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Weak4IceCream

New Member
Hello all, I am very happy to find this forum.

To make a long story short, i was diagnosed with Hypogonadism a few months back. I am 28, 6'3 and 190lbs. I don't smoke/drink and lead an active life. My first test showed my Test at 404 ng/dL (ref. range is 264-916 ng/dL), as well as very low FSH(1.2 mIU/mL from a reference range of 1.5-12.4) . Estradiol and Prolactin were normal. My second test showed a Test value of 286 ng/DL. My doctor prescribed me Clomid, i was skeptical about it but I did not want to get on injections just yet due to my age and the fact that my wife and I want to conceive this year. My doctor also talked about the mental side of things, since all my symptoms initially started with a bad streak of sudden premature ejaculation and that kind of got in my head, but the symptoms of low T appeared pretty quickly afterwards. Anyways, I got on 50 mg/3 times a week.

After starting Clomid, the only thing that got better was my mood, and even that was only so slightly. I don't think I've felt any physical differences, and if anything I got more moody. A month later I re-did my tests, Test increased to 923ng/dL and FSH to 2.1 (though not a big increase, still puts me in the "normal" range). The doctor wants to keep me on Clomid, despite me not feeling a single bit better, neither my libido nor my erections have recovered, and my premature ejaculation continues. Its been very uncomfortable. Im going to stop taking Clomid but i am back at square one.

Those who've dealt with secondary hypogonadism or a similar case, what has helped you? I don't want to jump on TRT just yet, but are there any other options that i can discuss with another specialist?
I guess I am also just looking to see that im not alone in this.

Thank you all and God bless.
 

Systemlord

Member
Clomid isn’t going to be the solution for you, many other’s have had similar experiences.

You’re not alone.

HCG is another option, but will shutdown your HPTA but may help keep you fertile.

You can also add FSH injections in conjunction with hCG to significantly improve your chances at getting sperm count ^^..

Natesto nasal spray might be another option, it doesn’t shut you down, adds to your natural production.
 
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Weak4IceCream

New Member
Clomid isn’t going to be the solution for you, many other’s have had similar experiences.

You’re not alone.

HCG is another option, but will shutdown your HPTA but may help keep you fertile.

You can also add FSH injections in conjunction with hCG to significantly improve your chances at getting sperm count ^^..

Natesto nasal spray might be another option, it doesn’t shut you down, adds to your natural production.
Thanks for this reply, the odd part of it all is that the sperm analysis showed nothing but good results, so no problem (so far!) with sperm production. But there's low ejaculate volume, EQ has suffered, and erections wont happen without cialis. I have no idea what to make of this whole situation. I am suffering from low energy, depression and general fatigue on top of other symptoms.

HCG monotherapy seems promising, however I don't know enough about it. And this is also the first time im hearing FSH injections. You've given me some things to look up.

Thank you so much.
 

Weak4IceCream

New Member
HCG mimics LH, the stimulating hormone for the testicles to make testosterone. FSH is the stimulating hormone for the testicles to make sperm.
Im aware of their functions, I did not know you could get injectible FSH.

Main question though is by using HCG you would bypass the pituitary mechanism (that is not functioning) to simulate the testes correct?
 

Guided_by_Voices

Well-Known Member
A few things...

- I don't see the dose of clomid. I started with clomid and the only protocol that gave me good results was 12mg every other day. Also, if you decide to try this does and you are above that dose now, I found I had to do a complete wash-out of a month or so and then restart at the lower dose given the long time that clomid persists in the body.

- I am not the expert on PE but I assume you have tried de-sensitizing agents, and there is now a pill for PE which I don't recall the name of right now but it is easily available via mail, although not "officially" available in the US. It is a fast-acting SSRI though so something to go slow with like everything else.

- Your symptoms sound like something that would benefit from a work-up from a good holistic doctor since fatigue etc. sounds like it could be some sort of infection, mold exposure, or environmental toxin.

- If you decide to experiment with TRT, I would go with one of the very fast-acting (and hence minimally suppressive) modalities that I think @Cataceous is an expert in. That should at least provide a proof-of-concept at minimal risk.
 

Vince

Super Moderator
One of my son-in-laws wanted to get this wife pregnant for the 6th time. He's 46 now. He took 50 mg of clomid daily for 2 weeks that off for one week then back on for 2 weeks until his wife was pregnant. His wife is only 36 but she also used clomid I'm not sure exactly what was her protocol.
 

Weak4IceCream

New Member
A few things...

- I don't see the dose of clomid. I started with clomid and the only protocol that gave me good results was 12mg every other day. Also, if you decide to try this does and you are above that dose now, I found I had to do a complete wash-out of a month or so and then restart at the lower dose given the long time that clomid persists in the body.

- I am not the expert on PE but I assume you have tried de-sensitizing agents, and there is now a pill for PE which I don't recall the name of right now but it is easily available via mail, although not "officially" available in the US. It is a fast-acting SSRI though so something to go slow with like everything else.

- Your symptoms sound like something that would benefit from a work-up from a good holistic doctor since fatigue etc. sounds like it could be some sort of infection, mold exposure, or environmental toxin.

- If you decide to experiment with TRT, I would go with one of the very fast-acting (and hence minimally suppressive) modalities that I think @Cataceous is an expert in. That should at least provide a proof-of-concept at minimal risk.
The dose is 50mg 3 times a week.
As far as the sypmtoms, they are in line with low testosterone. And now I got Clomid making me feel like crap on top, but im detoxing from it.
Thanks for the reply and thoughts.
 

Guided_by_Voices

Well-Known Member
The dose is 50mg 3 times a week.
As far as the sypmtoms, they are in line with low testosterone. And now I got Clomid making me feel like crap on top, but im detoxing from it.
Thanks for the reply and thoughts.
The PE pill is Dapoxetine. 150mg per week is an astronomical dose for many people and IMO/IME invalidates any conclusions, good or bad, about clomid.
 

Weak4IceCream

New Member
The PE pill is Dapoxetine. 150mg per week is an astronomical dose for many people and IMO/IME invalidates any conclusions, good or bad, about clomid.
Currently on my Clomid Detox. I didn't feel any better, and i don't think adjusting the dose will do me any good. I am going to let it taper off from my system and do another test.

Thank you for the PE pill suggestion, i will try to find it from an online pharmacy to ship to Houston.
 

Dog427

Member
Hello all, I am very happy to find this forum.

To make a long story short, i was diagnosed with Hypogonadism a few months back. I am 28, 6'3 and 190lbs. I don't smoke/drink and lead an active life. My first test showed my Test at 404 ng/dL (ref. range is 264-916 ng/dL), as well as very low FSH(1.2 mIU/mL from a reference range of 1.5-12.4) . Estradiol and Prolactin were normal. My second test showed a Test value of 286 ng/DL. My doctor prescribed me Clomid, i was skeptical about it but I did not want to get on injections just yet due to my age and the fact that my wife and I want to conceive this year. My doctor also talked about the mental side of things, since all my symptoms initially started with a bad streak of sudden premature ejaculation and that kind of got in my head, but the symptoms of low T appeared pretty quickly afterwards. Anyways, I got on 50 mg/3 times a week.

After starting Clomid, the only thing that got better was my mood, and even that was only so slightly. I don't think I've felt any physical differences, and if anything I got more moody. A month later I re-did my tests, Test increased to 923ng/dL and FSH to 2.1 (though not a big increase, still puts me in the "normal" range). The doctor wants to keep me on Clomid, despite me not feeling a single bit better, neither my libido nor my erections have recovered, and my premature ejaculation continues. Its been very uncomfortable. Im going to stop taking Clomid but i am back at square one.

Those who've dealt with secondary hypogonadism or a similar case, what has helped you? I don't want to jump on TRT just yet, but are there any other options that i can discuss with another specialist?
I guess I am also just looking to see that im not alone in this.

Thank you all and God bless.
Long story short. At first, Clomid did not come anywhere near helping me. Needed injection testosterone and for me I did not feel better over 800 mg/dl.

Years later no problems.

We are all different. I think Doctors try Clomid first to justify testosterone later.
 

Weak4IceCream

New Member
Update:

Went to a new endo and got a full panel done.

TSH+Free T4 : 4.20 Ref range:0.40-4.50 mIU/L
T4: 1.4 Ref Range:0.8-1.8 ng/dL

FSH: 1.1 Ref Range: 1.4 - 12.8 mIU/mL
LH: 2.7 Ref Range: 1.5 - 9.3 mIU/mL

Free Test: 75.4 Ref Range:46.0 - 224.0 pg/mL
Total Test: 479 Ref Range 250 - 1100 ng/dL

Overall, everything else looks normal the FSH is low again after my Clomid Detox. The sperm analysis came back fine, so fertility will not be an issue for the time being since we are trying to conceive. But my mood is still not where it was and things are a bit different. I am feeling OK though. I plan to conceive and then go on TRT because I am genuinely not feeling "normal" and don't really buy the endo's "Everything looks fine, let's see if fertility is impacted or not". This whole thing has me confused, but I appreciate everyone here and your input.
 

Systemlord

Member
I am genuinely not feeling "normal" and don't really buy the endo's "Everything looks fin
A lot of doctors don't care about symptoms or lack thereof, they only care about labs ranges. Doctors spend the majority of their time reviewing lab ranges of their patients, keeping everyone within range and calling it a day.

For some doctors, it's just a job, nothing more. Some are in it for the money and it seems few truly have a passion for helping people feel better.
 
A few things...

- I don't see the dose of clomid. I started with clomid and the only protocol that gave me good results was 12mg every other day. Also, if you decide to try this does and you are above that dose now, I found I had to do a complete wash-out of a month or so and then restart at the lower dose given the long time that clomid persists in the body.

- I am not the expert on PE but I assume you have tried de-sensitizing agents, and there is now a pill for PE which I don't recall the name of right now but it is easily available via mail, although not "officially" available in the US. It is a fast-acting SSRI though so something to go slow with like everything else.

- Your symptoms sound like something that would benefit from a work-up from a good holistic doctor since fatigue etc. sounds like it could be some sort of infection, mold exposure, or environmental toxin.

- If you decide to experiment with TRT, I would go with one of the very fast-acting (and hence minimally suppressive) modalities that I think @Cataceous is an expert in. That should at least provide a proof-of-concept at minimal risk.
Please can you tell us a bit more about what you experienced with Clomid at 12mg every other day? And what changed when you changed the dosage?
 
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