can testosterone cause anxiety

and you believe trt caused them ? Just curious cause I have some weird shit on trt also

I have continued to have these deficiencies off TRT, however not to the same extent. I believe there is an underlying issue causing the deficiencies. If I restart TRT, attempt to treat diabetes and/or attempt to treat the high blood pressure or become metabolically active, it ends in a deficiency.

Any one of these will cause some sort of deficiency vitamin C and/or potassium. My endo is going to have my wear a device for 2 weeks to monitor insulin levels. I believe whatever is causing these deficiencies is what caused my low testosterone and is why TRT has failed me so many times.
 
The short answer is yes.

Trt can cause anxiety, but this is the exception. Research actually indicates the opposite is more common.

Patients with testosterone deficit syndrome and depression. - PubMed - NCBI

An increase in testosterone and TRT specifically has been positively correlated with a decrease in psychiatric conditions such as depression and anxiety.

More than likely you just need to be better dialed in with your protocol.

I'd imagine that there is a decent margin of error with dosage using a cream from a compounding pharmacy relative to traditional IM...

Keep in mind that this is just speculation.

Have you ever considered IM?
 

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TRT Hormone Predictor

Predict estradiol, DHT, and free testosterone levels based on total testosterone

⚠️ Medical Disclaimer

This tool provides predictions based on statistical models and should NOT replace professional medical advice. Always consult with your healthcare provider before making any changes to your TRT protocol.

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Understanding Your Hormones

Estradiol (E2)

A form of estrogen produced from testosterone. Important for bone health, mood, and libido. Too high can cause side effects; too low can affect well-being.

DHT

Dihydrotestosterone is a potent androgen derived from testosterone. Affects hair growth, prostate health, and masculinization effects.

Free Testosterone

The biologically active form of testosterone not bound to proteins. Directly available for cellular uptake and biological effects.

Scientific Reference

Lakshman KM, Kaplan B, Travison TG, Basaria S, Knapp PE, Singh AB, LaValley MP, Mazer NA, Bhasin S. The effects of injected testosterone dose and age on the conversion of testosterone to estradiol and dihydrotestosterone in young and older men. J Clin Endocrinol Metab. 2010 Aug;95(8):3955-64.

DOI: 10.1210/jc.2010-0102 | PMID: 20534765 | PMCID: PMC2913038

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