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I agree, but I have one nit to pick which I think is important. The body has a very well-developed set of mechanisms for dealing with damage to the endothelium (what we would call CVD) which suggests it expects to have to deal with that issue. Supposedly non-industrialized cultures show some degree of CVD, HOWEVER, what we really care about are heart attacks and strokes, and while CVD raises their risk somewhat, they are what has really taken off in the 20th century among industrialized people. Some of that was due to leaded gasoline fumes being an issue for a while, but all the usual suspects are likely the issue. As Dr. Kendrick says, the body is always dealing with a low level of CVD and as long as repair is comfortably greater than damage, then things are good, but when the insult overwhelms repair capacity, and/or repair capacity gets out of control due to blood clotting issues, that is where the real risk comes in. Dysregulated Zeta Potential is also a likely issue for heart attacks and strokes.
Very interesting info. There’s other parts of our bodies that are constantly breaking down and rebuilding, so what ur talking about here doesn’t sound too far fetched

Just doesn’t make sense tho that the body would evolve to always have some type of endothelium damage. Makes me think that it’s just a result of modern day living, even in remote/ non-industrialized communities. I have a hard time believing that if people were hunting heard animals, and only consuming ruminant animals, nose to tail, that had been grazing on grass, like our ancestors did for most of our evolution, that they would experience any type of CVD.
 
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Very interesting info. There’s other parts of our bodies that are constantly breaking down and rebuilding, so what ur talking about here doesn’t sound too far fetched

Just doesn’t make sense tho that the body would evolve to always have some type of endothelium damage. Makes me think that it’s just a result of modern day living, even in remote/ non-industrialized communities. I have a hard time believing that if people were hunting heard animals, and only consuming ruminant animals, nose to tail, that had been grazing on grass, like our ancestors did for most of our evolution, that they would experience any type of CVD.
I am part-way thru Dr kendrick's book-length discussion on the topic so hopefully there will be an answer in it, but I suspect it is because there are a lot of non-diet insults (like stress) that can damage the endothelium, and also because of certain areas where the blood flow is especially turbulent, which is apparently part of the reason that CVD only happens in arteries and mostly in specific points in the arteries.
 
I am part-way thru Dr kendrick's book-length discussion on the topic so hopefully there will be an answer in it, but I suspect it is because there are a lot of non-diet insults (like stress) that can damage the endothelium, and also because of certain areas where the blood flow is especially turbulent, which is apparently part of the reason that CVD only happens in arteries and mostly in specific points in the arteries.
Again, very interesting info/ concepts. I’m definitely open minded to the idea/ theory about there always being some level of endothelium damage, in some people, even when processed foods aren’t part of their diet. Very interested to hopefully hear what the reason(s) could be for it. Thanks again for sharing all this
 
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@Guided_by_Voices just finished watching a vid of Dave Asprey interviewing Dr Cate Shanahan, and wow, she’s an absolute wealth of knowledge. I already knew how bad seed oils were, but it was nice getting to hear someone talk about why they’re so bad, in such depth. And she’s also up on current research about healthy vs unhealthy fats, in general, so just all the info she had to share was great. Thanks again for mentioning her. Will definitely be watching more of her stuff
 
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