Would like to know why some men choose more frequent injections at smaller does like twice weekly or E3D. Thinking of going to twice weekly

DDD

Member
Greetings all.

I am on a once weekly injection schedule with 150mg of T cyp on Mondays, then .25mg anastrozole on Tuesdays, and .1mg anastrozole on Fridays and Sundays. This causes my T to range from approx 1200 at peak and 500 seven days later before next injection. Is this a normal swing?

I'm thinking of going back to twice weekly regimen. I hear a number men say that more frequent injections of smaller doses is better for them. Why is that?

On once weekly, I usually feel a libido spike the day of injection or the next day. I take 150 mg (.75cc) on the once weekly shot. I then take .25mg of anastrozole the day after injection, but sometimes I sense the anastrozole decreases the libido spike. Would the libido be more consistent on a twice weekly or more frequent schedule?

The other question is--- how do you switch from a once weekly to twice weekly? For example, I take my once a week injection on Mondays. If I switch to twice weekly, do I start the smaller dosage on Thursday (3 days after my Monday weekly injection), or do I wait a whole week and start the twice weekly on a Monday, which would be 7 days later?

On twice weekly I'd probably do a Mon/Thur schedule with T cyp of 70-75 mg each injection and .1 mg anastrozole the day after injection.

Lastly, what are some reasons guys would choose to do an E3D or EOD regiment?

Thank you for your thoughts.
 

hCG Mixing Calculator

HCG Mixing Protocol Calculator

TRT Hormone Predictor Widget

TRT Hormone Predictor

Predict estradiol, DHT, and free testosterone levels based on total testosterone

⚠️ Medical Disclaimer

This tool provides predictions based on statistical models and should NOT replace professional medical advice. Always consult with your healthcare provider before making any changes to your TRT protocol.

ℹ️ Input Parameters

Normal range: 300-1000 ng/dL

Predicted Hormone Levels

Enter your total testosterone value to see predictions

Results will appear here after calculation

Understanding Your Hormones

Estradiol (E2)

A form of estrogen produced from testosterone. Important for bone health, mood, and libido. Too high can cause side effects; too low can affect well-being.

DHT

Dihydrotestosterone is a potent androgen derived from testosterone. Affects hair growth, prostate health, and masculinization effects.

Free Testosterone

The biologically active form of testosterone not bound to proteins. Directly available for cellular uptake and biological effects.

Scientific Reference

Lakshman KM, Kaplan B, Travison TG, Basaria S, Knapp PE, Singh AB, LaValley MP, Mazer NA, Bhasin S. The effects of injected testosterone dose and age on the conversion of testosterone to estradiol and dihydrotestosterone in young and older men. J Clin Endocrinol Metab. 2010 Aug;95(8):3955-64.

DOI: 10.1210/jc.2010-0102 | PMID: 20534765 | PMCID: PMC2913038

Beyond Testosterone Podcast

Online statistics

Members online
3
Guests online
130
Total visitors
133

Latest posts

Back
Top