How do I test trough?

GerryGerrison

New Member
So on 02/16/17 I switched from test cyp 56mg e3.5 days subq, arimidex e3.5 days, to 50mg test cyp E3.5 days IM with no AI(mon morning, thursday night injections). I also switched from taking 250iu HCG on injection days to taking 250iu HCG day before injection(wed and sun). After next monday it will be 4 weeks on new protocol and doc would like me to just get total, free, and sensitive e2 done. I was planning on doing it thursday late afternoon, but if I take HCG on wednesday is that representative of a real trough? Or should I be getting blood drawn wednesday before HCG shot? I'm guessing that I would stay with the Thursday blood draw as before, but I wanted to check and see if anybody had any other opinions.

Also I had a CMP and CBC done today, and based on those results combined with the results from next week doctor will either keep dosage where it is at or adjust. Full labs including lipids will be run one month after that. So far switching to IM and lowering dose has evened my mood out significantly. I no longer feel like my estrogen is swinging from low to high like it was on a ****ing pendulum. Libido is low, but I also know I need more time on IM to really feel the difference so I am being patient. For now the increase in stable/good mood is amazing, I'm able to workout as much as I want, and I'm an overall more calm individual. Still holding out for energy level increases, and roaring libido like I used to have.
 
So on 02/16/17 I switched from test cyp 56mg e3.5 days subq, arimidex e3.5 days, to 50mg test cyp E3.5 days IM with no AI(mon morning, thursday night injections). I also switched from taking 250iu HCG on injection days to taking 250iu HCG day before injection(wed and sun). After next monday it will be 4 weeks on new protocol and doc would like me to just get total, free, and sensitive e2 done. I was planning on doing it thursday late afternoon, but if I take HCG on wednesday is that representative of a real trough? Or should I be getting blood drawn wednesday before HCG shot? I'm guessing that I would stay with the Thursday blood draw as before, but I wanted to check and see if anybody had any other opinions.

Also I had a CMP and CBC done today, and based on those results combined with the results from next week doctor will either keep dosage where it is at or adjust. Full labs including lipids will be run one month after that. So far switching to IM and lowering dose has evened my mood out significantly. I no longer feel like my estrogen is swinging from low to high like it was on a ****ing pendulum. Libido is low, but I also know I need more time on IM to really feel the difference so I am being patient. For now the increase in stable/good mood is amazing, I'm able to workout as much as I want, and I'm an overall more calm individual. Still holding out for energy level increases, and roaring libido like I used to have.

Draw just prior to a testosterone injection. Thursday, late afternoon, will be just fine.
 
So on 02/16/17 I switched from test cyp 56mg e3.5 days subq, arimidex e3.5 days, to 50mg test cyp E3.5 days IM with no AI(mon morning, thursday night injections). I also switched from taking 250iu HCG on injection days to taking 250iu HCG day before injection(wed and sun). After next monday it will be 4 weeks on new protocol and doc would like me to just get total, free, and sensitive e2 done. I was planning on doing it thursday late afternoon, but if I take HCG on wednesday is that representative of a real trough? Or should I be getting blood drawn wednesday before HCG shot? I'm guessing that I would stay with the Thursday blood draw as before, but I wanted to check and see if anybody had any other opinions.

Also I had a CMP and CBC done today, and based on those results combined with the results from next week doctor will either keep dosage where it is at or adjust. Full labs including lipids will be run one month after that. So far switching to IM and lowering dose has evened my mood out significantly. I no longer feel like my estrogen is swinging from low to high like it was on a ****ing pendulum. Libido is low, but I also know I need more time on IM to really feel the difference so I am being patient. For now the increase in stable/good mood is amazing, I'm able to workout as much as I want, and I'm an overall more calm individual. Still holding out for energy level increases, and roaring libido like I used to have.

Depending on your numbers when you have your blood drawn you may need a higher weekly dosage than 50mg twice/weekly. I still do not see why im/sub-q make that much of a difference as both methods should have the same effectiveness just absorption rates may differ.
 
Yea I agree that IM vs Sub q shouldn't have a huge difference. However I was having crazy aromatization on sub q, and had anecdotally found instances where guys felt better on IM and didn't aromatize as much. I decided to try it and drop dose from 56mg to 50mg as well so I could start low(as opposed to the 75mg I started with) and slowly titrate up based off of bloods. I started too high and have been working backwards ever since. I will post blood work after it is back and see what aromatization is like on IM. Since dose is lower I can't directly compare the two, but if I need to go higher like you hypothesized( which I probably will have to do) then I can directly compare aromatization of sub q vs IM for my personal self.
 
Personally, I like to inject both on the same day, but now I do daily T. That way I could do labs on injection day, before T and HCG, plus also fast.
 

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This tool provides predictions based on statistical models and should NOT replace professional medical advice. Always consult with your healthcare provider before making any changes to your TRT protocol.

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Understanding Your Hormones

Estradiol (E2)

A form of estrogen produced from testosterone. Important for bone health, mood, and libido. Too high can cause side effects; too low can affect well-being.

DHT

Dihydrotestosterone is a potent androgen derived from testosterone. Affects hair growth, prostate health, and masculinization effects.

Free Testosterone

The biologically active form of testosterone not bound to proteins. Directly available for cellular uptake and biological effects.

Scientific Reference

Lakshman KM, Kaplan B, Travison TG, Basaria S, Knapp PE, Singh AB, LaValley MP, Mazer NA, Bhasin S. The effects of injected testosterone dose and age on the conversion of testosterone to estradiol and dihydrotestosterone in young and older men. J Clin Endocrinol Metab. 2010 Aug;95(8):3955-64.

DOI: 10.1210/jc.2010-0102 | PMID: 20534765 | PMCID: PMC2913038

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