On TRT - HCG causing bloat/fat gain, even with normal E2 numbers?

switzoton

New Member
Has anyone else experienced this?

Originally I was taking 50 mg T e3d. My trough was around 800-850 and E2 between 24 and 26 on multiple tests. I don't use AIs.

I am now taking 250iu HCG every 3 days with a 40mg T shot. My T levels are about the same, and my E2 is consistently coming back between 28 and 31 at my trough on the sensitive test.

I always eat very clean. When I am on test only, I can easily maintain ~12% body fat and don't carry much water.

Since adding the HCG, I have noticeable mild water retention - but mainly significant fat gain around the love handles, stomach, and chest area, despite having almost exactly the same T and E2 numbers as when I was on test only. My appetite is actually lower and I am still gaining fat.

Is there any reason besides estrogen that could cause this? Is it the huge bump in progesterone?

I like to keep things simple. If I have to take some other medication to counteract the bloat/fat gain, I'd rather just not use the HCG at all.
 
The more likely answer is Estrogen, could be Prog, could be anything. There are a number of us guys on this forum that don't tolerate HCG very well, for whatever reason.
 
Has anyone else experienced this?

Originally I was taking 50 mg T e3d. My trough was around 800-850 and E2 between 24 and 26 on multiple tests. I don't use AIs.

I am now taking 250iu HCG every 3 days with a 40mg T shot. My T levels are about the same, and my E2 is consistently coming back between 28 and 31 at my trough on the sensitive test.

I always eat very clean. When I am on test only, I can easily maintain ~12% body fat and don't carry much water.

Since adding the HCG, I have noticeable mild water retention - but mainly significant fat gain around the love handles, stomach, and chest area, despite having almost exactly the same T and E2 numbers as when I was on test only. My appetite is actually lower and I am still gaining fat.

Is there any reason besides estrogen that could cause this? Is it the huge bump in progesterone?

I like to keep things simple. If I have to take some other medication to counteract the bloat/fat gain, I'd rather just not use the HCG at all.
 
I take 250 mcg 2 times a week with 75mg xyosted injection once a week and my stomach has swelled enormously. Tried Kisspeptin with the same bloating issues. Any alternatives or something I can take to counter the bloating? I appreciate any feedback or suggestions.
Thanks.
 

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⚠️ Medical Disclaimer

This tool provides predictions based on statistical models and should NOT replace professional medical advice. Always consult with your healthcare provider before making any changes to your TRT protocol.

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Understanding Your Hormones

Estradiol (E2)

A form of estrogen produced from testosterone. Important for bone health, mood, and libido. Too high can cause side effects; too low can affect well-being.

DHT

Dihydrotestosterone is a potent androgen derived from testosterone. Affects hair growth, prostate health, and masculinization effects.

Free Testosterone

The biologically active form of testosterone not bound to proteins. Directly available for cellular uptake and biological effects.

Scientific Reference

Lakshman KM, Kaplan B, Travison TG, Basaria S, Knapp PE, Singh AB, LaValley MP, Mazer NA, Bhasin S. The effects of injected testosterone dose and age on the conversion of testosterone to estradiol and dihydrotestosterone in young and older men. J Clin Endocrinol Metab. 2010 Aug;95(8):3955-64.

DOI: 10.1210/jc.2010-0102 | PMID: 20534765 | PMCID: PMC2913038

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