Mood, libido

It's a solid rule of practice, followed by all doctors who understand TRT, that a change in protocol - ANY change of any sort - is like pushing the reset button. One should make one change at a time, monitor symptoms, obtain the proper labs, and only then evaluate how you feel. Change multiple things at one time, then react to a subjective response...it's a path that will lead you nowhere.

Gene Devine was correct in the second post in this thread - everyone of us is guessing here in the absence of labs.
 
So I stopped the DHEA about 4 or 5 days ago. I feel better already. Been waking up with erections, and my mood is much better too. Thank you to Vince for bringing to my attention.

I agree that only one thing should be changed at a time. So I haven't changed my dosage of T. It's been the same for months and I have always felt great until recently. I think my estrogen has been a little high and I dropped the DHEA. I'll keep on with my T dosage of 200 for a few months and see if everything stays good.
Thank you for your help.
 
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So I stopped the DHEA about 4 or 5 days ago. I feel better already. Been waking up with erections, and my mood is much better too. Thank you to Vince for bringing to my attention.

I agree that only one thing should be changed at a time. So I haven't changed my dosage of T. It's been the same for months and I have always felt great until recently. I think my Eatrigen has been a little high and I dropped the DHEA. I'll keep on with my T dosage of 200 for a few months and see if ieverything stays good.
Thank you for your help.

That's great, I hope it continues to work.
 

hCG Mixing Calculator

HCG Mixing Protocol Calculator

TRT Hormone Predictor Widget

TRT Hormone Predictor

Predict estradiol, DHT, and free testosterone levels based on total testosterone

⚠️ Medical Disclaimer

This tool provides predictions based on statistical models and should NOT replace professional medical advice. Always consult with your healthcare provider before making any changes to your TRT protocol.

ℹ️ Input Parameters

Normal range: 300-1000 ng/dL

Predicted Hormone Levels

Enter your total testosterone value to see predictions

Results will appear here after calculation

Understanding Your Hormones

Estradiol (E2)

A form of estrogen produced from testosterone. Important for bone health, mood, and libido. Too high can cause side effects; too low can affect well-being.

DHT

Dihydrotestosterone is a potent androgen derived from testosterone. Affects hair growth, prostate health, and masculinization effects.

Free Testosterone

The biologically active form of testosterone not bound to proteins. Directly available for cellular uptake and biological effects.

Scientific Reference

Lakshman KM, Kaplan B, Travison TG, Basaria S, Knapp PE, Singh AB, LaValley MP, Mazer NA, Bhasin S. The effects of injected testosterone dose and age on the conversion of testosterone to estradiol and dihydrotestosterone in young and older men. J Clin Endocrinol Metab. 2010 Aug;95(8):3955-64.

DOI: 10.1210/jc.2010-0102 | PMID: 20534765 | PMCID: PMC2913038

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