Apologies for the lack of details. Approximately 4+ months into TRT. Protocol change from 1/2g 200mg/g compounded cream daily (approximately 100mg/week) to 128mg T Cyp injected SubQ split E3.5D with 350 IU HCG E3.5D. Changed protocol several weeks ago.
On the road and don’t have labs accessible but total T level on cream was 795, free T above range max (I have 26 lowish SHBG) accompanied by E2 sensitive of around 39 just above range max.
Recently the scrotum tightness has become pretty uncomfortable - awkward to sit/sleep without things situated just right, etc.
Wondering if this could have been worsened by the dose increase and what I’m taking a wild guess will also be an E2 increase, or if this is a normal progression 4+ months into TRT. Sure hope it’s a somewhat controllable variable - I feel like I’m pretty much sitting on my nuts as I write this. Testicular size is ok since adding HCG, but the scrotum tightness is getting worse.