Prostate cancer: Is BAT (Bipolar Androgen Therapy) a game changer?

madman

Super Moderator

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Summary

Prostate Cancer Lab #21 discusses the effectiveness of Bipolar Androgen Therapy (BAT) in treating metastatic prostate cancer. The speaker shares their success story with BAT and highlights its potential benefits.


Highlights

  • BAT involves alternating between high and low testosterone levels to shock prostate cancer cells.
  • The speaker experienced a significant drop in PSA levels and improvement in symptoms after undergoing BAT.
  • BAT has shown promising results in certain patient populations, such as those with AR copy number gain and p53 alterations.
  • The cost of BAT is significantly lower compared to other prostate cancer treatments.
  • Further research and data collection are needed to identify predictive markers of response and explore the use of BAT in combination with other therapies.
 


 

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Predict estradiol, DHT, and free testosterone levels based on total testosterone

⚠️ Medical Disclaimer

This tool provides predictions based on statistical models and should NOT replace professional medical advice. Always consult with your healthcare provider before making any changes to your TRT protocol.

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Understanding Your Hormones

Estradiol (E2)

A form of estrogen produced from testosterone. Important for bone health, mood, and libido. Too high can cause side effects; too low can affect well-being.

DHT

Dihydrotestosterone is a potent androgen derived from testosterone. Affects hair growth, prostate health, and masculinization effects.

Free Testosterone

The biologically active form of testosterone not bound to proteins. Directly available for cellular uptake and biological effects.

Scientific Reference

Lakshman KM, Kaplan B, Travison TG, Basaria S, Knapp PE, Singh AB, LaValley MP, Mazer NA, Bhasin S. The effects of injected testosterone dose and age on the conversion of testosterone to estradiol and dihydrotestosterone in young and older men. J Clin Endocrinol Metab. 2010 Aug;95(8):3955-64.

DOI: 10.1210/jc.2010-0102 | PMID: 20534765 | PMCID: PMC2913038

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