COVID-19 Infection is not Worse in Men on Testosterone Replacement Therapy

[Nelson Vergel]

COVID-19 Infection in Men on Testosterone Replacement Therapy

Abstract
Men who contract Coronavirus Disease 2019 (COVID-19) appear to have worse clinical outcomes compared to women which raises the possibility of androgen dependent effects. We sought to determine if testosterone replacement therapy (TRT) is associated with worse clinical outcomes. Through a retrospective chart review, we identified 32 men diagnosed with COVID-19 and on TRT. They were propensity score matched to 63 men diagnosed with COVID-19 and not on TRT. Data regarding comorbidities and endpoints such as hospital admission, intensive care unit (ICU) admission, ventilator utilization, thromboembolic events, and death were extracted. Chi-square and Kruskal-Wallis tests examined differences in categorical and continuous variables, respectively. Logistic regression analysis tested the relationship between TRT status and the study endpoints. There were no statistically significant differences between the two groups and TRT was not a predictor of any of the endpoints on multivariate analysis. These results suggest that TRT is not associated with a worse clinical outcome in men diagnosed with COVID-19.

COVID-19 in Men on Testosterone

 

[Nelson Vergel]

Why the Coronavirus Seems to Hit Men Harder Than Women...Estrogen Levels?

Maybe one more reason to let your Estrogen levels rise when doing TRT. Although men and women have been infected in roughly equal numbers, researchers found, the death rate among men was 2.8 %, compared with 1.7% among women.... could Estrogen levels be the key to the difference? Link To...

www.excelmale.com

 

[Nelson Vergel]

Does Testosterone Make COVID-19 Worse?

Interested to see thoughts here. I am still wondering about the high prevalence of COVID-19 in males. What is it? Lifestyle choices - smoking, alcohol use, the likelihood of other comorbidities, like high blood pressure, diabetes, obesity...

www.excelmale.com

 

[Nelson Vergel]

Viral pathogenesis of SARS-CoV-2 infection and male reproductive health

Coronavirus disease 2019 (COVID-19) has emerged as a new public health crisis, threatening almost all aspects of human life. Originating in bats, severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) is transmitted to humans through unknown intermediate hosts, where it is primarily known...

www.excelmale.com

 

[Nelson Vergel]

Testosterone in COVID-19: Friend or Foe?

Coronavirus disease 2019 (COVID-19) as an ongoing disruptive pandemic poses significant challenges for the clinician. The pathogen responsible for COVID-19 is severe acute respiratory syndrome coronavirus-2 (SARS-CoV2). Although it is primarily a viral infection that affects the lower...

www.excelmale.com

 

[Nelson Vergel]

COVID-19 and Impotence: There Seems to be a Connection, but How Strong Is It?

Data shows some association with erectile dysfunction, but more research needed

www.medpagetoday.com