HCG VS Preg/DHEA...

jth0524

Member
I've read that HCG keeps the precursor hormones going such as Pregnenolone and DHEA. There seems to be a consensus that HCG improves the general since of well being in men on TRT. Is it possible to keep the levels of Pregnenolone and DHEA at normal levels simply by supplementation alone? Is anyone not taking HCG and supplementing with DHEA/Preg? How do you feel? I'm interested in anyone that has been in TRT for a while but has chosen not to take HCG. Can you still get the good sense of well being simply by taking DHEA/Pregnenolone supplements?
 
Those two things while they might be interconnected on down the line we typically use them for different purposes, for instance DHEA is more associated with the adrenals, than the testes. I use both HCG and daily supp DHEA/Preg. I'm not aware of one being a substitute for the other. While some hormonal production and conversion may occur in the testes and that's one reason you want to use HCG and avoid organ failure as fertility and shrunken nuts (organ failure) are just two reasons we use HCG.
 

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TRT Hormone Predictor

Predict estradiol, DHT, and free testosterone levels based on total testosterone

⚠️ Medical Disclaimer

This tool provides predictions based on statistical models and should NOT replace professional medical advice. Always consult with your healthcare provider before making any changes to your TRT protocol.

ℹ️ Input Parameters

Normal range: 300-1000 ng/dL

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Understanding Your Hormones

Estradiol (E2)

A form of estrogen produced from testosterone. Important for bone health, mood, and libido. Too high can cause side effects; too low can affect well-being.

DHT

Dihydrotestosterone is a potent androgen derived from testosterone. Affects hair growth, prostate health, and masculinization effects.

Free Testosterone

The biologically active form of testosterone not bound to proteins. Directly available for cellular uptake and biological effects.

Scientific Reference

Lakshman KM, Kaplan B, Travison TG, Basaria S, Knapp PE, Singh AB, LaValley MP, Mazer NA, Bhasin S. The effects of injected testosterone dose and age on the conversion of testosterone to estradiol and dihydrotestosterone in young and older men. J Clin Endocrinol Metab. 2010 Aug;95(8):3955-64.

DOI: 10.1210/jc.2010-0102 | PMID: 20534765 | PMCID: PMC2913038

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