Cialis and Alcohol

[SkyWarn]

I tried Cialis four or five years ago, and I noticed it was making my heart race a little. I recently gave it another try 2.5 mg every day and I’m no longer feeling that side effect. I think part of the reason is because lately my blood pressure has been a little bit on the high side so I think the Cialis is helping bring my pressure down, but I do have one concern. Sometimes I like to go out for a few drinks two or three margaritas etc. have not tried that yet.. anyone experience any side effects while drinking and on Cialis?
Also, I need to get an updated prescription. The Cialis that I’m taking right now expired four years ago.

 

[Wilson7]

Headache. I've used 4 yr exp cialis, worked just fine.

 

[madman]

I tried Cialis four or five years ago, and I noticed it was making my heart race a little. I recently gave it another try 2.5 mg every day and I’m no longer feeling that side effect. I think part of the reason is because lately my blood pressure has been a little bit on the high side so I think the Cialis is helping bring my pressure down, but I do have one concern. Sometimes I like to go out for a few drinks two or three margaritas etc. have not tried that yet.. anyone experience any side effects while drinking and on Cialis?
Also, I need to get an updated prescription. The Cialis that I’m taking right now expired four years ago.

*Substantial consumption of alcohol (e.g., 5 units or greater) in combination with CIALIS can increase the potential for orthostatic signs and symptoms, including increase in heart rate, decrease in standing blood pressure, dizziness, and headache




-------------------------------DRUG INTERACTIONS------------------------------

• CIALIS can potentiate the hypotensive effects of nitrates, alpha blockers, antihypertensives or alcohol (7.1).


Alcohol — Both alcohol and tadalafil, a PDE5 inhibitor, act as mild vasodilators. When mild vasodilators are taken in combination, blood-pressure-lowering effects of each individual compound may be increased. Substantial consumption of alcohol (e.g., 5 units or greater) in combination with CIALIS can increase the potential for orthostatic signs and symptoms, including increase in heart rate, decrease in standing blood pressure, dizziness, and headache. Tadalafil did not affect alcohol plasma concentrations and alcohol did not affect tadalafil plasma concentrations. [see Warnings and Precautions (5.9) and Clinical Pharmacology (12.2)].




12.2 Pharmacodynamics

Effects on Blood Pressure

Tadalafil 20 mg administered to healthy male subjects produced no significant difference compared to placebo in supine systolic and diastolic blood pressure (difference in the mean maximal decrease of 1.6/0.8 mm Hg, respectively) and in standing systolic and diastolic blood pressure (difference in the mean maximal decrease of 0.2/4.6 mm Hg, respectively). In addition, there was no significant effect on heart rate.




Effects on Blood Pressure When Administered with Alcohol

Alcohol and PDE5 inhibitors, including tadalafil, are mild systemic vasodilators. The interaction of tadalafil with alcohol was evaluated in 3 clinical pharmacology studies. In 2 of these, alcohol was administered at a dose of 0.7 g/kg, which is equivalent to approximately 6 ounces of 80-proof vodka in an 80-kg male, and tadalafil was administered at a dose of 10 mg in one study and 20 mg in another. In both these studies, all patients imbibed the entire alcohol dose within 10 minutes of starting. In one of these two studies, blood alcohol levels of 0.08% were confirmed. In these two studies ,more patients had clinically significant decreases in blood pressure on the combination of tadalafil and alcohol as compared to alcohol alone. Some subjects reported postural dizziness, and orthostatic hypotension was observed in some subjects. When tadalafil 20 mg was administered with a lower dose of alcohol (0.6 g/kg, which is equivalent to approximately 4 ounces of 80-proof vodka, administered in less than 10 minutes), orthostatic hypotension was not observed, dizziness occurred with similar frequency to alcohol alone, and the hypotensive effects of alcohol were not potentiated.

 

[Vince]

I tried Cialis four or five years ago, and I noticed it was making my heart race a little. I recently gave it another try 2.5 mg every day and I’m no longer feeling that side effect. I think part of the reason is because lately my blood pressure has been a little bit on the high side so I think the Cialis is helping bring my pressure down, but I do have one concern. Sometimes I like to go out for a few drinks two or three margaritas etc. have not tried that yet.. anyone experience any side effects while drinking and on Cialis?
Also, I need to get an updated prescription. The Cialis that I’m taking right now expired four years ago.

I buy from reliable RX.

Cialis\Tadalafil way too expensive at drugstore in canada, any reputable website for it ?

i need to use 5mg daily cialis (generic) for ED. the cheapest i can get at drugstore here in quebec, canada is 65$ for 4x20mg (so 16x5mg) it would cost 130$ per month. and more if i want to up the dose. Im lost and absolutely scared to order on those online shady website but that is my onlu...

www.excelmale.com