Is this doctor saying the opposite about SHBG, or is there something I'm not understanding?

I agree with most of what he says, but would add that if you're going to inject daily anyway then an appropriate blend of cypionate and propionate should be on your radar. He said himself that diurnal variation is natural, whereas "taking the weekend off" is not.

He says that low-SHBG guys may not feel "stable" on daily injections. Fortunately he does not go on to claim that they would feel stable with some other injection protocol. Conventional wisdom says that low-SHBG guys have a harder-than-average time with TRT. If this is true then the reduced buffering capacity could well be a factor.
 
Jatenzo for everyone, forget about injections. Jatenzo makes TRT stupid easy from the standpoint of dialing in!

Would never fly!

No one wants to settle for average T levels.

You should know better than this, especially seeing you spend most of your time on those bro forums.

Far from common that you would find anyone running <1000 TT at the trough on once-weekly, twice-weekly (every 3.5 days), M/W/F, EOD let alone daily injections

Everyone is aiming for those sky-high FT levels 24/7.....STEADY STATE.....lol.

Could just see it now all the men on TRT.....I mean so-called HRT.....better yet OPTIMAL PRIME protocols popping those 2 soft gels daily and killing it in the gym!

LMFAO!

The sad fact of the matter is everyone is out for DEM GAINZZZ!
 

hCG Mixing Calculator

HCG Mixing Protocol Calculator

TRT Hormone Predictor Widget

TRT Hormone Predictor

Predict estradiol, DHT, and free testosterone levels based on total testosterone

⚠️ Medical Disclaimer

This tool provides predictions based on statistical models and should NOT replace professional medical advice. Always consult with your healthcare provider before making any changes to your TRT protocol.

ℹ️ Input Parameters

Normal range: 300-1000 ng/dL

Predicted Hormone Levels

Enter your total testosterone value to see predictions

Results will appear here after calculation

Understanding Your Hormones

Estradiol (E2)

A form of estrogen produced from testosterone. Important for bone health, mood, and libido. Too high can cause side effects; too low can affect well-being.

DHT

Dihydrotestosterone is a potent androgen derived from testosterone. Affects hair growth, prostate health, and masculinization effects.

Free Testosterone

The biologically active form of testosterone not bound to proteins. Directly available for cellular uptake and biological effects.

Scientific Reference

Lakshman KM, Kaplan B, Travison TG, Basaria S, Knapp PE, Singh AB, LaValley MP, Mazer NA, Bhasin S. The effects of injected testosterone dose and age on the conversion of testosterone to estradiol and dihydrotestosterone in young and older men. J Clin Endocrinol Metab. 2010 Aug;95(8):3955-64.

DOI: 10.1210/jc.2010-0102 | PMID: 20534765 | PMCID: PMC2913038

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