Feedback on protocol

firewater

New Member
Hi there, here are some relevant stats and protocols:

I've been on TRT for a year now, SBHG is 20-23.

My most recent protocol had me on 100 mg cyp and 500 IU HCG per week, split e3.5d. I was initially on a higher dose (140 total), but I could never dial it in with arimidex, so I wanted to find a stable dose that didn't require an AI.

My bloods on 140 with no AI had my peak levels at 1.1 and e2 (sensitive) at 44. I was having high e2 sides from this such as: soft erections, holding more water, insomnia, anxiety.

At the recommendation of my clinic, they wanted my trough to be around mid 20s and my peak to be mid 30s. We lowered my dose from 140 to 100 mg in August.

2 weeks after lowering from 140 to 100, I felt GREAT for a period of one week where erections were rock hard and my libido was very very high. However, this was short lived, and by week 6, I was feeling low e2 sides (even with no AI).

I got a blood test at trough during week 6 of 100mg, and my TT was 800, e2 at 19. I was not able to get a full erection even with cialis, was very irritable/angry, and I was a lot more dry looking and veiny.

Based on this, my clinic upped my dose to 60 e3.5 days.

I'm considering doing shots e3d instead of 3.5 due to my schedule. I've been on 120 mg now for 2 weeks, and I'm not seeing much improvements. Should I just ride out 120 mg for another month and then get bloods or go to 50 mg e3d?

My thinking is that 120 mg over 7 and 100 mg over 6 should give similar amounts of test.

Thanks for any feedback
 
As far as changing your protocol again, minimum is 4 weeks, preferably 6 before drawing blood again.
No reason you couldn't go every 3 days.
I switched from every 3.5 days to an EOD/MWF injection schedule and personally like it.
It's great that your doc is working with you and willing to make changes based on how your feeling as well as monitoring bloodwork.
Just make sure you note your changes with them and keep trying to work it out.
Often times it takes guys awhile to find that optimal protocol, so don't get frustrated.
As everyone one here will tell you it's much more of a marathon than a sprint.
You're on the right path.
 

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HCG Mixing Protocol Calculator

TRT Hormone Predictor Widget

TRT Hormone Predictor

Predict estradiol, DHT, and free testosterone levels based on total testosterone

⚠️ Medical Disclaimer

This tool provides predictions based on statistical models and should NOT replace professional medical advice. Always consult with your healthcare provider before making any changes to your TRT protocol.

ℹ️ Input Parameters

Normal range: 300-1000 ng/dL

Predicted Hormone Levels

Enter your total testosterone value to see predictions

Results will appear here after calculation

Understanding Your Hormones

Estradiol (E2)

A form of estrogen produced from testosterone. Important for bone health, mood, and libido. Too high can cause side effects; too low can affect well-being.

DHT

Dihydrotestosterone is a potent androgen derived from testosterone. Affects hair growth, prostate health, and masculinization effects.

Free Testosterone

The biologically active form of testosterone not bound to proteins. Directly available for cellular uptake and biological effects.

Scientific Reference

Lakshman KM, Kaplan B, Travison TG, Basaria S, Knapp PE, Singh AB, LaValley MP, Mazer NA, Bhasin S. The effects of injected testosterone dose and age on the conversion of testosterone to estradiol and dihydrotestosterone in young and older men. J Clin Endocrinol Metab. 2010 Aug;95(8):3955-64.

DOI: 10.1210/jc.2010-0102 | PMID: 20534765 | PMCID: PMC2913038

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