TRT + masteron microdosing for e2 control

[t_spacemonkey]

Could low-dose masteron be a better alternative to traditional AI medications for controlling estrogen on TRT? This experimental thread documents one user's attempt to manage elevated estradiol levels by adding 10 mg daily of masteron propionate to his testosterone protocol, inspired by protocols discussed in bodybuilding circles and anecdotal reports from performance-enhancing drug communities. The original poster reports initial improvements in mood and libido but ultimately abandoned the approach after experiencing significant anxiety, edginess, and what appeared to be crashed estradiol levels even at this low dose. Other members share similar experiences with DHT derivatives like masteron and proviron, noting that while these compounds can provide powerful anti-estrogenic effects and enhance masculinization, they often come with a steep downside including negative impacts on cholesterol profiles and unpredictable psychological effects. The thread reveals that masteron's ability to lower SHBG and potentially interfere with estrogen receptor activity makes dosing extremely difficult, with even small amounts producing dramatic hormonal shifts that many men find intolerable. Discover why most experienced users recommend simple dose reduction of testosterone or traditional AI use over the complexity and risks of adding DHT-derivative compounds.

so I been doing this for couple days now. my typical Tprop dosing (lowered to currently 20mg/day) + 10mg Masteron propionate. I will give it couple weeks and do blood work +e2 sensitive.
initial effects on mood/libido are very good. my e2 tends to run on the high side, 50-60 pg/ml.
according to the anabolic doc in the vid this can be done 'safely' on an ongoing basis. I might even lower the Mast to 5mg/day
and no you can't get this 'legally' in the usa, but in most of the world no problem
I wonder if anyone else tried it?

 

[Seagal]

Proviron had positive effects for me.
If high E2 is the key factor -androgen estrogen balance- I would prefer low dose exemestane (aromasin) purely for TRT.

 

[t_spacemonkey]

I abandoned this. the masteron was messing with my mood big time. not sure if due to too low e2 since I just did some tests and waiting, but my suspicion is that DHT derivates compete for receptors but don't cause the same effects. started getting really edgy+anxious. took me about a week to recover once stopped, but i reverted to baseline.

 

[Jerajera]

Had a similar experience with Mast; was also adding 10mg/day to I think 15mg/day Test P at the time; also tried with Test E. Initially great for mood and insane for libido but eventually started not feeling very good.

Also trashed my lipids pretty badly and I have a great baseline for cholesterol. Primo was even worse on lipids; 10mg/day dropped my HDL from 65 (83 pre-TRT) to ~40 at just 10mg/day, and it was HPLC blind tested Primo so 100% the real deal. Same with the Mast.

 

[Seagal]

I guess one has to find the right mix of both. I thought adding DHT might have the same effect, the positives and also the negatives on lipid and maybe agitation or anxiety for some.

 

[t_spacemonkey]

so this is 1 week after I stopped masteron. i typically run 50pg/ml. this stuff crashed my e2. maybe there is a low dose like 5mg or so but since I don't have any high e2 sides, this is pointless. too low e2 much worse then too high e2

 

[Jerajera]

View attachment 49406so this is 1 week after I stopped masteron. i typically run 50pg/ml. this stuff crashed my e2. maybe there is a low dose like 5mg or so but since I don't have any high e2 sides, this is pointless. too low e2 much worse then too high e2

I think that doesn't necessarily mean Mast lowered E2 systemtically directly. Mast lowers SHBG which in turn lowers total levels of hormones, which includes E2 (since this isn't Free E2 you tested).

For example if your SHBG drops by 20 points, your Total T will be lower than with higher SHBG with the same Free T levels.

So I don't think we can conclude that Mast lowers E2 systemically; it's very possible the discrepancy in total hormone levels is due only to lower SHBG.

 

[Jerajera]

I guess one has to find the right mix of both. I thought adding DHT might have the same effect, the positives and also the negatives on lipid and maybe agitation or anxiety for some.

I haven't seen any negative impact of extremly high (500ng/dL on a range of 12-65ng/dL) DHT levels on lipids when on scrotal cream, but definitely some overstimulation (different from anxiety for me) initially.

 

[Seagal]

Yes, from what people reported here, DHT seems to be unique.

 

[t_spacemonkey]

I think that doesn't necessarily mean Mast lowered E2 systemtically directly. Mast lowers SHBG which in turn lowers total levels of hormones, which includes E2 (since this isn't Free E2 you tested).

For example if your SHBG drops by 20 points, your Total T will be lower than with higher SHBG with the same Free T levels.

So I don't think we can conclude that Mast lowers E2 systemically; it's very possible the discrepancy in total hormone levels is due only to lower SHBG.

my shbg is below 10, not sure it can go lower, even if - it would depress e2 that much. to be fair i played with higher doses of mast 1:1 to Test, and maybe thats when I started to have issues. but this felt different when I did proviron or anavar which made me instantly edgy. this build up over time, not day, fairly certain this was due to e2

 

[ziegen]

When I was on Test E 125mg/week I tried Masteron and Proviron to "increase" DHT, since it was the only thing wrong on my blood test. Now obviously it doesn't increase it directly it just binds to receptors and the body recognizes it as DHT.

First I tried Masteron E at 50mg/week, injected 2x the same time as Test E. After 1 month I felt nothing, no positives or negatives, so I increased the dose to 100mg/week. After 3 weeks I started feeling mentally off; worse mood for no reason and the mental/logical interest in women was completely gone. There were no other changes than this. I did a blood test during this time and noticed that SHBG was exactly the same as before, yet my E2 was significantly lower. I think DHT derivatives work directly on E2 rather than indirectly via SHBG as @Jerajera noted, but that is purely my speculation based on my blood test results. In any case, after having the negative effects for a few days, I stopped taking Masteron E and 1 week later it all cleared.

Next I also tried Proviron, as many people noted that it's "even more sexual" than Masteron or other DHT derivatives. During this time I was on HCG, but I don't aromatize that much, so my T:E2 ratio was about the same, just levels were very slightly higher. I was thinking that maybe E2 from HCG would prevent an E2 crash, as I didn't have sensitive E2 tests available and it might be higher, than what's written on the blood test results. I tried 25mg/day, which is the standard dose, and again, after 3 weeks I started feeling off the same way as with Masteron. I stopped taking it and after a week I was again back to normal.

In my opinion DHT derivatives are completely unneccesary on TRT. If you want to bump DHT, then get a DHT or T cream and increase it directly. There is also the added benefit of being able to track your actual levels. If you want to decrease E2, then you can try out supplements like Calcium D Glucarate and/or DIM, which should be effective if you're trying to decrease E2 by a lesser degree. Otherwise use AIs, I think that 0.125-0.25mg per week of Arimidex should be more than enough to reduce E2 to some managable level. You can also pick Aromasin if you prefer it and take a small dose. I don't think that AIs on such small doses should present major long term risks, I don't think that DHT derivatives are any safer than AIs.

 

[WhiteMale]

23pg/ml is not low nor is it crashed...how did you even come up with that?

 

[t_spacemonkey]

23pg/ml is not low nor is it crashed...how did you even come up with that?

this was a week after stopping. i would assume it went back up significantly since I used MProp which has a short half life.

 

[t_spacemonkey]

When I was on Test E 125mg/week I tried Masteron and Proviron to "increase" DHT, since it was the only thing wrong on my blood test. Now obviously it doesn't increase it directly it just binds to receptors and the body recognizes it as DHT.

First I tried Masteron E at 50mg/week, injected 2x the same time as Test E. After 1 month I felt nothing, no positives or negatives, so I increased the dose to 100mg/week. After 3 weeks I started feeling mentally off; worse mood for no reason and the mental/logical interest in women was completely gone. There were no other changes than this. I did a blood test during this time and noticed that SHBG was exactly the same as before, yet my E2 was significantly lower. I think DHT derivatives work directly on E2 rather than indirectly via SHBG as @Jerajera noted, but that is purely my speculation based on my blood test results. In any case, after having the negative effects for a few days, I stopped taking Masteron E and 1 week later it all cleared.

Next I also tried Proviron, as many people noted that it's "even more sexual" than Masteron or other DHT derivatives. During this time I was on HCG, but I don't aromatize that much, so my T:E2 ratio was about the same, just levels were very slightly higher. I was thinking that maybe E2 from HCG would prevent an E2 crash, as I didn't have sensitive E2 tests available and it might be higher, than what's written on the blood test results. I tried 25mg/day, which is the standard dose, and again, after 3 weeks I started feeling off the same way as with Masteron. I stopped taking it and after a week I was again back to normal.

In my opinion DHT derivatives are completely unneccesary on TRT. If you want to bump DHT, then get a DHT or T cream and increase it directly. There is also the added benefit of being able to track your actual levels. If you want to decrease E2, then you can try out supplements like Calcium D Glucarate and/or DIM, which should be effective if you're trying to decrease E2 by a lesser degree. Otherwise use AIs, I think that 0.125-0.25mg per week of Arimidex should be more than enough to reduce E2 to some managable level. You can also pick Aromasin if you prefer it and take a small dose. I don't think that AIs on such small doses should present major long term risks, I don't think that DHT derivatives are any safer than AIs.

interesting. yeah having very similar exp with Proviron. it nuked me much quicker then you. I found that in addition to T injection, low dose Tcream on scrotum raises my libido significantly I assume due to DHT boost. and I also need to avoid all DHT derivatives from now on.