T in Prostate Cancer, in Combination with GH Secretagogues, and in Fertility - Dr. Lipshultz

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15:47-17:57 (T levels on therapy/sides)

* The right answer is you've got to keep testosterone within the normal range which is 200/300-1000 ng/dL but its very hard to do and make the patient feel well, they will feel better in the higher-end of that regimen rather than the lower-end





In this episode, Dr. Amy Pearlman interviews Dr. Larry lipshultz, one of the most prolific and well known hormone specialists in the world. He is Professor of Urology and Chief of the Scott Department of Urology's Division of Male Reproductive Medicine and Surgery at Baylor College of Medicine. They explore the evolving and sometimes controversial landscape of testosterone therapy in men with a history of prostate cancer. They also discuss when testosterone may be safely considered in men who have been diagnosed with prostate cancer prior to prostate cancer treatment- emphasizing the importance of individualized care, discussions with all treating physicians, and close monitoring.




Drs. Pearlman and Lipshultz also dive into two hot topics in men’s hormone health:

* Growth Hormone Secretagogues – With growing interest but limited clinical data, I speak with Dr. Lipshultz about his experience using these medications alongside TRT.

*
Fertility Preservation on TRT – What role do FSH and hCG play for men hoping to maintain or restore fertility while on testosterone? We review Dr. Lipshultz's recent research and how these therapies are being used in clinical practice.




As always, patient-centered care, shared decision-making, and a nuanced understanding of the data are key.
 
post #15/16/17/18/19




 
* Fertility Preservation on TRT – What role do FSH and hCG play for men hoping to maintain or restore fertility while on testosterone? We review Dr. Lipshultz's recent research and how these therapies are being used in clinical practice.










 
 
 

hCG Mixing Calculator

HCG Mixing Protocol Calculator

TRT Hormone Predictor Widget

TRT Hormone Predictor

Predict estradiol, DHT, and free testosterone levels based on total testosterone

⚠️ Medical Disclaimer

This tool provides predictions based on statistical models and should NOT replace professional medical advice. Always consult with your healthcare provider before making any changes to your TRT protocol.

ℹ️ Input Parameters

Normal range: 300-1000 ng/dL

Predicted Hormone Levels

Enter your total testosterone value to see predictions

Results will appear here after calculation

Understanding Your Hormones

Estradiol (E2)

A form of estrogen produced from testosterone. Important for bone health, mood, and libido. Too high can cause side effects; too low can affect well-being.

DHT

Dihydrotestosterone is a potent androgen derived from testosterone. Affects hair growth, prostate health, and masculinization effects.

Free Testosterone

The biologically active form of testosterone not bound to proteins. Directly available for cellular uptake and biological effects.

Scientific Reference

Lakshman KM, Kaplan B, Travison TG, Basaria S, Knapp PE, Singh AB, LaValley MP, Mazer NA, Bhasin S. The effects of injected testosterone dose and age on the conversion of testosterone to estradiol and dihydrotestosterone in young and older men. J Clin Endocrinol Metab. 2010 Aug;95(8):3955-64.

DOI: 10.1210/jc.2010-0102 | PMID: 20534765 | PMCID: PMC2913038

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