Scrotum Tightness - Dosage

S1W

Well-Known Member
Have any of you guys experienced a relationship between scrotum tightness and dose? For example, higher relative dose scrotum is tighter, lower relative dose scrotum is looser?
 
I have not noticed any difference but I have only been on two different dosages. I also have taken HCG since before starting TRT.
 
Apologies for the lack of details. Approximately 4+ months into TRT. Protocol change from 1/2g 200mg/g compounded cream daily (approximately 100mg/week) to 128mg T Cyp injected SubQ split E3.5D with 350 IU HCG E3.5D. Changed protocol several weeks ago.

On the road and don’t have labs accessible but total T level on cream was 795, free T above range max (I have 26 lowish SHBG) accompanied by E2 sensitive of around 39 just above range max.

Recently the scrotum tightness has become pretty uncomfortable - awkward to sit/sleep without things situated just right, etc.

Wondering if this could have been worsened by the dose increase and what I’m taking a wild guess will also be an E2 increase, or if this is a normal progression 4+ months into TRT. Sure hope it’s a somewhat controllable variable - I feel like I’m pretty much sitting on my nuts as I write this. Testicular size is ok since adding HCG, but the scrotum tightness is getting worse.
 
I seem to be having some trouble with scrotum tightness also. Am on 140 of test per week with 2 shots intermuscular. Just had my app with Dr. Saya but forgot to mention it. Testicle size seem to be fine.
 

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