Have I crashed my estrogen - my doctor says no and I'm hurting

[aluminex]

I think I have crashed my estrogen. I stopped trt about 10 days ago due to bad side-effects from high testoterone and high estrogen. I also had high hematocrit.

I took some extra anastrazole (listed below) after I stopped trt to lower my estrogen. I think I overdid it. I feel like death! I have brain fog, burning skin, pressure in my head/ears, and my joints are beginning to hurt.

My doctor doesn't believe that my symptoms are from low estrogen, but clearly, my estrogen is low. He is recommending that I don't do anything and allow my system to baseline.

Based on my blood work - does it appear that low estrogen is my issue? If not, what else could it be?
It it is low estrogen and I am no longer injecting - what can I do to raise it quicker? I am concerned that since I am not producing much testosterone on my own right now - that I won't produce enough to aramotize to fix my estrogen issues.


Here is my pre-trt bloodwork.




Here is my bloodwork after 12 weeks. I have really high testosterone and estrogen. I had terrible side effects. It was recommended that I stop TRT until giving blood, but my PCP recommended I stop TRT, so I didn't start back. It's been about 10 days now.




I took some additional anastrozole .5mg and then .25mg a few days later and then .25mg on Monday. Hear is my latest blood work.

 

[mooseman109]

I can comment on hematocrit, i have never had estrogen crash. It seems weird that yours went from 55.9to 51.8 it what appears to be a short time. How long between the two lab tests that you posted?
I lived at 54-55 for a couple years not knowing it was wrong. Mine stays 51-53 now and i am thrilled

 

[aluminex]

I can comment on hematocrit, i have never had estrogen crash. It seems weird that yours went from 55.9to 51.8 it what appears to be a short time. How long between the two lab tests that you posted?
I lived at 54-55 for a couple years not knowing it was wrong. Mine stays 51-53 now and i am thrilled

8/8 for the blood draw with high hematocrit
8/20 blood draw for the lower hematrocrit

I did have a phlebotomy between the two.

 

[Vince]

I would stop taking an AI, donate blood and get the right sensitive estrogen test LC/MS/MS for men.

 

[HealthMan]

I think I have crashed my estrogen. I stopped trt about 10 days ago due to bad side-effects from high testoterone and high estrogen. I also had high hematocrit.

I took some extra anastrazole (listed below) after I stopped trt to lower my estrogen. I think I overdid it. I feel like death! I have brain fog, burning skin, pressure in my head/ears, and my joints are beginning to hurt.

My doctor doesn't believe that my symptoms are from low estrogen, but clearly, my estrogen is low. He is recommending that I don't do anything and allow my system to baseline.

Based on my blood work - does it appear that low estrogen is my issue? If not, what else could it be?
It it is low estrogen and I am no longer injecting - what can I do to raise it quicker? I am concerned that since I am not producing much testosterone on my own right now - that I won't produce enough to aramotize to fix my estrogen issues.


Here is my pre-trt bloodwork.

View attachment 5654


Here is my bloodwork after 12 weeks. I have really high testosterone and estrogen. I had terrible side effects. It was recommended that I stop TRT until giving blood, but my PCP recommended I stop TRT, so I didn't start back. It's been about 10 days now.

View attachment 5655


I took some additional anastrozole .5mg and then .25mg a few days later and then .25mg on Monday. Hear is my latest blood work.

View attachment 5656

Did you stop testosterone injections and started to randomly take anastrozole? You estradiol test is the wrong one but definitely it is very low. Just stop the anastrozole and give it sometime. You estradiol should bounce back.

 

[aluminex]

I would stop taking an AI, donate blood and get the right sensitive estrogen test LC/MS/MS for men.

Thanks - I had a small AI dose on Monday, but haven't had anything since - I'm done with it.

 

[aluminex]

Did you stop testosterone injections and started to randomly take anastrozole? You estradiol test is the wrong one but definitely it is very low.

I stopped testosterone injections and yes - took some AI to get my estrogen lower because I started developing gyno and had bad symptoms from high estrogen. I think I took too much.

 

[HealthMan]

I stopped testosterone injections and yes - took some AI to get my estrogen lower because I started developing gyno and had bad symptoms from high estrogen. I think I took too much.

Yes you did and you stopped the testosterone injections (which were the cause of the high estradiol in the first place). If you are not planning to resume testosterone injections just stop anastrozole. If gyno still an issue you can try tamoxifen.

 

[aluminex]

Yes you did. If you are not planning to resume testosterone injections just stop anastrozole.

So, should that normalize? I thought about doing another injection without AI and then stop, but wasn't sure what to do.

 

[HealthMan]

So, should that normalize? I thought about doing another injection without AI and then stop, but wasn't sure what to do.

In my opinion just stop and let your body go back to baseline.

 

[aluminex]

In my opinion just stop and let your body go back to baseline.

It's painful man... =-(

Do I have any serious health concerns to worry about or should I be okay. My anxiety is through the roof which doesn't help.

 

[HealthMan]

It's painful man... =-(

Do I have any serious health concerns to worry about or should I be okay. My anxiety is through the roof which doesn't help. I seriously need a hug lol.

You put your body through a lot of hormonal changes. Everything badly managed. So not surprised you don’t feel good. Give it sometime and things should get back to normal

 

[aluminex]

You put your body through a lot of hormonal changes. Everything badly managed. So not surprised you don’t feel good. Give it sometime and things should get back to normal

Thank you! I think my Dr started me on too high of a protocol initially. I'm sure it was typical, but everyone is different so my body responded horribly to it after a while. Then I tried to fix my estrogen myself because I didn't have confidence in the Dr. - big mistake on my end.

 

[HealthMan]

Thank you! I think my Dr started me on too high of a protocol initially. I'm sure it was typical, but everyone is different so my body responded horribly to it after a while. Then I tried to fix my estrogen myself because I didn't have confidence in the Dr. - big mistake on my end.

Lesson learnt. Find a good doctor. If you are hypogonodal a proper TRT protocol can be life changing

 

[aluminex]

Lesson learnt. Find a good doctor. If you are hypogonodal a proper TRT protocol can be life changing

I'm a little gun shy now. Maybe in the future once I get passed this.

 

[HealthMan]

I'm a little gun shy now. Maybe in the future once I get passed this.

What was your original protocol and when did you draw blood (relative to your injection day)?

 

[aluminex]

350 IU hCG day 1
350 IU hCG day 2
130 mg Cyp day 3
.5 Anastrozole day 4

Blood draw was 4-5 days after my test injection.

 

[HealthMan]

350 IU hCG day 1
350 IU hCG day 2
120 mg Cyp day 3
.5 Anastrozole day 4

Blood draw was 4-5 days after my test injection.

You would rpt that every week?

 

[aluminex]

You would rpt that every week?

Yes - sorry, it was 130mg Cyp - I corrected

 

[HealthMan]

Yes - sorry, it was 130mg Cyp - I corrected

Gotcha. Now it makes sense. Too much testosterone in one dosage creating a supraphysiological peak driving your HCT and estradiol too high. Your outcome would most likely be very different if you had split your injection 2x week on a lower dosage and adding anastrozole in a small dosage also twice a week if necessary.