Should I try?

[Personofinterest]

Hello,

I am a 32-year-old male and I would appreciate your opinion regarding whether I might be a candidate for a TRT trial.

I have been experiencing symptoms that could be related to low testosterone such as reduced energy, lower motivation and difficulty maintaining optimal performance in the gym despite consistent training.

Relevant background:

- Age: 32
- Height: 183 cm
- Weight: ~79.5 kg
- Training: strength training ~3–4 times per week
- Medical condition: autoimmune hypothyroidism (currently treated)

Recent morning blood test results:

Total Testosterone: 5.24 ng/mL (524 ng/dL)
Free Testosterone: 10.30 pg/mL (lab range 9.1 – 32.2)
SHBG: 36.04 nmol/L
LH: 4.6 mIU/mL
FSH: 2.91 mIU/mL
Estradiol (E2): 24 pg/mL
Prolactin: 5.79 ng/mL
DHEA-S: 178 µg/dL
DHT: 338.87 pg/mL

Thyroid markers:

TSH: 2.7
Free T4: 1.24
Free T3: 2.53

IGF-1: 219 ng/mL

My total testosterone appears to be in the mid-range, but my free testosterone seems to be near the lower end of the reference range.

Given these numbers and symptoms, would a 3–6 month TRT trial be reasonable to consider?

I feel tired, exhausted, depressed.
Currently using retatrutide also.

I would really appreciate your professional opinion.

Thank you.

 

[radman]

Hello,

I am a 32-year-old male and I would appreciate your opinion regarding whether I might be a candidate for a TRT trial.

I have been experiencing symptoms that could be related to low testosterone such as reduced energy, lower motivation and difficulty maintaining optimal performance in the gym despite consistent training.

Relevant background:

- Age: 32
- Height: 183 cm
- Weight: ~79.5 kg
- Training: strength training ~3–4 times per week
- Medical condition: autoimmune hypothyroidism (currently treated)

Recent morning blood test results:

Total Testosterone: 5.24 ng/mL (524 ng/dL)
Free Testosterone: 10.30 pg/mL (lab range 9.1 – 32.2)
SHBG: 36.04 nmol/L
LH: 4.6 mIU/mL
FSH: 2.91 mIU/mL
Estradiol (E2): 24 pg/mL
Prolactin: 5.79 ng/mL
DHEA-S: 178 µg/dL
DHT: 338.87 pg/mL

Thyroid markers:

TSH: 2.7
Free T4: 1.24
Free T3: 2.53

IGF-1: 219 ng/mL

My total testosterone appears to be in the mid-range, but my free testosterone seems to be near the lower end of the reference range.

Given these numbers and symptoms, would a 3–6 month TRT trial be reasonable to consider?

I feel tired, exhausted, depressed.
Currently using retatrutide also.

I would really appreciate your professional opinion.

Thank you.

You might try to increase your protein intake and add some supplements (eg. boron, magnesium, zinc) to try to reduce your SHBG before shutting down your natural T production/HPT axis with TRT. You are too young for that. Your TT is at a decent level and Free T is normal but on the lower end. Reducing SHBG would fix that and elevate your Free T.