Bringing dhea levels up
- Thread starter tmckenzie
- Start date
Gene Devine
Super Moderator
Dr. Neal Rouizer has a great presentation on DHEA that I have in a paper here but I will post here as well.
There is a big deal on the type of pill you take. DHEA and Pregnenolone are best taking in a ultra micronized slow release formula. This provides for better uptake and due to short half life insures one is getting what they need through the course of the day.
Here's Dr. Rouizer's presentation, enjoy fellows:
DHEA Supplementation
Dehydroepiandrosterone: DHEA
As presented by Dr. Neal Rouzier, M.D.
Here's a great reason to add DHEA to your protocol.
DHEA is a hormone secreted primarily by the adrenal glands. It results in a shift of a catabolic state to an anabolic or protein building state.
· It reduces cardiovascular risks by increasing lipolyses (decrease visceral fat).
· It stimulates the immune system, restores sexual vitality, improves moods, decreases cholesterol and body fat.
· It improves memory, increases energy, and has anti-cancer properties by enhancing the immune system.
· It is an endocrine precursor to other hormones, prevents immuno-senescence, loss of sleep, osteoporosis, atherosclerosis.
· DHEA reduces insulin requirement
· Adrenal hormone anabolic vs. catabolic metabolism
· Restores immunity
· Prevents osteoporosis, increases bone density
· Prevents cancer in lab animals
· Prevents diabetes & heart disease
· Decreases visceral fat
· Improves mood & well-being
· Improves energy & memory
· Slows aging process in lab animals
· Prevents lipid peroxidation = antioxidant
· Endocrine precursor to T.P.E.
· 7-keto DHEA is not a precursor to other HRT = avoid
· Neurotransmitter (recently discovered)
· Presently pending FDA approval for Lupus (Prasterone)
Clinically substantiated uses of DHEA include replacement for:
· Low DHEA levels
· Chronic disease
· Adrenal exhaustion or corticosteroid therapy
· SLE
· Improving bone density
· Improving depression & mood disorders
· Enhancing immune response by activating T-cells
· Improving well-being
· Decreasing cardiovascular risk
· Improving erectile dysfunction
· Anyone over 40
· DHEA has never been shown to reverse the aging process
· Nevertheless DHEA is important for preventive medicine
· DHEA inhibits synthesis of thromboxane A2, reduces plasminogen activator inhibitor, and tissue plasminogen activator – all decreasing platelet aggregation and ischemia.
Administration:
Men<200lb: 50mg AM
Men>200lb: 75-100mg AM
Women <50yo: 10-15mg AM
Women >50yo: 25mg AM
IMPORTANT:
DHEA Serum Levels
MEN
· Range 100-600
· Optimal 500-600
WOMEN
· Range 50-300
· Optimal 200-250
Higher levels in women predispose them to side effects – therefore stay low.
· Monitor monthly until optimal
· Assure correct dose and compliance
· Measure DHEA-S and not DHEA
· Side effects: acne, hirsutism
· Tx: Lower dose or take QOD Spironolactone 100 mg/day
· Contraindicated in sex hormone responsive tumors – breast, ovarian, uterine, prostate
· Conversion to T.P.E.?
· DHEA raises testosterone levels in women slightly, yet not in men
· DHEA raises estradiol slightly in men
Indications:
· Over age 40 for health protection
· Preventive medicine and well-being
· Symptoms of aging, mood & depression
· Cause the medical literature suggests it if we want to live longer, happier, healthier
DHEA Dose MEN
Capsule – SR micronized
50 mg Q am
>200 lbs – 75 - 100 mg Q am
WOMEN Capsule – SR micronized
10 mg Q am if over 40
15 mg Q am if over 50
25 mg Q am if over 60
There is a big deal on the type of pill you take. DHEA and Pregnenolone are best taking in a ultra micronized slow release formula. This provides for better uptake and due to short half life insures one is getting what they need through the course of the day.
Here's Dr. Rouizer's presentation, enjoy fellows:
DHEA Supplementation
Dehydroepiandrosterone: DHEA
As presented by Dr. Neal Rouzier, M.D.
Here's a great reason to add DHEA to your protocol.
DHEA is a hormone secreted primarily by the adrenal glands. It results in a shift of a catabolic state to an anabolic or protein building state.
· It reduces cardiovascular risks by increasing lipolyses (decrease visceral fat).
· It stimulates the immune system, restores sexual vitality, improves moods, decreases cholesterol and body fat.
· It improves memory, increases energy, and has anti-cancer properties by enhancing the immune system.
· It is an endocrine precursor to other hormones, prevents immuno-senescence, loss of sleep, osteoporosis, atherosclerosis.
· DHEA reduces insulin requirement
· Adrenal hormone anabolic vs. catabolic metabolism
· Restores immunity
· Prevents osteoporosis, increases bone density
· Prevents cancer in lab animals
· Prevents diabetes & heart disease
· Decreases visceral fat
· Improves mood & well-being
· Improves energy & memory
· Slows aging process in lab animals
· Prevents lipid peroxidation = antioxidant
· Endocrine precursor to T.P.E.
· 7-keto DHEA is not a precursor to other HRT = avoid
· Neurotransmitter (recently discovered)
· Presently pending FDA approval for Lupus (Prasterone)
Clinically substantiated uses of DHEA include replacement for:
· Low DHEA levels
· Chronic disease
· Adrenal exhaustion or corticosteroid therapy
· SLE
· Improving bone density
· Improving depression & mood disorders
· Enhancing immune response by activating T-cells
· Improving well-being
· Decreasing cardiovascular risk
· Improving erectile dysfunction
· Anyone over 40
· DHEA has never been shown to reverse the aging process
· Nevertheless DHEA is important for preventive medicine
· DHEA inhibits synthesis of thromboxane A2, reduces plasminogen activator inhibitor, and tissue plasminogen activator – all decreasing platelet aggregation and ischemia.
Administration:
Men<200lb: 50mg AM
Men>200lb: 75-100mg AM
Women <50yo: 10-15mg AM
Women >50yo: 25mg AM
IMPORTANT:
DHEA Serum Levels
MEN
· Range 100-600
· Optimal 500-600
WOMEN
· Range 50-300
· Optimal 200-250
Higher levels in women predispose them to side effects – therefore stay low.
· Monitor monthly until optimal
· Assure correct dose and compliance
· Measure DHEA-S and not DHEA
· Side effects: acne, hirsutism
· Tx: Lower dose or take QOD Spironolactone 100 mg/day
· Contraindicated in sex hormone responsive tumors – breast, ovarian, uterine, prostate
· Conversion to T.P.E.?
· DHEA raises testosterone levels in women slightly, yet not in men
· DHEA raises estradiol slightly in men
Indications:
· Over age 40 for health protection
· Preventive medicine and well-being
· Symptoms of aging, mood & depression
· Cause the medical literature suggests it if we want to live longer, happier, healthier
DHEA Dose MEN
Capsule – SR micronized
50 mg Q am
>200 lbs – 75 - 100 mg Q am
WOMEN Capsule – SR micronized
10 mg Q am if over 40
15 mg Q am if over 50
25 mg Q am if over 60
Dave Barry
Member
Dhea
I am not an expert on DHEA, but from what I have read, some people seem to believe that European-derived DHEA (99.9% purity) that is micronized, delivers maximum absorption and utilization. Since DHEA is metabolized in the body within 8 hours, it makes sense to take one capsule 3x/day or buy a slower releasing form such as Gene posted so you don't have to worry about taking it multiple x/day. Finally, it is an antagonist to tamoxifen citrate (Nolvadex).
I am not an expert on DHEA, but from what I have read, some people seem to believe that European-derived DHEA (99.9% purity) that is micronized, delivers maximum absorption and utilization. Since DHEA is metabolized in the body within 8 hours, it makes sense to take one capsule 3x/day or buy a slower releasing form such as Gene posted so you don't have to worry about taking it multiple x/day. Finally, it is an antagonist to tamoxifen citrate (Nolvadex).
Last edited:
Gene Devine
Super Moderator
Really nice post Dave!
Keep it up man
Keep it up man
Gene Devine
Super Moderator
A ton!
Go here and do some reading: www.lef.org
Their search function is pretty good but dig around and you will find more than you can read in any one sitting!!!
Also, read Doctor Rouizer's presentation above. He even states in it at one point "Clinically substantiated uses of DHEA include replacement for..." or this "Cause the medical literature suggests it if we want to live longer, happier, healthier".
He didn't make this stuff up and a Physician of his stature presenting this at a major A4M conference would be suicide if he did.
There was a bill in congress here in the states Hugo that wanted to place DHEA as a controlled substance but it didn't get too far.
Taken in the dosages that we want for anti aging effects it's safe and effective.
Go here and do some reading: www.lef.org
Their search function is pretty good but dig around and you will find more than you can read in any one sitting!!!
Also, read Doctor Rouizer's presentation above. He even states in it at one point "Clinically substantiated uses of DHEA include replacement for..." or this "Cause the medical literature suggests it if we want to live longer, happier, healthier".
He didn't make this stuff up and a Physician of his stature presenting this at a major A4M conference would be suicide if he did.
There was a bill in congress here in the states Hugo that wanted to place DHEA as a controlled substance but it didn't get too far.
Taken in the dosages that we want for anti aging effects it's safe and effective.
Gene Devine
Super Moderator
Interesting article here:
http://suppversity.blogspot.com/2013/09/suppversity-science-round-up-seconds.html
http://suppversity.blogspot.com/2013/09/suppversity-science-round-up-seconds.html
Gene Devine
Super Moderator
Gene Devine
Super Moderator
Same with me Kelly.
When I switched to ultra micronized slow release my DHEA-S levels are twice over the reference range and IFG-1 twice as well.
Nelson Vergel
Founder, ExcelMale.com
DHEA is all right but is has marginal benefits and can greatly increase estradiol. Some brands increase liver functions.
Be very careful with DHEA. It is super hyped and has shown good quality of life boost but no boost in erectile function and sex drive in placebo controlled studies. When you are taking 5 things for sex drive and ED, how do you know which one works? Just saying...
https://www.excelmale.com/forum/thr...entation-in-Elderly-Men-A-Meta-Analysis-Study
http://examine.com/supplements/Dehydroepiandrosterone/
Be very careful with DHEA. It is super hyped and has shown good quality of life boost but no boost in erectile function and sex drive in placebo controlled studies. When you are taking 5 things for sex drive and ED, how do you know which one works? Just saying...
https://www.excelmale.com/forum/thr...entation-in-Elderly-Men-A-Meta-Analysis-Study
http://examine.com/supplements/Dehydroepiandrosterone/
Gene Devine
Super Moderator
I don't take it for ED or sex drive as much as I do to make sure that I have the foundational building blocks in place for all hormones.
DHEA and Pregnenelone slow in production with age.
Additionally, I am a believer that the upstream components in our androgen pathway (or all three CHOL pathways) are compromised to some extent with the use of exogenous testosterone...for me, it's insurance.
DHEA and Pregnenelone slow in production with age.
Additionally, I am a believer that the upstream components in our androgen pathway (or all three CHOL pathways) are compromised to some extent with the use of exogenous testosterone...for me, it's insurance.
DR John on Superhuman Radio talking about DHEA
http://www.superhumanradio.com/shr-938-best-of-dhea-for-adrenal-fatigue.html
Guest: Dr. John Crisler
One of the most importsnt hormones for today's high-stress world.
http://www.superhumanradio.com/shr-938-best-of-dhea-for-adrenal-fatigue.html
Guest: Dr. John Crisler
One of the most importsnt hormones for today's high-stress world.
Last edited:
DR John on Superhuman Radio talking about PREGNENOLONE
http://www.superhumanradio.com/460-pregnenolone-the-progenitor-hormone.html
Guest: Dr. John Crisler
Pregnenolone is the parent hormone of every other hormone down stream. Its also available over-the-counter. We discuss benefits of supplementing and potential side effects.
http://www.superhumanradio.com/460-pregnenolone-the-progenitor-hormone.html
Guest: Dr. John Crisler
Pregnenolone is the parent hormone of every other hormone down stream. Its also available over-the-counter. We discuss benefits of supplementing and potential side effects.
SHR # 939 - BEST OF - Pregnenolone The Progenitor Hormone with DR John.
http://www.superhumanradio.com/shr-939-best-of-pregnenolone-the-progenitor-hormone.html
Guest: Dr. John Crisler
Pregnenolone is to the sex hormones what stem cells are to regenerative medicine. Just one click down-stream from cholesterol, its where all other hormones begin.
http://www.superhumanradio.com/shr-939-best-of-pregnenolone-the-progenitor-hormone.html
Guest: Dr. John Crisler
Pregnenolone is to the sex hormones what stem cells are to regenerative medicine. Just one click down-stream from cholesterol, its where all other hormones begin.
SHR # 930 - Benefits Of Supplementing With Pregnenolone And DHEA Combined PLUS ASK THE EXPERT: Brooks Kubik Answers Listener Questions
http://www.superhumanradio.com/shr-...-brooks-kubik-answers-listener-questions.html
http://www.superhumanradio.com/shr-...-brooks-kubik-answers-listener-questions.html
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