Gene's Nitric Oxide Stack

Many have used this stack for massive hard pumps in the gym, significant vascularity and excellent erectile function not discounting the health benefits. If you're looking for any of these benefits and more...give it a try!

Nitric Oxide Stack
Bed Time
5 mg of Tadalafil (Cialis)
3000 mg of L-Arginine
1500 mg of L-Citrulline
50 mg of Pycnogenol
150 mg of Icariin (Horny Goat Weed)
1 mg of Doxazosin (Alpha Blocker)


Morning
3000 mg of L-Arginine
1500 mg of L-Citrulline
50 mg of Pycnogenol
150 mg of Icariin (Horny Goat Weed)


nitric oxide excelmale.webp

Afternoon
5 mg of Tadalafil (Cialis)
3000 mg of L-Arginine
1500 mg of L-Citrulline
50 mg of Pycnogenol
150 mg of Icariin (Horny Goat Weed)
1 mg of Doxazosin (Alpha Blocker)



More Than a Muscle Pump: The Surprising Science of the Nitric Oxide Stack

In the biohacking world, we often chase complex peptides or experimental compounds, but we frequently overlook the most fundamental currency of life: blood flow. In the quest for longevity, systemic vascular efficiency is the baseline upon which all other health markers are built. As we age, our ability to maintain vasodilatory capacity diminishes, impacting everything from cognitive sharpness to metabolic health. "Gene’s Nitric Oxide Stack," a protocol born and refined within the ExcelMale community, has emerged as a definitive solution for men seeking to optimize this system. This isn't just a gym supplement routine; it is a sophisticated approach to anti-aging that leverages amino acids and targeted pharmaceutical interventions to restore the body’s most vital delivery mechanism.

Beyond the Mirror: The Science of the Sustained Pump​

For the average gym-goer, the "pump" is a transient aesthetic goal—a fleeting moment of muscle fullness. However, for a longevity specialist, a "harder pump" and increased vascularity are indicators of high-functioning endothelial health. The Nitric Oxide Stack is engineered to produce a state of vasodilation that doesn't simply vanish when you rack the weights.

By optimizing the nitric oxide signaling pathway, this protocol facilitates a sustained pump that carries through your daily life. This is a critical distinction: the visual vascularity is a proxy for your body’s ability to keep its "pipes" open. When you maintain that fullness hours after a workout, you are essentially providing proof of concept that your circulatory system is operating at peak efficiency, ensuring constant nutrient delivery to peripheral tissues.

The Foundation of Performance: Hard Science for Sexual Vitality​

One of the most immediate benefits of systemic vasodilation is the restoration of sexual function. From a clinical perspective, erection quality is often the "canary in the coal mine" for cardiovascular health. Because the Nitric Oxide Stack focuses on the root physiological requirements of performance—blood flow and retention—it provides a robust alternative to temporary fixes.

A Serious Solution for Erection Quality and Duration

This stack addresses both the quality and the duration of erections with clinical precision. For men navigating the aging process, this is not a matter of vanity, but of maintaining vital physiological function. By ensuring the vascular system can respond effectively to neurological signals, the protocol allows for a level of performance that many mistakenly believe is lost to time.

The Ultimate Nootropic: Future-Proofing the Neocortex​

Perhaps the most compelling argument for nitric oxide optimization is the "bodybuilder to brain health" pipeline. While most men start this stack for its physical benefits, they are unknowingly deploying a powerful shield against age-related cognitive decline. As we age, the micro-vasculature within the brain tends to narrow and tighten, a process that starves the brain of oxygen and is a primary driver of age-related dementia.

The stack acts as a nootropic by ensuring that the brain's smallest vessels remain dilated and resilient. This ensures that the neocortex and other critical regions receive a constant supply of the nutrients required for cognitive longevity. As the source material highlights:

"by increasing nitric oxide and getting that vascular dilation we're getting oxygen blood and nutrients in the areas of the brain that can provide us with a great anti-aging benefit in terms of neurological health."

The irony is profound: a protocol often associated with the bicep curl may actually be one of your most effective tools for protecting your mind.

Systemic Management: Blood Pressure and Prostate Function​

The benefits of the stack extend into the deeper mechanics of men’s health, specifically regarding the relaxation of smooth muscle tissue. This is particularly relevant for Benign Prostate Hyperplasia (BPH) and blood pressure management. Nitric oxide serves as a signal for these tissues to relax, directly easing the "inability to ease the problems" that typically characterize age-related prostate issues.

The secondary physiological advantages of this systemic relaxation include:

  • Vascular Tension Reduction: Significant support for maintaining healthy blood pressure levels by reducing resistance within the arterial walls.
  • Prostate Relief: Improvement in quality of life by relaxing the prostatic smooth muscle, easing the mechanical symptoms of BPH.
  • Reduced Cardiac Load: By improving systemic flow, the heart is not required to pump against the same level of resistance, preserving cardiovascular longevity.

The Future of Your Vascular Health​

"Gene’s Nitric Oxide Stack" is far from a theoretical exercise; it is a "living protocol" backed by years of community peer-review within the ExcelMale community. The "enormously long" and widely viewed thread on ExcelMale.com serves as a testament to the real-world efficacy of this stack, offering a repository of shared experiences and optimization strategies.

This multi-front approach to anti-aging represents the best of biohacking: using fundamental biological pathways to solve complex aging problems. By focusing on the delivery system itself, we can protect our brains, our hearts, and our vitality simultaneously.

If blood flow is the delivery system for every nutrient your body needs, what happens to your longevity when you finally optimize that system?


More on Nitric Oxide in Men:

Nitric Oxide Pages
 
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Can the citruline or arginine affect liver values - just got results and my ast and alt are really high. The only thing I've changed in my diet is the powdered form of those to control blood pressure which has worked really well.
 
Great Thread .... does this help to increase vascularity in the penis? I'm looking for something specifically localized to increasing vascularity in the penis. I do not have ED but I do have Hypertension.
 
Great Thread .... does this help to increase vascularity in the penis? I'm looking for something specifically localized to increasing vascularity in the penis. I do not have ED but I do have Hypertension.

Improved erection quality over time can lead to better vascularity in the penis in my experience, and this stack did that for me. Manual PE routines can improve it too; there's plenty of info out there on forums about that.
 
Vitamine shoppe.

This is the only place I know where you can get Icariin in the higher dosage (60% vs. 10%) to really get the results this herb can provide:

Icariin 60™ Horny Goat Weed Capsules
Hi Gene,
thank you for presenting this stack I am looking forward to trying it. Question: The icariinhealth product is a 900mg for 3 capsules. so its 300mg each. How do you go about splitting it into the 150 mg dosage you recommend? my body weight is 171 lbs - lean. age 49.
thanks
/k
 
I’m ready to do this stack after just getting prescribed daily Cialis. I’m currently on Flomax, which I take nightly. I’m wondering if adding Doxasosin would be overkill on the alpha blockers. If I were to take the stack I could I omit the doxasosin and use Flomax. Any recommendations would be greatly appreciated. Thanks guys!
 
Hi G! See bold.

Nitric Oxide Stack
Bed Time
5 mg of Tadalafil (Cialis) (Prescription)
3000 mg of L-Arginine
1500 mg of L-Citrulline (Source Naturals L-Arginine L-Citrulline Complex @ Vitamin Shoppe)
50 mg of Pycnogenol (Vitamin Shoppe Brand)
150 mg of Icariin (Horny Goat Weed) (Vitamin Shoppe Brand)
1 mg of Doxazosin (Alpha Blocker) (Prescription)


Morning
3000 mg of L-Arginine
1500 mg of L-Citrulline
50 mg of Pycnogenol
150 mg of Icariin (Horny Goat Weed)



Afternoon
5 mg of Tadalafil (Cialis)
3000 mg of L-Arginine
1500 mg of L-Citrulline
50 mg of Pycnogenol
150 mg of Icariin (Horny Goat Weed)
1 mg of Doxazosin (Alpha Blocker)
Gene- the arginine/citrulline complex will not add up to your total amounts if u take 2 pills 3x a day. Am I misunderstanding?
 
And any IGF-1 panel will prove that out.

I am 3x over the reference range for IGF-1 and I believe this is in part due to the amino stack I take before bed and that includes Arginine and Citrulline as well.
Gene, sermorelin seems to improve vascular ott for me as well as GH levels. Did you stop sermorelin when starting this stack
 
Hey guys, just curious for those experienced members who have been using Gene's Stack. I started taking Ceebis once again after reading this thread and was wondering how everybody went about it starting out. I will probably only use the L-arginine and L-Citriline portions of it with Ceebis, however I will pair it down to maybe once or twice a day.

I started by taking Ceebis 10mg every night which is causing me some issues. One, it's been giving me a splitting headache and sinus pressure, will that eventually leave? Second, I noticed last night that I woke up pretty cold which is usually an indicator that my blood pressure probably dipped too low since I don't suffer from high blood pressure. The only other time that happened was when I popped a large dose of Viagra. Will my body adjust to this or should I titrate down to 5 mg rather than 10mg? The reason I started at 10 was because I used 5 mg before daily and didn't really feel much from it.

Right now I'm using a Pre-workout that is non stimulant and is meant to help with pumps. It's PE Science's High Volume and so far I love it. I'm considering taking supplements in the morning, using my preworkout nitric oxide daily, and only the Ceebis at night. I'm wondering if this will work since I'm not sure I can afford all the pills. I might just buy the powder forms of both, but can I combine them into one drink?

Tons of questions. Thanks for your help ahead of time.
 
I found a reliable supplier of Cialis for the 5mg. Blink Health. Intro for the initial order is $5 for 30 tablets. I will keep you posted on my results for the next month.
 
Bought cialis from peptide site 38$ shipped 30mg/ML for 30ML bottle.

The 90% icariin just look around on amazon itll pop up. Had mixed reviews.
 
Hi G! See bold.

Nitric Oxide Stack
Bed Time
5 mg of Tadalafil (Cialis) (Prescription)
3000 mg of L-Arginine
1500 mg of L-Citrulline (Source Naturals L-Arginine L-Citrulline Complex @ Vitamin Shoppe)
50 mg of Pycnogenol (Vitamin Shoppe Brand)
150 mg of Icariin (Horny Goat Weed) (Vitamin Shoppe Brand)
1 mg of Doxazosin (Alpha Blocker) (Prescription)


Morning
3000 mg of L-Arginine
1500 mg of L-Citrulline
50 mg of Pycnogenol
150 mg of Icariin (Horny Goat Weed)



Afternoon
5 mg of Tadalafil (Cialis)
3000 mg of L-Arginine
1500 mg of L-Citrulline
50 mg of Pycnogenol
150 mg of Icariin (Horny Goat Weed)
1 mg of Doxazosin (Alpha Blocker)
 
It would be really helpful if the original post included recommended sources for the stack.
I'd love to give this stack a try but the cost in Canada is prohibitive for me. The tadalafil, l-arginine and l-citrulline alone are close to $20/day
 

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