Experimenting with Arimidex when drinking alcohol

I have been on TRT for 9 months (age 28), but have found that it doesn't mix with alcohol well. I've only drunk 3 times, but each time I get what feels like an estrogen hangover that lasts for a couple of days. I don't have blood tests to prove this, but when I drink I get acute bloating, acne and a bit of anxiety (despite the fact I'm drinking). This has costed me socially quite a bit, and I would like to be able to drink socially occasionally. I contacted my doctor who says that he gets the odd patient who reports these symptoms when drinking but doesn't understand why it happens. I asked if I could try an AI just to see if it works, so he has prescribed arimidex as he doesn't see much harm in me trying.

Let's say this actually worked. If I took arimidex occasionally when drinking, would I suffer from an estrogen rebound effect of one dose?
 

hCG Mixing Calculator

HCG Mixing Protocol Calculator

TRT Hormone Predictor Widget

TRT Hormone Predictor

Predict estradiol, DHT, and free testosterone levels based on total testosterone

⚠️ Medical Disclaimer

This tool provides predictions based on statistical models and should NOT replace professional medical advice. Always consult with your healthcare provider before making any changes to your TRT protocol.

ℹ️ Input Parameters

Normal range: 300-1000 ng/dL

Predicted Hormone Levels

Enter your total testosterone value to see predictions

Results will appear here after calculation

Understanding Your Hormones

Estradiol (E2)

A form of estrogen produced from testosterone. Important for bone health, mood, and libido. Too high can cause side effects; too low can affect well-being.

DHT

Dihydrotestosterone is a potent androgen derived from testosterone. Affects hair growth, prostate health, and masculinization effects.

Free Testosterone

The biologically active form of testosterone not bound to proteins. Directly available for cellular uptake and biological effects.

Scientific Reference

Lakshman KM, Kaplan B, Travison TG, Basaria S, Knapp PE, Singh AB, LaValley MP, Mazer NA, Bhasin S. The effects of injected testosterone dose and age on the conversion of testosterone to estradiol and dihydrotestosterone in young and older men. J Clin Endocrinol Metab. 2010 Aug;95(8):3955-64.

DOI: 10.1210/jc.2010-0102 | PMID: 20534765 | PMCID: PMC2913038

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