Best Test for Insulin Sensitivity/Resistance?

Endlessknight

New Member
Greetings,

I was wondering if anyone new of a single test that measured insulin sensitivity? I get my A1C done once a year in Nov. Last year it was 4.9, but I've read that one can have a healthy A1C and still have significant insulin resistance that can effect T levels. I worry that this case for me. I've always have a problem with sugar. Was labeled pre-diabetic a few years ago. Got my diet under control, but I still binge on high sugar foods and then just work out a lot to burn it off.

Thanks in advance for any input.
 
Taking your fasting glucose every morning for a couple of weeks would be a good start to baseline your levels. There are other tests as well, but I would start there.
 
I did not reach pre diabetes but I felt like I had insulin resistance and was heading towards diabetes from years of low T levels (one of the main reasons I started trt). The a1c is a good test but it does not always tell the full story on insulin resistance because you can get a great score through a low carb diet/exercise even with insulin resistance. The a1c test is better at showing how well you are managing your diabetes.

To really see if you have insulin resistance you can take a test where they will give you a drink with a high amount of sugar and the test your blood sugar 2 hrs after. I took that test but then figured out that by buying a blood sugar monitor I could just perform it myself at home.

In my case, only 10 days on trt and I believe my insulin resistance is quickly improving, I am eating more carbs and my blood sugar is always 80 to 90 2 hrs after a carb heavy meal.
 

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Estradiol (E2)

A form of estrogen produced from testosterone. Important for bone health, mood, and libido. Too high can cause side effects; too low can affect well-being.

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Dihydrotestosterone is a potent androgen derived from testosterone. Affects hair growth, prostate health, and masculinization effects.

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The biologically active form of testosterone not bound to proteins. Directly available for cellular uptake and biological effects.

Scientific Reference

Lakshman KM, Kaplan B, Travison TG, Basaria S, Knapp PE, Singh AB, LaValley MP, Mazer NA, Bhasin S. The effects of injected testosterone dose and age on the conversion of testosterone to estradiol and dihydrotestosterone in young and older men. J Clin Endocrinol Metab. 2010 Aug;95(8):3955-64.

DOI: 10.1210/jc.2010-0102 | PMID: 20534765 | PMCID: PMC2913038

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