Benefit of taking DHEA

Before I started trt, dhea would just convert my testosterone l into estrogen. The more dhea I took the lower of my testosterone went and the higher my estrogen became. Now that I’m on trt, I do supplement with dhea, just to keep it in a good range.
 
I am on TRT also. How much DHEA usually recommended ? I remember one TRT doctor who passed away ( suicidal) used to take DHEA with TRT himself. Some people say DHEA helps with depression, anxtiety.
Pregnenolone 10 mg, 25 mg of DHEA

My levels
DHEA-Sulfate 502.0 H ug/dL
range 30.9-295.6 (age adjusted)
 
Is 100 mg pregnenolone too much? I have it in the SR version. Steady release or slow release. It’s prescription from a compounding pharmacy.
 
I’ve been on and off and definitely feel better on Dhea. My normal level was about 155 which was midpoint for a man my age (early 50s). I take 25 mg nightly and it puts me into the 300s. I feel that this is an important hormone for anti aging and also boosts the immune system.
 
I've been taking DHEA at 50 ang 100mg for a couple months but don't really notice a difference in anything. How long does it take topically?
 
Is 100 mg pregnenolone too much? I have it in the SR version. Steady release or slow release. It’s prescription from a compounding pharmacy.
If you are taking daily then that's likey going to be too high for you. Most start around 5mg and increase from there based in labs and how you feel.
 
not felt anything from DHEA 25mg. but 30-60mg of pregnenolone helps with sleep a lot!
i tried 50+60mg for a while (dhea+P), but i think it is too high. 25+30mg is what I do now. waiting on blood work to see where I'm at
 
not felt anything from DHEA 25mg. but 30-60mg of pregnenolone helps with sleep a lot!
i tried 50+60mg for a while (dhea+P), but i think it is too high. 25+30mg is what I do now. waiting on blood work to see where I'm at
Hello Lukas, when do you take both of these? I take my DHEA at bed but interested in pregnenolone.
 

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TRT Hormone Predictor

Predict estradiol, DHT, and free testosterone levels based on total testosterone

⚠️ Medical Disclaimer

This tool provides predictions based on statistical models and should NOT replace professional medical advice. Always consult with your healthcare provider before making any changes to your TRT protocol.

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Understanding Your Hormones

Estradiol (E2)

A form of estrogen produced from testosterone. Important for bone health, mood, and libido. Too high can cause side effects; too low can affect well-being.

DHT

Dihydrotestosterone is a potent androgen derived from testosterone. Affects hair growth, prostate health, and masculinization effects.

Free Testosterone

The biologically active form of testosterone not bound to proteins. Directly available for cellular uptake and biological effects.

Scientific Reference

Lakshman KM, Kaplan B, Travison TG, Basaria S, Knapp PE, Singh AB, LaValley MP, Mazer NA, Bhasin S. The effects of injected testosterone dose and age on the conversion of testosterone to estradiol and dihydrotestosterone in young and older men. J Clin Endocrinol Metab. 2010 Aug;95(8):3955-64.

DOI: 10.1210/jc.2010-0102 | PMID: 20534765 | PMCID: PMC2913038

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