels

Enter your total testosterone value to see predictions

Results will appear here after calculation

Understanding Your Hormones

Estradiol (E2)

A form of estrogen produced from testosterone. Important for bone health, mood, and libido. Too high can cause side effects; too low can affect well-being.

DHT

Dihydrotestosterone is a potent androgen derived from testosterone. Affects hair growth, prostate health, and masculinization effects.

Free Testosterone

The biologically active form of testosterone not bound to proteins. Directly available for cellular uptake and biological effects.

Scientific Reference

Lakshman KM, Kaplan B, Travison TG, Basaria S, Knapp PE, Singh AB, LaValley MP, Mazer NA, Bhasin S. The effects of injected testosterone dose and age on the conversion of testosterone to estradiol and dihydrotestosterone in young and older men. J Clin Endocrinol Metab. 2010 Aug;95(8):3955-64.

DOI: 10.1210/jc.2010-0102 | PMID: 20534765 | PMCID: PMC2913038

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