Injection Frequency 2xs vs 3xs

[crdbr2]

Watched a recent video by Dave Lee and he discussed how 3xs a week (MWF) injection frequency has benefits to stable levels and lessen side effects. Currently on 2xs a week 50mg x2) but if it will optimize best at 3xs, then I would like to know.

Thanks!

 

[madman]

Watched a recent video by Dave Lee and he discussed how 3xs a week (MWF) injection frequency has benefits to stable levels and lessen side effects. Currently on 2xs a week 50mg x2) but if it will optimize best at 3xs, then I would like to know.

Thanks!

Many fare well injecting twice weekly (every 3.5 days) using medium acting esterified TE/TC.

The main advantage to increasing your weekly injection frequency would be clipping the peak--->trough and blood levels will be more stable throughout the week which can help minimize sides but even then it is not just the peak/trough as the FT level achieved. steady-state can have a big impact on sides.

One can still experience sides injecting more frequently if they are still running too high a trough/steady-state FT level even when injecting daily.

Most men on TTh are injecting once or twice-weekly.

Yes there are others who inject 3x weekly, EOD or even daily.

The downfall to injecting once weekly for some is there will be a drastic difference between peak--->trough and blood levels will not be as stable throughout the week which can have a negative impact on energy, mood, libido, erectile function and recovery due to the rollercoaster effect.

Others fare well and enjoy the ride.

Splitting the weekly dose and Injecting more frequently as in every 3.5 days, 3x weekly (M/W/F), EOD or daily will clip the peak--->trough and result in. more stable blood levels throughout the week but even then it is not a given that sides will be minimized or avoided as again too many get caught up on this so called needing to achieve a high/very high FT level LOL!

Injecting daily would take the cake when it comes to clipping the peak--->.trough/stable blood levels throughout the week.

I never liked the 3X weekly protocol injecting M--48hrs--W--48hrs--F--72hrs--M (true trough)) lowest point in the week.

Would be far better off injecting EOD (every 48 hrs) if you want to clip the weekly peak--->trough and take advantage of more stable blood levels throughout the week.

Keep in mind if you decide to inject more frequently you can get away with lowering your dose slightly while still achieving a healthy trough FT.

The only way you will know what is best for you is through trial and error!

 

[RotnGun]

Many fare well injecting twice weekly (every 3.5 days) using medium acting esterified TE/TC.

The main advantage to increasing your weekly injection frequency would be clipping the peak--->trough and blood levels will be more stable throughout the week which can help minimize sides but even then it is not just the peak/trough as the FT level achieved. steady-state can have a big impact on sides.

One can still experience sides injecting more frequently if they are still running too high a trough/steady-state FT level even when injecting daily.

Most men on TTh are injecting once or twice-weekly.

Yes there are others who inject 3x weekly, EOD or even daily.

The downfall to injecting once weekly for some is there will be a drastic difference between peak--->trough and blood levels will not be as stable throughout the week which can have a negative impact on energy, mood, libido, erectile function and recovery due to the rollercoaster effect.

Others fare well and enjoy the ride.

Splitting the weekly dose and Injecting more frequently as in every 3.5 days, 3x weekly (M/W/F), EOD or daily will clip the peak--->trough and result in. more stable blood levels throughout the week but even then it is not a given that sides will be minimized or avoided as again too many get caught up on this so called needing to achieve a high/very high FT level LOL!

Injecting daily would take the cake when it comes to clipping the peak--->.trough/stable blood levels throughout the week.

I never liked the 3X weekly protocol injecting M--48hrs--W--48hrs--F--72hrs--M (true trough)) lowest point in the week.

Would be far better off injecting EOD (every 48 hrs) if you want to clip the weekly peak--->trough and take advantage of more stable blood levels throughout the week.

Keep in mind if you decide to inject more frequently you can get away with lowering your dose slightly while still achieving a healthy trough FT.

The only way you will know what is best for you is through trial and error!

What's your thoughts on a high/low peak that Test Prop promotes on daily injections?

 

[madman]

What's your thoughts on a high/low peak that Test Prop promotes on daily injections?

If you are running sensible doses being mindful of your trough FT you can take advantage of the daily peak/trough especially when it comes to sides and you can throw dopamine in there too!

Unfortunately many injecting daily TP are overmedicated.

Many are still jacked up on T 24/7 even when using TP as they are still hitting a high/very high trough.

Seen guys with lowish SHBG still hitting an absurd trough TT 1000 ng/dL with very high trough FT!

Show me a healthy young natty male walking around with a high-end peak (not trough) TT let alone 1000+ ng/dL with a high/very high FT that has low/lowish SHBG.

Such does not exist!

Post #79 sums it up!

Look over post #80 you would remember!


post #79/80

Post in thread 'Testosterone propionate supposedly the best ester?'

Aug 5, 2024

Thanks man, I'll update this thread and others of course if I see any sustained success with it.

I think I'll start with 12-15mg/day. Prop has been too stimulating for me historically and anxiety driving, but I think this might be due to E2 skyrocketing and I might be fine with the Primo in there keeping E2 down.

It might also just be that my levels vary too much and I don't do well past a certain degree of variation. According to my labs when I tested both peak and trough levels on 15mg/day Prop, my Free T levels varied by 50 or even 55%.

I think I remember @Cataceous...

• madman

• 

Post in thread 'About to Start a New Protocol'

May 25, 2025

Thanks!
My FT labs at mid-point was done by Quest and was 170.7 pg/ml (30-135) and used Dialysis. I only got the mid-point labs because I knew that my endo was going to make a decision using her Utah based lab (ARUP) for Free-T at mid-point. The ARUP lab uses Eq-Dialysis/MS but it also uses a completely different range so its not comparable with Quest or LabCorp.

My FT labs at trough used Quest's cheaper service which included:
Total T: 1102
SHBG: 74
BioAvailable: 169.3 (15-150)
Free-T (calculated): 80.6 (6-73)
Albumin: 4.6

Using the on-line calculator (and...

• madman

Post in thread 'Any Testosterone Propionate Compounding Pharmacies left?'

Today at 9:47 AM

I was using Prop Subq ED @ .13ml (I've been as high as .2ml and as low as .1ml, but .13ml was enough for me where I felt best).... I like prop precisely because of the trough (high in early day and low at night which is closest to natural test peak/low levels)... I've always struggled with sleep while on trt but for me prop is the lesser of the other 2 evils from Enan and Cyp, as I feel I get a little bit better sleep on prop.. also, I think my E is easier to control as I don't really need Adex like I do on enan/cyp and I don't carry alot of water weight. PS- I jab...

• madman

 

[Vince]

I do have a friend who in his '60s at his natural T levels are still 1000. I have another friend who is only in his 30s and his levels are only in the 400s.

 

[madman]

I do have a friend who in his '60s at his natural T levels are still 1000. I have another friend who is only in his 30s and his levels are only in the 400s.

Those natty men walking around with a high TT have high SHBG and it is far from given that they are walking around with a high FT and even then none are hitting an absurdly high FT and this is a daily short-lived peak we are talking about here!

TT means nothing without knowing where the most important fraction sits!

 

[Vince]

Those natty men walking around with a high TT have high SHBG and it is far from given that they are walking around with a high FT and even then none are hitting an absurdly high FT and this is a daily short-lived peak we are talking about here!

TT means nothing without knowing where the most important fraction sits!

I know it's only their total. That's all they had tested.