New Labs - Looking for Feedback

agrandy

New Member
Long time reader, first post (besides my intro). I've been on TRT cream since Thanksgiving. Two clicks in the AM. Just got my latest labs from Quest and looking for feedback.

Specific questions:
  • Total T is 434 ng/dL (MS, 250-1100 ng/dL). Free T is 68.4 pg/mL (46.0-224.0 pg/mL). The labs were taken in the morning prior to daily application, so this is my daily trough. This seems slightly low?
  • SHBG is 26 nmol/L (10-50 nmol/L). What is an optimal range for SHBG?
  • Estradiol is 57 pg/mL (Ultrasensitive LC/MS, < OR = 29 pg/mL). Quest says this is high. Curious what you think? I don't feel that I have any adverse symptoms, so maybe it is fine?
  • DHT is 208 ng/dL (LC/MS/MS, 12-65 ng/dL). I am thinking about switching to injections to minimize the 5ar conversion which, I understand, is higher with cream. Thoughts? Only concern would be driving estradiol higher with every 3.5 day injections.
  • I see my doctor Thursday. What questions should I ask?
Thanks in advance!

-Adam

Lab Results 1.jpg

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TRT Hormone Predictor

Predict estradiol, DHT, and free testosterone levels based on total testosterone

⚠️ Medical Disclaimer

This tool provides predictions based on statistical models and should NOT replace professional medical advice. Always consult with your healthcare provider before making any changes to your TRT protocol.

ℹ️ Input Parameters

Normal range: 300-1000 ng/dL

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Understanding Your Hormones

Estradiol (E2)

A form of estrogen produced from testosterone. Important for bone health, mood, and libido. Too high can cause side effects; too low can affect well-being.

DHT

Dihydrotestosterone is a potent androgen derived from testosterone. Affects hair growth, prostate health, and masculinization effects.

Free Testosterone

The biologically active form of testosterone not bound to proteins. Directly available for cellular uptake and biological effects.

Scientific Reference

Lakshman KM, Kaplan B, Travison TG, Basaria S, Knapp PE, Singh AB, LaValley MP, Mazer NA, Bhasin S. The effects of injected testosterone dose and age on the conversion of testosterone to estradiol and dihydrotestosterone in young and older men. J Clin Endocrinol Metab. 2010 Aug;95(8):3955-64.

DOI: 10.1210/jc.2010-0102 | PMID: 20534765 | PMCID: PMC2913038

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