madman
Super Moderator
Testosterone Therapy in High-Risk Men for Prostate Cancer
A video from Edoardo Pozzi, posted on Mar 25, 2025.
Poor metabolic health is a major risk factor for prostate cancer, which results in high levels of insulin (one of the most potent growth factors for cancer), inflammation, etc.
TRT is not. Men with active prostate cancer are even being treated with TRT now without any adverse effects on progression or mortality:
Oncologic Outcomes of Testosterone Therapy for Men on Active Surveillance for Prostate Cancer: A Population-based Analysis - PMC
In this population-based study, testosterone therapy for men on active surveillance for prostate cancer did not worsen mortality. Keywords: Testosterone, Prostate cancer, Outcomes, Active surveillancepmc.ncbi.nlm.nih.gov
Look into the saturation model of androgens in the prostate. It takes a very low level of serum testosterone (like serious hypogonadism) to produce intraprostate levels...
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