I have recenlty started TRT with HCG for low T at age 62. My total testosterone level has been gradually dropping over the past few years:
Feb 2019 401
Feb 2024 386
May 2025 296
Sep 2025 322
Oct 2025 249
Nov 2025 334
When I saw the level of 249 I decided I should try TRT since, while fit, I have had low muscle mass, fatigue, poor sleep, and apathy. But my sexual function has been pretty much unchanged since a young age - no problems at all with erections or libido.
Started TC 50 mg SQ twice a week, beginning on Nov 7. I am also concurrently doing HCG 250 IU SQ twice a week, primarily to avoid testicular atrophy and to allow for a quicker recovery of normal testicular function should I decide to stop.
I have noticed a definite impact on my sexual function. Erections are slow and not as rock hard as before. Orgasms are OK, but lack the intensity they had a few weeks ago.
I didn't have any particular thoughts about sexual function since I didn't have any problems, but I would have thought that it would be a favorable impact if anything.
Here are my labs just prior to starting TRT/HCG:
(I started heavy resistance training in October which may have had an impact on TT)
Total Testosterone: 334 ng/dl (Oct was 249)
Free Test (equilibrium dialysis): 56.5 pg/ml (Oct was 45)
SHBG: 23 nmol/L
LH: 4.2 mIU/ml
Estradiol (ultrasensitive): 28 pg/ml (normal <29)
So I'm confused. The estradiol level was borderline high at baseline based on the labs reported normal of less than 29 (Quest), even though most authorities consider 10-40 within normal range. Also the T:E ratio of about 12 is pretty normal.
Since that was the only clue, I took .25 mg of Anastrazole to see if I notice any impact.
Has anyone else had this type of experience?
Any thoughts on cause or plan of action?
Thanks for any help
Feb 2019 401
Feb 2024 386
May 2025 296
Sep 2025 322
Oct 2025 249
Nov 2025 334
When I saw the level of 249 I decided I should try TRT since, while fit, I have had low muscle mass, fatigue, poor sleep, and apathy. But my sexual function has been pretty much unchanged since a young age - no problems at all with erections or libido.
Started TC 50 mg SQ twice a week, beginning on Nov 7. I am also concurrently doing HCG 250 IU SQ twice a week, primarily to avoid testicular atrophy and to allow for a quicker recovery of normal testicular function should I decide to stop.
I have noticed a definite impact on my sexual function. Erections are slow and not as rock hard as before. Orgasms are OK, but lack the intensity they had a few weeks ago.
I didn't have any particular thoughts about sexual function since I didn't have any problems, but I would have thought that it would be a favorable impact if anything.
Here are my labs just prior to starting TRT/HCG:
(I started heavy resistance training in October which may have had an impact on TT)
Total Testosterone: 334 ng/dl (Oct was 249)
Free Test (equilibrium dialysis): 56.5 pg/ml (Oct was 45)
SHBG: 23 nmol/L
LH: 4.2 mIU/ml
Estradiol (ultrasensitive): 28 pg/ml (normal <29)
So I'm confused. The estradiol level was borderline high at baseline based on the labs reported normal of less than 29 (Quest), even though most authorities consider 10-40 within normal range. Also the T:E ratio of about 12 is pretty normal.
Since that was the only clue, I took .25 mg of Anastrazole to see if I notice any impact.
Has anyone else had this type of experience?
Any thoughts on cause or plan of action?
Thanks for any help
