Water Retention Caused by Anabolics and Testosterone

[Nelson Vergel]

I think Patrick Arnold makes a great point about a potential mechanism for edema that has nothing to do with elevated estradiol.

People familiar with the use of anabolic steroids know that water retention and hypertension (high blood pressure) are potential side effects. This is due to the fact that all androgenic hormones have the capacity to cause some sodium retention (and hence water retention) through direct action via androgen receptors in the kidneys. Furthermore, anabolic steroids that are estrogenic or can convert to estrogens can cause even more sodium retention via additional interaction with renal (kidney) estrogen receptors. So it's often thought that an anabolic steroids propensity for water retention is related to its potency both as an androgen and as an estrogen (manifested via aromatization to estrogenic metabolites).

Confusion has often arisen however when people have noticed that some steroids – which traditional thinking tells us should not result in extraordinary water retention – end up doing just that. Steroids that should not aromatize to estrogens such as oxymetholone (anadrol) and methyl-1-testosterone are known to result in extreme water retention in some individuals. A recent paper* suggests a heretofore unmentioned explanation for this.

http://patrickarnoldblog.com/hypertension-and-anabolic-steroids-a-new-pathway/

 

[Nelson Vergel]

Ankle swelling after starting testosterone injections


Anastrozole vs water retention


Preventing Water Retention (Face & Chest)

 

[GEORGE TOULIATOS]

Oxymetholone is a DHT derivative and it shouldnt aromatise.However,it is speculated to cause an increase in beta estradiol.Other anabolics such as nandrolone,or methandrostenolone do aromatise and cause water retention too.
Water retention is the key mechanism of how steroids act on sarcoplasm.Electrolytes and minerals as calcium and sodium are responsible for edema formation.Calcification is the result of calcium storage withing arterial endothelium,or ureters.Nandrolone decaonate is prescribed for the clinical symptom of osteopenia,that leads to osteoporosis and fractures.Bone mineral densty is increased by androgens and estrogens,and nandrolone is the ideal AAS for calcium storage and osteoblastic activity.As PA mentioned,systemic hypertension is the result of water and sodium retention.Fluoxymesterone is a testosterone's derivative that it is not aromatised,however it could lead to hypertension.


http://patrickarnoldblog.com/hypertension-and-anabolic-steroids-a-new-pathway/

 

[Nelson Vergel]

Testosterone Side Effect Management Table

 

[Nelson Vergel]

TEST CYP vs TEST E & BLOATING

Water Retention from HCG

Water Retention Caused by Anabolics and Testosterone

Preventing Water Retention (Face & Chest)

Testosterone induced water retention: Guide to Natural Diuretics

TRT water retention now showing in feet

Anastrozole vs water retention

Water Retention from HCG - Page 2

Water retention

 

[GEORGE TOULIATOS]

hi George, do you believe the type of hypertension created from water retention can be Isolated hypertension?

AAS induce the release of aldosterone from kidneys.This hormone (blocked by spironolactone),is able to hold sodium,leading to edema.In cardiology,sodium is among the reasons of systemic hypertension.However,that water retention in muscle cells,is a foundamental way of muscle volumizing and strenght (anabolic enviroment-resembling creatine).