COVID-19 and men’s health: What we know so far

[madman]

COVID-19 and men’s health: What we know so far

According to recently published studies, having COVID-19 could have lasting impacts on fertility and sexual function.

www.urologytimes.com

Studies are beginning to suggest that COVID-19’s impact on men’s health might go beyond the lungs, heart, and kidneys. According to recently published studies, having COVID-19 could have lasting impacts on fertility and sexual function.

Ranjith Ramasamy, MD, associate professor and director of the University of Miami Miller School of Medicine’s Reproductive Urology Program, is uncovering what he says are clear links between COVID-19 infection and men’s sexual health.

“We know the COVID-19 virus can remain inside the testis long after the initial infection in asymptomatic men. We know the COVID-19 virus can decrease sperm count for up to 3 to 6 months. And we know the COVID-19 virus can affect the blood vessels and be present in the penis up to 7 to 9 months after the initial infection and can lead to erectile dysfunction,” Ramasamy said.

Getting the mRNA COVID-19 vaccine does not appear to impact fertility and should be encouraged, according to Ramasamy, who has published several articles on COVID-19 and men’s sexual health, including the research letter, “Sperm parameters before and after COVID-19 mRNA vaccination” published June 17 in JAMA.1


*COVID-19 and male infertility

*The evolving science of covid-19 and ed

*Putting the information to practice

*Ongoing research

 

[Nelson Vergel]

A study looking at the impact of the COVID-19 vaccine on male fertility

University of Miami Miller School of Medicine researchers have begun recruiting for a study looking at the impact of the COVID-19 vaccine on male fertility. https://physician-news.umiamihealth.org/miller-school-researchers-recruiting-for-study-on-covid-19-vaccine-and-male-fertility/ The...

www.excelmale.com

 

[Nelson Vergel]

Does Testosterone Make COVID-19 Worse?

Interested to see thoughts here. I am still wondering about the high prevalence of COVID-19 in males. What is it? Lifestyle choices - smoking, alcohol use, the likelihood of other comorbidities, like high blood pressure, diabetes, obesity...

www.excelmale.com

 

[Nelson Vergel]

Testosterone in COVID-19: Friend or Foe?

Coronavirus disease 2019 (COVID-19) as an ongoing disruptive pandemic poses significant challenges for the clinician. The pathogen responsible for COVID-19 is severe acute respiratory syndrome coronavirus-2 (SARS-CoV2). Although it is primarily a viral infection that affects the lower...

www.excelmale.com

 

[Nelson Vergel]

Why the Coronavirus Seems to Hit Men Harder Than Women...Estrogen Levels?

Maybe one more reason to let your Estrogen levels rise when doing TRT. Although men and women have been infected in roughly equal numbers, researchers found, the death rate among men was 2.8 %, compared with 1.7% among women.... could Estrogen levels be the key to the difference? Link To...

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[Nelson Vergel]

BJU Int. 2021 Aug 17. doi: 10.1111/bju.15573. Online ahead of print.

Impact of the SARS-CoV-2 Virus on Male Reproductive Health

Daniel E Nassau 1, Jordan C Best 1, Eliyahu Kresch 1, Daniel C Gonzalez 1, Kajal Khodamoradi 1, Ranjith Ramasamy 1

Affiliations expand

PMID: 34402155 DOI: 10.1111/bju.15573

Abstract

The Coronavirus 2019 (COVID-19) pandemic caused by the novel severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) has led to more than 160 million infections and 3.5 million deaths globally. Men are disproportionately affected by COVID-19, having more severe disease with higher mortality rates than women. Androgens have been implicated as the underlying cause for more severe disease, as the androgen receptor has been noted to upregulate the cell surface receptors that mediate viral cell entry and infection. Unfortunately, despite testosterone's potential role in COVID-19 prognosis, androgen deprivation therapy is neither protective nor a treatment for COVID-19. Interestingly, the male reproductive organs have been found to be vulnerable in moderate to severe illness, leading to reports of erectile dysfunction and orchitis. COVID-19 viral particles have been identified in penile and testis tissue, both in live patients who recovered from COVID-19 and post-mortem men who succumbed to the disease. Although sexual transmission remains unlikely in recovered men, moderate to severe COVID-19 infection can lead to germ cell and Leydig cell depletion, leading to decreased spermatogenesis and male hypogonadism. The objective of this review is to describe the impact of SARS-CoV-2 on male reproductive health. There are still many unanswered questions as to the specific underlying mechanisms by which COVID-19 impacts male reproductive organs and the long-term sequalae of SARS-CoV-2 on male reproductive health.

 

[Nelson Vergel]

COVID-19 and Male Infertility and Erectile Dysfunction

www.excelmale.com

 

[Nelson Vergel]

COVID-19 and the Endocrine System: A Comprehensive Review on the Theme

Background and aim. The review aimed to summarize advances in the topic of endocrine diseases and coronavirus disease 2019 (COVID-19). Methods. Scientific and institutional websites and databases were searched and data were collected and organized, when plausible, to angle the discussion toward...

www.mdpi.com

 

[Nelson Vergel]

COVID-19 Infection in Men on Testosterone Replacement Therapy (TRT)

https://www.discountedlabs.com/blog/covid-19-infection-in-men-on-testosterone-replacement-therapy-trt

www.excelmale.com

 

[Nelson Vergel]

Oral Testosterone, Testosterone and COVID, and TRT Myths

Mohit Khera, MD, MBA, MPH, discusses testosterone therapy options for COVID-19, prostate cancer, and more.

www.excelmale.com

 

[Mawwewyss]

I also faced this problem, I couldn't find good nitrile gloves for a long time.

 

[Nelson Vergel]

Niger J Clin Pract. 2022 Nov;25(11):1812-1815. doi: 10.4103/njcp.njcp_188_22.

Do the Covid-19 vaccines affect the reproductive parameters of men?-A Northern Saudi experience

M J Alenzi 1, E E Ikpi 2, A S Alshlash 1, S M Alkhaldi 1, Z N Aljazi 1, M Alrawili 3, S Alanazi 4, J A Alenazi 3


PMID: 36412287 DOI: 10.4103/njcp.njcp_188_22

Abstract
Background: The COVID-19 vaccine acceptance is a psychological behavior influenced by many factors, including fear of an adverse effect on the reproductive system.

Aims: The aim of this study is to assess the COVID-19 vaccines effect on reproductive parameters among the male population of northern Saudi Arabia.

Patients and methods: We conducted a prospective cohort study among 100 volunteers who received two doses of COVID-19 vaccines. A pre- and post-vaccination blood sample was collected and analyzed for testosterone, prolactin, and follicle-stimulating hormone (FSH). Semen samples were also collected and analyzed. The Wilcoxon signed-rank test was used to compare the values between pre- and post-vaccination.

Results: Of the 100 samples analyzed, there was a significant increase in progressive sperm motility after the second dose of vaccination, but the increase was within the physiological limits (pre-55.03 [42.00-61.75] vs. post-57.50 [42.25-63.00], P = 0.008). Similarly, a significant increase in serum testosterone level after the second vaccination dose was observed (pre-380.65 [301.60-485.73] vs. post-410 [318.18-505.35], P = 0.016).

Conclusion: These preliminary results show that the COVID-19 vaccines do not have any adverse effect on the reproductive parameters of men. A prospective long-term follow-up study will be necessary on all WHO -approved COVID vaccines to determine their long-term effect on men's reproductive health. The future follow-up study could strengthen our findings and encourage the men who have vaccine hesitancy to take due to fear of its effect on reproductive parameters.

Keywords: COVID-19 vaccines; reproductive parameters; sperm count; testosterone.