Could hCG or LH spikes cause blood sugar drops??

phalloguy100

Active Member
OK, so this is totally based on my own experience… I’ve noticed that I have huge, sudden drops in blood sugar (as much as 140 mg/dL) a few minutes after each hcg sub-q shot. The drops don’t last long though so they’re not a big concern- my glucose stabilizes within an hour or so on its own.

But as far as I know, hcg is NOT supposed to cause hypoglycemia or any kind of sugar drop. I suspect it may have something to do with insulin sensitivity, since I have type 2 diabetes.

I think this has been happening every time since restarting hcg last year, but it wasn’t until recently that I was able to make the connection because I started doing the shots at night for convenience, at which time I hadn’t exercised so there would be no reason for mu sugar to drop. And it’s not a “compression low” on the CGM (false low readings when you lay on your arm) because I wasn’t laying down.

Any theories? Is there any relationship between hcg/TRT/e2/LH/T and blood glucose/insulin/glucagon?

See example below from my Dexcom CGM. The top of that second spike is just around the time when I injected hCG.
 

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Estradiol (E2)

A form of estrogen produced from testosterone. Important for bone health, mood, and libido. Too high can cause side effects; too low can affect well-being.

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Dihydrotestosterone is a potent androgen derived from testosterone. Affects hair growth, prostate health, and masculinization effects.

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The biologically active form of testosterone not bound to proteins. Directly available for cellular uptake and biological effects.

Scientific Reference

Lakshman KM, Kaplan B, Travison TG, Basaria S, Knapp PE, Singh AB, LaValley MP, Mazer NA, Bhasin S. The effects of injected testosterone dose and age on the conversion of testosterone to estradiol and dihydrotestosterone in young and older men. J Clin Endocrinol Metab. 2010 Aug;95(8):3955-64.

DOI: 10.1210/jc.2010-0102 | PMID: 20534765 | PMCID: PMC2913038

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