T Recovery in Patients With Prostate Cancer Treated With Radiotherapy Plus ADT

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Testosterone Recovery in Patients With Prostate Cancer Treated With Radiotherapy Plus ADT - Tanya Dorff

Tanya Dorff and Alicia Morgans discuss testosterone suppression and recovery in prostate cancer patients. They review data presented by Dr. Nabid, an analysis looking at a large set of patients treated on two different clinical trials of radiation therapy plus different durations of androgen...

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Tanya Dorff and Alicia Morgans discuss testosterone suppression and recovery in prostate cancer patients. They review data presented by Dr. Nabid, an analysis looking at a large set of patients treated on two different clinical trials of radiation therapy plus different durations of androgen deprivation. With six months of androgen deprivation therapy (ADT), 75% of men recovered normal testosterone levels, but the median time to recovery was 18 months. With 18 months of ADT, only a quarter of men recovered to normal levels, and the average time was five years. Dr. Dorff emphasizes the importance of discussing this data when talking to our patients about the side effects of ADT, how long they may last, and will they recover their testosterone, and if so, when?

 

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Persistent Testosterone Suppression After Cessation of ADT for Prostate Cancer

Persistent Testosterone Suppression After Cessation of Androgen Deprivation Therapy for Prostate Cancer (2022) Jessica Delgado, Jesse Ory, Justin Loloi, Nicholas A. Deebel, Ari Bernstein, Sirpi Nackeeran, Isaac Zucker, Ranjith Ramasamy Abstract Introduction Many men receiving temporary...

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TRT and the Prostate

Testosterone Treatment and the Risk of Prostate Adverse Events (2022) Jason A. Levy, DO, MS, Arthur L. Burnett, MD, MBA, Adrian S. Dobs, MD, MHS INTRODUCTION Definition Hypogonadism is a clinical syndrome that results from failure of the testis to produce physiologic concentrations of...

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