TRT and Cortisol

[Btoledo85]

These are my labs done at 530pm. Normal cortisol at that time ranges from 3-10. Mine was 2.9. Ran a MRI for Pituary Tumor came up with none present . Now Endo wants to run a cortisol stimulation test to rule out adrenal insufficiency before puts me on TRT. Could this just be cuz the time of day it was drawn and should I still start TRT?

 

[Systemlord]

TRT lowers cortisol, not good if you have an adrenal insufficiency. Secondary hypogonadism can present with low testosterone and low cortisol.

HCG which mimics the pituitary hormone LH, which increases testosterone and increases cortisol as well as other hormones.

You likely don’t have an adrenal problem, but rather a pituitary signaling hormone insufficiency.

I wouldn’t expect your Endo to be very helpful helping you dialing in on TRT, as Endo’s the majority of their time are clueless dishing out protocols that result in treatment failure.

So you’ll need to be your own advocate. Avoid protocols with injections every two weeks, at a minimum you want to be injecting 80-100 mg once a week wait a minimum of six weeks for lab testing. Twice a week is common, so 40 mg twice weekly.

 

[Btoledo85]

Appreciate the reply. I’m actually doing the cream . And I believe it’s 140 twice a day . I was told if I go lower than 140 that it can do more harm than good and crash my testosterone. I’m just a little apprehensive as I’ve never been on any kind of testosterone or hCG. I also bought naringin and nattokinase just in case my blood pressure rises, which I’ve never had, and to lower my RBC and Hemo. He also advised me to distribute the cream under the scrotum area.