Doc wants me on HCG 1000 IU- 1500IU 3x a week.
Is there any reliable study out there that backs this as evidence.
Doc that states he would like to keep my Fertility system alive. He would like half testerone to be exogenous and half endogenous.
I haven't read any study online which says this to be true?
Most pro fertility protocols are either
Test (100-200mg week) + HCG 250-500 3x a week or EOD
I would like to keep my fertility system alive while on TRT but nothing I see online backs the doctors claim
Is there anyone here that can provide insight on this?
Doc wants me on HCG 1000 IU- 1500IU 3x a week.
This is overkill off the hop!
Even then many can maintain/preserve fertility using lower weekly doses.
Doc that states he would like to keep my Fertility system alive. He would like half testerone to be exogenous and half endogenous.
Does not work like this as the main driver for increasing your T when using exogenous T + hCG is the testosterone.
Yes you will also get a bump in T and estradiol depending on the dose used when adding in the hCG but the bump in T will not be significant.
The main purpose of adding hCG when using exogenous T is to preserve/maintain fertility and prevent/minimize testicular atrophy.
The use of exogenous testosterone results in the suppression of ITT (intra-testicular testosterone) which is critical for sperm production.
Hcg mimics LH and will keep the Leydig cells active (producing some degree of ITT).
The main goal when using hCG is to restore physiological ITT levels and in order to achieve such a minimum effective dose would be needed (125-500 IU) and 250-500 IU would be the sweet spot to stimulate maximum ITT (intratesticular testosterone) production which should have a strong impact on minimizing/preventing testicular atrophy and maintaining fertility.
If you want to maintain fertility let alone prevent/minimize testicular atrophy 250-500IU 3X weekly or EOD would suffice.
Even then keep in mind when it comes to sperm production some men will need much higher doses of hCG and if this does not do the trick then FSH would be thrown in.
You should have had an SA done before you jumped on T so you would know where your baseline sat.
Any doctor in the know treating a man for low-T that wanted to preserve/maintain fertility would tell you that it would be in your best interest to get a. baseline SA or freeze sperm if need be!
Human chorionic gonadotropin treatment: a viable option for management of secondary hypogonadism and male infertility (2020)
Julius Fink, Brad J. Schoenfeld, Anthony C. Hackney, Takahiro Maekawa & Shigeo Horie
Abstract
Introduction: Low testosterone and its symptoms is a condition affecting many males with severe repercussions on health. Testosterone affects metabolism, bones, joints and ligaments, the cardiovascular system, liver, sexual functions, muscle mass, and the nervous system. Nowadays, due to recent research showing the benefits of testosterone replacement...
Fertility Preservation in Hypogonadal Men (2018)
Robert J. Carrasquillo and Ranjith Ramasamy
Introduction
Testicular failure is defined as the impairment or loss of both the endocrine functions of the testis (production of testosterone, or T) and exocrine function (production of spermatozoa). Testicular failure can result from the pathology of the testis itself or disorder at any point in the hypothalamic-pituitary-gonadal axis. Primary testicular failure is characterized by normal/low T in the presence of the elevated follicle-stimulating hormone...
