DHEA and Pregnenolone cream vs pill m

[munch520]

I have Hashimotos Thyroiditis, along with some low LH/FSH and low free testosterone...I've had two docs with two different schools of thought address the LH/FSH and low free T (total T is great).

Doc 1: Prescribed oral DHEA and Pregnenolone. The DHEA came from an off book pharmacy (can't remember dose), the Preg is 10mg/pill from Pure Encapsulations.
Doc 2: Says that taking these orally is stupid, the dosage is millions of times higher than the body needs, so he says the liver will react to this influx of hormone by creating more SHBG, further lowering my free T levels. He says a cream (or basically anything other than oral) is much better, as the skin absorbs in much smaller concentrations, and this will avoid the reaction from the liver. This will allow the hormones to do their job, without any adverse affects on free T.

Approach #2 makes sense to me, anyone else compared the two delivery methods? What were your experiences? Should I also be considering sublingual?

Thanks in advance!

 

[Vince Carter]

There can be interaction in the liver where DHEA can aromatase, TD is preferred, but the oral micro-nized versions of both pro-hormones are most likely to survive first pass thru the liver. I haven't seen a dosing difference in the capsules and TD.

 

[munch520]

OK thanks I will look into that and the sublingual. The latter is substantially cheaper than the cream and I would think dosage would be more stable going that route...

 

[trt4me]

Oral absorbtion I'm told has varied a lot from person to person.
I can take anything off the shelf orally and get great results and never had an effect on shbg. Sublingual is also a great method.