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ARBs like Losartan Decrease Dementia Risk
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The Angiotensin Tiebreaker: Choosing the Blood Pressure Med That Defends Your Brain 1. The Hook: More Than Just a Number Hypertension is often called the "silent killer," a leading modifiable risk factor for dementia that currently affects nearly...
Palmitoylethanolamide (PEA) to Improve Pain and Cognitive Function: A Comprehensive Review
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Palmitoylethanolamide (PEA) A Comprehensive Review of Mechanisms, Clinical Evidence, and Practical Applications January 2026 Abstract Palmitoylethanolamide (PEA) is an endogenous fatty acid amide belonging to the N-acylethanolamine family with...
Estrogen-It's what makes a real man
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Study: Low estrogen can cause problems for men Study: Low estrogen can cause problems for men (2013) Dr. Joel Finkelstein, an endocrinologist at Harvard Medical School and the lead author of a new study, talks about the effects of declining...
HUBERMAN'S, ATTIA'S, FERRIS, AND OTHER INFUENCER'S COGNITIVE & MOOD SUPPLEMENT PROTOCOLS
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This category is perhaps the most nuanced in the supplement landscape, as approaches vary significantly depending on whether the focus is acute performance enhancement, chronic mood support, or long-term neuroprotection. The following review...
Repatha (Evolocumab) Effects on Coronary Artery Calcium (CAC) Scoring and CCTA
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Prepared: January 2026, Curated by Nelson Vergel Key Finding: Evolocumab induces significant coronary plaque regression and stabilization but does not differentially affect coronary calcium accumulation compared to statin monotherapy. However...
ExcelMale.com: The Most Comprehensive TRT Forum for Men’s Health
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ExcelMale.com is widely regarded as the ultimate online forum for testosterone replacement therapy (TRT) and men’s health discussions. Founded in 2013 by a leading men’s health advocate, this platform has grown into a vast community with tens of...
Testosterone’s Schedule III Status The Evolving U.S. Regulatory Landscape
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All those so called gurus polluting social media and the half-wits pushing that more T is better mentality bull*** stinkin up those so called men's health/HRT forums! * At the same time, the non-medical environment has evolved, with online...
Protect Your Access to Compounding Products- Submit Your Testimonial
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Dear ExcelMale Members, I'm reaching out to you today with a request that's deeply personal to me and I believe to many of you as well. As some of you know, compounded medications literally saved my life. In the early days of the AIDS crisis...
Metformin Decreases Muscle Gain and Strength in Seniors
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Executive Summary The Metformin to Augment Strength Training Effective Response in Seniors (MASTERS) trial was a randomized, double-blind, placebo-controlled multicenter study designed to determine if metformin could enhance the muscle-building...
The Next Generation of Weight-Loss Medications
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When GLP-1 therapies hit the mainstream, testosterone health changed too. Now three new medications in FDA review could reshape the landscape again–not just for weight loss, but for how metabolic dysfunction relates to hormone balance in men...
Anastrozole for Men: The Complete Evidence-Based Guide for Testosterone Therapy
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By Nelson Vergel | ExcelMale.com | Updated December 2025 Introduction Should you take an aromatase inhibitor with testosterone replacement therapy? This question has sparked considerable debate in men's health circles, with some clinics routinely...
Sexual Function on TRT: Why Testosterone Alone May Not Be Enough for Erectile Function
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Many men begin testosterone replacement therapy expecting their sexual function to improve across the board—better libido, stronger erections, enhanced satisfaction. And while TRT often delivers significant benefits for desire and overall sexual...
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