Clayboy_123
Member
if trt causes dhea to be low on labs (i.e. pre trt in the mid 100's, on trt - in the 80s), would supplementing dhea with trt, improve dhea levels and fatigue?
if trt causes dhea to be low on labs (i.e. pre trt in the mid 100's, on trt - in the 80s), would supplementing dhea with trt, improve dhea levels and fatigue?
Your dhea should increase with TRT, that's why you are told to wait on supplementing with dhea until you are tested after starting TRT. Then if levels are still low you can start supplementing with dhea.
I've been on TRT for a couple years (test only, with some anastrozole) - and just recently moved to Defy. Dr. Saya saw that my DHEA levels were very low and he prescribed 30mg DHEA + 30mg Pregnenolone daily.
Just for another data point...
May I ask what you chose...oral micronized or the cream? I had to switch up, I wasn't absorbing the cream and/or it was aromatizing as my E is/has been unexplainably high.
How long have you been using 30mg DHEA + 30mg Pregnenolone, have you had your levels checked since starting and any difference how you feel?I've been on TRT for a couple years (test only, with some anastrozole) - and just recently moved to Defy. Dr. Saya saw that my DHEA levels were very low and he prescribed 30mg DHEA + 30mg Pregnenolone daily.
Just for another data point...
How long have you been using 30mg DHEA + 30mg Pregnenolone, have you had your levels checked since starting and any difference how you feel?
Higher dose TRT and anabolics can decrease DHEA. I suggest anyone on over 150 mg per week of testosterone to get upstream hormones.
Anabolic steroids and TRT decrease SHBG, DHEA, pregnenolone and progesterone in men.
Higher dose TRT and anabolics can decrease DHEA. I suggest anyone on over 150 mg per week of testosterone to get upstream hormones.
Anabolic steroids and TRT decrease SHBG, DHEA, pregnenolone and progesterone in men.
Predict estradiol, DHT, and free testosterone levels based on total testosterone
This tool provides predictions based on statistical models and should NOT replace professional medical advice. Always consult with your healthcare provider before making any changes to your TRT protocol.
Enter your total testosterone value to see predictions
Results will appear here after calculation
A form of estrogen produced from testosterone. Important for bone health, mood, and libido. Too high can cause side effects; too low can affect well-being.
Dihydrotestosterone is a potent androgen derived from testosterone. Affects hair growth, prostate health, and masculinization effects.
The biologically active form of testosterone not bound to proteins. Directly available for cellular uptake and biological effects.
Lakshman KM, Kaplan B, Travison TG, Basaria S, Knapp PE, Singh AB, LaValley MP, Mazer NA, Bhasin S. The effects of injected testosterone dose and age on the conversion of testosterone to estradiol and dihydrotestosterone in young and older men. J Clin Endocrinol Metab. 2010 Aug;95(8):3955-64.
DOI: 10.1210/jc.2010-0102 | PMID: 20534765 | PMCID: PMC2913038