Why the Mood Stinks 5 out of 7 days?

Dude, moodiness and swelling (water retention) are classic signs of high estrogen. Libido being out of whack is also the result of either low or high estrogen.

A very standard dosage is 100mg per week. If you want, break it up into two injections, but it's obvious your first protocol sucked, so I'd keep it simple and just do 1 shot per week until you get the dose dialed in.

A lot of guys on this forum (much respect to them!) advocate 2, or 3, or 5, small injections per week to combat various issues, but they are ADVANCED and EXPERIENCED users. Us noobs would do well to keep it simple.

Again, from my perspective, I say shoot once per week until you know what you're doing and your body adjusts.
 
Dude, moodiness and swelling (water retention) are classic signs of high estrogen. Libido being out of whack is also the result of either low or high estrogen.

A very standard dosage is 100mg per week. If you want, break it up into two injections, but it's obvious your first protocol sucked, so I'd keep it simple and just do 1 shot per week until you get the dose dialed in.

A lot of guys on this forum (much respect to them!) advocate 2, or 3, or 5, small injections per week to combat various issues, but they are ADVANCED and EXPERIENCED users. Us noobs would do well to keep it simple.

Again, from my perspective, I say shoot once per week until you know what you're doing and your body adjusts.


Keeping it simple is always the best approach. Keep in mind posters are more likely to be guys looking for help because their protocol is off, not guys with no problems and their results dialed in. Good advice on 100 once per week to figure it out.
 

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TRT Hormone Predictor Widget

TRT Hormone Predictor

Predict estradiol, DHT, and free testosterone levels based on total testosterone

⚠️ Medical Disclaimer

This tool provides predictions based on statistical models and should NOT replace professional medical advice. Always consult with your healthcare provider before making any changes to your TRT protocol.

ℹ️ Input Parameters

Normal range: 300-1000 ng/dL

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Understanding Your Hormones

Estradiol (E2)

A form of estrogen produced from testosterone. Important for bone health, mood, and libido. Too high can cause side effects; too low can affect well-being.

DHT

Dihydrotestosterone is a potent androgen derived from testosterone. Affects hair growth, prostate health, and masculinization effects.

Free Testosterone

The biologically active form of testosterone not bound to proteins. Directly available for cellular uptake and biological effects.

Scientific Reference

Lakshman KM, Kaplan B, Travison TG, Basaria S, Knapp PE, Singh AB, LaValley MP, Mazer NA, Bhasin S. The effects of injected testosterone dose and age on the conversion of testosterone to estradiol and dihydrotestosterone in young and older men. J Clin Endocrinol Metab. 2010 Aug;95(8):3955-64.

DOI: 10.1210/jc.2010-0102 | PMID: 20534765 | PMCID: PMC2913038

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